Search results
Search for "hydrophobic" in Full Text gives 400 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.
Alcohol-perturbed self-assembly of the tobacco mosaic virus coat protein
Beilstein J. Nanotechnol. 2022, 13, 355–362, doi:10.3762/bjnano.13.30
- alcohol having the strongest effect and methanol the weakest. We discuss several effects that may contribute to preventing the protein–protein interactions between disks that are necessary to form helical rods. Keywords: alcohol; hydrophobic effect; protein assembly; self-assembly; tobacco mosaic virus
- effect glycine may have on the disk to rod transition. Lee et al. investigated the coagulation of TMV virions in alcohol–water–LiCl solutions [33]. They concluded that ethanol increases hydrophobic interactions between virions, and LiCl screens electrostatic repulsion, leading to significant aggregation
- . Helical rod assembly was recovered after removal of the ethanol by dialysis in all cases (Figure S3, Supporting Information File 1). These results are consistent with a hydrophobic effect exerted by ethanol. TMV-cp assembly has been shown to be largely driven by hydrophobic effects [40]. It is possible
Coordination-assembled myricetin nanoarchitectonics for sustainably scavenging free radicals
Beilstein J. Nanotechnol. 2022, 13, 284–291, doi:10.3762/bjnano.13.23
- phosphopeptides, exhibited huge therapeutic potential in antioxidant treatments [11][12][13]. Nevertheless, a plenty of disadvantages restrict biomedical applications, namely low biocompatibility of the metal-based nanomaterials, low bioavailability of hydrophobic small-molecule compounds, and easy degradation of
- , and allergens [17]. In spite of the tremendous potential, Myr possesses the same shortcomings as many hydrophobic small molecules, namely low bioavailability, poor water solubility and rapid degradation at pH > 6.8, which limits its clinical therapeutic potential [22]. GSH consists of glycine
Systematic studies into uniform synthetic protein nanoparticles
Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22
- ]. Nanoparticles made of proteins [6] hold significant promise in this respect and different methods have been adopted to fabricate protein-based nanoparticles including nab technology [1], desolvation methods [2], and self-assembly [3]. The protein human albumin is a natural carrier of endogenous hydrophobic
- molecules [7] and has been shown to be an attractive vehicle for hydrophobic drugs in several clinical and preclinical applications [8]. This feature is highlighted in the success of AbraxaneTM, a nanoparticle albumin bound (nab) technology to delivery paclitaxel – a hydrophobic cancer therapeutic
- , particularly as a combination therapy [10]. To leverage the endogenous properties of albumin, nab technology uses a high-pressure manufacturing process to force hydrophobic drugs into the internal hydrophobic pockets of human serum albumin (HSA) [11]. This leads to the formation of albumin-bound, paclitaxel
Effects of drug concentration and PLGA addition on the properties of electrospun ampicillin trihydrate-loaded PLA nanofibers
Beilstein J. Nanotechnol. 2022, 13, 245–254, doi:10.3762/bjnano.13.19
- mechanical properties are examined. The study will also contribute to the production of implantable systems of ampicillin trihydrate, a hydrophobic antibiotic, with a controlled release. Thus, it will allow improvement in treatment efficiency with lower doses of antibiotics, reduce systemic side effects
- the polymers added to PLA. As a result, the hydrophobic antibiotic ampicillin trihydrate had the lowest burst effect and the slowest controlled release with PLA/PLGA nanofibers compared to that of PLA, PCL and PLA/PCL nanofibers. As shown in Figure 5, the absence of the melting endotherm peak at
Engineered titania nanomaterials in advanced clinical applications
Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15
- reported by Rehman [8], who used the photodynamic properties of TiO2 for killing HeLa cancer cells. The hydrophobic nature of photosensitizers commonly used in photodynamic therapy led to selectivity and aggregation issues that jeopardize their effectiveness. Therefore, TiO2 nanoparticles (nps), which
- regarding the hydrophilic or hydrophobic nature of a material as water can percolate more easily inside wider pores than inside smaller pores [22]. Synthesized TiO2 is often covered partially with a layer of hydroxy groups that imparts a negative charge to the surface, making them hydrophilic with a small
- . However, it is hydrophobic and poor cell adhesion has been reported. In a study of Kiran et al., TiO2 nanoparticles (0, 2, 5, and 7 wt %) were suspended in polycaprolactone forming a polymer/ceramic hybrid composite (PCL/TiO2), which was then used as a coating over biomedical grade commercial pure
A comprehensive review on electrospun nanohybrid membranes for wastewater treatment
Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10
- nanofibers were obtained. DMF, the less volatile solvent, promotes the formation of the internal pores. In contrast, the highly volatile THF promotes the surface pore formation in the presence of water vapor, which does not mix with hydrophobic PS [46]. 3.3.2 Temperature. The temperature has two opposing
- hydrophobic PVDF membrane to a hydrophilic membrane with a water contact angle of 22.72°. The nanohybrid membrane showed a dye removal efficiency of 88.9% and an adsorption capacity of 72.6 mg/g for IC [78]. Huong et al. developed a waste protein-immobilized cationic dye removal membrane from PAN. In this
- ENH membranes. The synergistic effect of both the additives and the pristine polymer results in a much better product with enhanced adsorption properties. These additives often provide more functional groups for the adsorption process, simultaneously imparting hydrophilic properties to the hydrophobic
