Extracellular biosynthesis of gadolinium oxide (Gd₂O₃) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol

• Shadab Ali Khan,
• Sanjay Gambhir and
• Absar Ahmad

Beilstein J. Nanotechnol. 2014, 5, 249–257, doi:10.3762/bjnano.5.27

• absorption edge at ca. 270 nm arises due to electronic transitions in the delocalized π-electrons present in the indole ring of aromatic amino acids such as tryptophan, tyrosine and to some extent phenylalanine residues, which are present in the proteins moiety [24]. These residues of proteins may be

Nanoscopic surfactant behavior of the porin MspA in aqueous media

• Ayomi S. Perera,
• Hongwang Wang,
• Tej B. Shrestha,
• Deryl L. Troyer and
• Stefan H. Bossmann

Beilstein J. Nanotechnol. 2013, 4, 278–284, doi:10.3762/bjnano.4.30

• . Results and Discussion MspA (porin A from M. smegmatis), an octameric channel protein (184 amino acids, Mw = 155,248 Da [20]) is isolated from the outer cell wall of M. smegmatis, a species of nonpathogenic mycobacteria commonly found in soil [21]. The structure of MspA has been studied extensively and

• without denaturation. The MspA-octamer is formed by 160 negatively charged and 64 positively charged amino acids [2]. R165 and E63/E127, as well as R161 and E39, form salt bridges, which greatly stabilize its tertiary structure (R: arginine, E: glutamic acid) [2]. As a result, 136 negatively charged and

• 48 positively charged amino acids are accessible at the surface. Whereas the negative charges are predominantly found within the interior of the “goblet”, positive charges are concentrated in the stem and the periplasmatic loop region of MspA (Figure 1B and Figure 1C). We have investigated the

Distinction of nucleobases – a tip-enhanced Raman approach

• Regina Treffer,
• Xiumei Lin,
• Elena Bailo,
• Tanja Deckert-Gaudig and
• Volker Deckert

Beilstein J. Nanotechnol. 2011, 2, 628–637, doi:10.3762/bjnano.2.66

• orientation of the ring on the gold surface. Similar effects were found to influence the ring breathing mode of aromatic amino acids [31]. Apart from this difference the spectral features can be attributed solely to uracil and no signals of the sugar and phosphate backbone were found. This suggests a strong

Self-organizing bioinspired oligothiophene–oligopeptide hybrids

• Alexey K. Shaytan,
• Eva-Kathrin Schillinger,
• Elena Mena-Osteritz,
• Sylvia Schmid,
• Pavel G. Khalatur,
• Peter Bäuerle and
• Alexei R. Khokhlov

Beilstein J. Nanotechnol. 2011, 2, 525–544, doi:10.3762/bjnano.2.57

• (SPPS) by sequential coupling of standard fluorenylmethoxycarbonyl (Fmoc)-protected amino acids and the pseudoproline unit onto a preloaded TentaGel resin [27]. Incorporation of the Fmoc-protected azido-phenylalanine (aPhe) and the addition of the switch ester segment between valine (Val) and threonine

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes

• Haitao Zheng,
• Leyi Lin,
• Yosuke Okezaki,
• Ryushi Kawakami,
• Haruhiko Sakuraba,
• Toshihisa Ohshima,
• Keiichi Takagi and
• Shin-ichiro Suye

Beilstein J. Nanotechnol. 2010, 1, 135–141, doi:10.3762/bjnano.1.16

• require considerable time for analysis. In recent years, researchers have paid much more attention to the construction of electrochemical enzyme biosensors for the analysis of amino acids [5][6][7], and several electrochemical biosensing systems for L-proline and D-proline determination have been reported

Review and outlook: from single nanoparticles to self-assembled monolayers and granular GMR sensors

• Alexander Weddemann,
• Inga Ennen,
• Anna Regtmeier,
• Camelia Albon,
• Annalena Wolff,
• Katrin Eckstädt,
• Nadine Mill,
• Michael K.-H. Peter,
• Jochen Mattay,
• Carolin Plattner,
• Norbert Sewald and
• Andreas Hütten

Beilstein J. Nanotechnol. 2010, 1, 75–93, doi:10.3762/bjnano.1.10

• hydrophilic. The hydrophilic C-terminal of Mms6 is believed to be the iron binding site [26]. Recent studies within our group showed that nanoparticles can be synthesized in vitro by the use of a shorter synthetic version of the protein Mms6 called c25-mms6. This polypeptide consists of 25 amino acids from