A photonic crystal material for the online detection of nonpolar hydrocarbon vapors
Beilstein J. Nanotechnol. 2022, 13, 127–136, doi:10.3762/bjnano.13.9
- suspension [43]. The formed structure was covered with a hydrophobic polymer material layer, that is, polydimethylsiloxane of a specified thickness, which serves as a sensitive layer and mechanically protects the CCA. Sensors with a glass carrier have better optical characteristics but are inferior to
Sputtering onto liquids: a critical review
Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2
Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles
Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99
- which enables controlled and nontoxic biological interactions [18]. The hydrophilicity of the nanocarriers is important, as native hydrophobic surfaces of NPs are rapidly opsonized by hydrophobic serum proteins [19]. For this, surface functionalization has a major role [18]. It alters the surface
- hydrophobic NPs was achieved by the functionalization with an amphiphilic brush copolymer, poly(isobutylene-alt-maleic anhydride) (PMA) implanted with dodecylamine, which provides biocompatibility, colloidal stability, and hydrophilicity [22]. It is composed of hydrophobic side chains and the backbone of
- hydrophilic groups. The hydrophobic side chains interact with the hydrophobic surfactant (oleic acid) present on the surface of NPs, thereby exposing the hydrophilic end to interact with the aqueous environment and contributing towards a colloidal nanosuspension [23]. The surfaces of the NPs were further
A review on slip boundary conditions at the nanoscale: recent development and applications
Beilstein J. Nanotechnol. 2021, 12, 1237–1251, doi:10.3762/bjnano.12.91
- boundary conditions [10][11][12][13][14][15]. For example, many studies have shown that on hydrophobic surfaces, roughness may lead to a transition to a superhydrophobic state, significantly lowering the ability of liquid drops to stick. In other words, liquids can easily slip along such solid surfaces and
- –liquid interface, and when the thickness of the EDL is much smaller than the characteristic geometrical length, the shape of the velocity profile appears to be plug-like. Nonetheless, many studies have shown that on hydrophobic solid surfaces, the ionized solution driven by an external electric field may
- by many studies that if the amplitude is comparable to or smaller than the local slip length, then an increase in amplitude leads to a reduction of the effective slip length [86][87]. Among those studies, MD simulations conducted by Yang show that compared with the fluid flow at smooth hydrophobic
Self-assembly of amino acids toward functional biomaterials
Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85
- ordered nanostructures through noncovalent interactions, including electrostatic, π–π stacking, van der Waals, and hydrophobic interactions. The self-assembly of single amino acids has the advantages of low synthesis cost, relatively easy modeling [27], and excellent biocompatibility and biodegradability
- and molecular forces play a key role in self-assembly, including hydrogen bonds, hydrophobic bonds, van der Waals force, ionic bonds, π–π stacking, and electrostatic forces [31]. Importantly, amino acids are simple building blocks that provide relevant noncovalent interactions to construct complex
- combinations suggest that all assembled ultrastructures formed from various metabolites exhibit amyloidosis. These metabolites not only self-assemble into supramolecular amyloid fiber structures, but also have significant apoptotic effects on neuron model cells. Singh et al. [36] showed that the hydrophobic
Use of nanosystems to improve the anticancer effects of curcumin
Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78
- . Liposomes are one of the most well-studied nanosystems. They are self-assembled vesicles with at least one phospholipid bilayer with a diameter size in the range of 50–450 nm when used for medical purposes, and are often used to deliver both hydrophilic and hydrophobic molecules [71][72]. Their main
- potential carriers for hydrophobic compounds like CUR, since it can increase its solubility by 1400-fold [90]. When CUR-loaded nanoemulsions were tested, results showed an antiangiogenic effect since there was inhibition of new vessel formation and reduced microvessel density in mice. Moreover, increased
An overview of microneedle applications, materials, and fabrication methods
Beilstein J. Nanotechnol. 2021, 12, 1034–1046, doi:10.3762/bjnano.12.77
- by adsorption [92], with rates of release depending on interaction of the drug with the porous silicon. Oxidation, covalent binding, and electrostatic interactions can all be used to immobilise the drug on the porous silicon [94], while both hydrophilic and hydrophobic molecules can be loaded on
Self-assembly of Eucalyptus gunnii wax tubules and pure ß-diketone on HOPG and glass
Beilstein J. Nanotechnol. 2021, 12, 939–949, doi:10.3762/bjnano.12.70
- interface, covers all aerial non-lignified parts of higher plants [1]. It is an extracellular membrane of epidermal cells, consisting of a matrix of the polymer cutin and a mixture of hydrophobic compounds, the cuticular waxes [2][3]. This interface is a multifunctional surface optimized by evolution to
Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications
Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64
Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material
Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63
- were quantified by means of an antimicrobial surface activity test. First, two 10 g samples of Ag-NPs were prepared according the process described in section “Silver nanoparticle synthesis”. Then, one of the Ag-NP samples was coated with DIO to make its surface hydrophobic and therefore more
- , and the DIO coating was considered successful since qualitative tests showed that Ag/HNT-8/DIO did indeed present hydrophobic behaviour, while Ag/HNT-8 did not. Afterwards, 2 g of Ag/HNT-8 and Ag/HNT-8/DIO were mixed with 650 g of LDPE pellets. Both mixtures were homogenized and moulded into square
- , depending on the type of material. Polyethylene (both low- and high-density) is almost apolar and thus mixes very well with hydrophobic particles and very badly with hydrophilic ones. Qualitative tests have shown that, while Ag/HNT-8 gets wet in water, Ag/HNT-8/DIO is highly hydrophobic. This hydrophobic
Physical constraints lead to parallel evolution of micro- and nanostructures of animal adhesive pads: a review
Beilstein J. Nanotechnol. 2021, 12, 725–743, doi:10.3762/bjnano.12.57
- affinity to substrata with various physicochemical properties (hydrophilic and hydrophobic). In other words, the fluid may be a kind of coupling agent, promoting and strengthening the adhesion between otherwise incompatible materials by providing the proximity of contact for intermolecular forces. At a
Nanogenerator-based self-powered sensors for data collection
Beilstein J. Nanotechnol. 2021, 12, 680–693, doi:10.3762/bjnano.12.54
- intelligence. Wang et al. proposed a hydrophobic polytetrafluoroethylene film and sponge-like graphene/polydimethylsiloxane composite material to prepare a multifunctional self-powered sensor [51]. The sensor can infer the performance of the material through the difference in the output of the electrical
Surface-enhanced Raman scattering of water in aqueous dispersions of silver nanoparticles
Beilstein J. Nanotechnol. 2021, 12, 497–506, doi:10.3762/bjnano.12.40
- by the changes in the Raman spectra of water. Two types of agents can be distinguished: destructive agents (e.g., most ions, temperature, polar molecules) and structure-ordering agents (e.g., apolar molecules, biological macromolecules, or hydrophobic surfaces [19]). The intensity of the OH
The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors
Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31
- ponatinib and SAR302503 are hydrophobic drugs and were co-encapsulated inside the hydrophobic core of PEG–PLA micelles by solvent displacement nanoprecipitation. The results demonstrated that the targeted NDDS enabled a high availability of the drugs inside the BM, which is a prerequisite for overcoming the
A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures
Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9
- fatty acids in a hydrophobic solvent such as alkanes [235]. There is a water phase inside the microemulsions which is also referred to as the water pool where the reactants are present [235]. The water pool is where the silver ions are reduced into silver atoms which then form AgNPs [152]. The reverse
Self-assembly and spectroscopic fingerprints of photoactive pyrenyl tectons on hBN/Cu(111)
Beilstein J. Nanotechnol. 2020, 11, 1470–1483, doi:10.3762/bjnano.11.130
- length 0.29 nm ± 0.05 nm) or was positioned in the hydrophobic pocket between the pyridyl group and the pyrene core of an adjacent molecule (see d2 and d3). trans-like-disubstituted pyrene Figure 3 shows the STM images of the surface after the deposition of the trans-like-disubstituted pyrene derivative
Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action
Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129
- , slightly attract NPs [158]. In addition, the double membrane acts as a selective physical barrier against hydrophobic compounds, such as detergents and antibiotics. On the other hand, Gram-positive bacteria have a higher permeability, even with a thick layer of peptidoglycan, since the single membrane is
- ]. Silver, gold, zinc oxide, and titanium dioxide NPs can be attracted to the cell wall by electrostatic attraction [161], van der Waals forces [162], and hydrophobic interactions [163], inducing changes in the shape, function and permeability of the cells. Proteins and DNA Proteins play a fundamental role
Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms
Beilstein J. Nanotechnol. 2020, 11, 1134–1146, doi:10.3762/bjnano.11.98
- biofilm viable count was ≈2.5–6.0 log cycle upon laser excitation with different gold nanoparticle concentrations. Previously, the same research group studied the photothermal bactericidal activity of hydrophilic and hydrophobic functionalized gold nanorods against S. aureus and Propionibacterium acnes by
Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements
Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94
- hydrophobic surfaces that induce aggregation and/or the formation of large clusters. When in contact with biological structures, this mechanism provokes capillary clotting and reduces tissue and cellular absorption. To prevent this, nanoparticles are coated with stabilizers, which are added during preparation
- commonly used for SPION coating, yielding good nanoparticle stability and no cytotoxicity. It is currently the preferred coating for MRI nanoparticles [54][76][84]. Depending on the type of emulsifier used, the coating can be hydrophilic or hydrophobic, but it is common to use hydrophilic polymers, such as
- PVA or PEG, for drug release studies [33][76] because the hydrophobic polymers are rapidly uptaken by macrophages [85]. SPIONs coated with a mixture of PVA and polyvinyl amine were shown to induce very active mitochondrial and endocytic processes in cells and to be highly toxic to cells due to the
Other Beilstein-Institut Open Science Activities
