Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• affects the targeting ability of the nanoformulation. In this review, we provide recent findings to highlight several antibody conjugation methods such as adsorption, covalent conjugation, and biotin–avidin interaction. This review also provides an overview of the many effects of the protein corona and

• antigen binding ability. Improper antibody conjugation influences antigen binding affinity and specificity. Once injected into the body, the ACNPs face both physical and biological barriers (such as diffusion, flow and shear forces, aggregation, protein adsorption, phagocytic sequestration, and clearance

• surface charge [36][37]. Surface modification strategies include, for example, adsorption, covalent conjugation, and biotin–avidin interaction, which will be discussed below in detail with examples. Adsorption Adsorption of antibodies on the surface of NPs is a non-covalent reversible binding method

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• ) indicated superior catalytic activity compared to MIL-125(Ti). Notably, MOF-210 has established a remarkable record in CO2 adsorption among all porous materials, boasting an adsorption capacity of 2870 mg·g−1 [34]. Such properties facilitate favorable interactions between CO2 molecules and catalytic sites

• exhibited the highest activity for CO2RR to carbon monoxide (FE = 81% at −1.1 V vs RHE). This can be explained by the fact that ZIF-8 has the smallest adsorption energy of hydrogen, facilitating the desired CO2RR process. The outcomes of this study serve as a foundation for the exploration of transition

• −1.0 V (RHE), whereas the values were 48.8% and 34.7% for Fe-doped ZIF-8 and Ni-doped ZIF-8 at −1.2 V (RHE), respectively (Figure 4b). These results were confirmed by theoretical calculations, which indicated the lowest COOH adsorption energy of Cu-doped ZIF-8 (Figure 4c). Cu-based MOF nanomaterials Cu

Two-dimensional molecular networks at the solid/liquid interface and the role of alkyl chains in their building blocks

• Suyi Liu,
• Yasuo Norikane and
• Yoshihiro Kikkawa

Beilstein J. Nanotechnol. 2023, 14, 872–892, doi:10.3762/bjnano.14.72

• the molecular arrangement and orientation. Among the non-covalent interactions, dispersion interactions that derive from alkyl chain units are believed to be weak. However, alkyl chains play an important role in the adsorption onto substrates, as well as in the in-plane intermolecular interactions. In

• , halogen bonding, and metal coordination, are often exploited for the formation of 2D structures. However, dispersion forces originating from the alkyl chains also play an important role in the adsorption onto the substrate, as well as in the in-plane intermolecular interactions at the solid/liquid

• alkyl chains in 2D nanoarchitectures at the solid/liquid interface. Review 1 Adsorption of alkyl chains The first step in the formation of self-assembled structures at the HOPG/solvent interface is the adsorption of molecules via dispersion forces deriving from alkyl chains and other moieties such as

A wearable nanoscale heart sound sensor based on P(VDF-TrFE)/ZnO/GR and its application in cardiac disease detection

• Yi Luo,
• Jian Liu,
• Jiachang Zhang,
• Yu Xiao,
• Ying Wu and
• Zhidong Zhao

Beilstein J. Nanotechnol. 2023, 14, 819–833, doi:10.3762/bjnano.14.67

• -TrFE). Graphene (GR) exhibits outstanding electrical conductivity and strong adsorption capabilities. When combined with ZnO, it forms a more homogeneous and compact structure, thereby enhancing the alignment and arrangement of ZnO crystals. Furthermore, the layered structure of GR enables it to enwrap

Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity

• Nguyen Thi Thanh Tu,
• T. Lan-Anh Vo,
• T. Thu-Trang Ho,
• Kim-Phuong T. Dang,
• Van-Dung Le,
• Phan Nhat Minh,
• Chi-Hien Dang,
• Vinh-Thien Tran,
• Van-Su Dang,
• Tran Thi Kim Chi,
• Hieu Vu-Quang,
• Radek Fajgar,
• Thi-Lan-Huong Nguyen,
• Van-Dat Doan and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64

• surface characteristics and concentration of nanocatalyst, which directly impact the binding/adsorption capability of the reactant and the release/desorption of the reaction products [49]. This study aims to investigate the catalytic activity of the nanocomposite AgNPs@Lac/Alg for the degradation of two

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• , distribution, and toxicity of nanoceria within biological systems. Cellular uptake studies of nanoceria in lung adenocarcinoma (A549) cells favored particles with a negative zeta potential. However, positively charged particles resulted in greater bovine serum albumin adsorption. This suggests that surface

Control of morphology and crystallinity of CNTs in flame synthesis with one-dimensional reaction zone

• Muhammad Hilmi Ibrahim,
• Norikhwan Hamzah,
• Mohd Zamri Mohd Yusop,
• Ni Luh Wulan Septiani and
• Mohd Fairus Mohd Yasin

Beilstein J. Nanotechnol. 2023, 14, 741–750, doi:10.3762/bjnano.14.61

• widely accepted vapor–liquid–solid mechanism, the growth of CNTs occurs in three steps, namely, melting of nickel particles, adsorption of carbon atoms onto the surface of the metallic nickel, and finally, diffusion and deposition of the precipitated carbon, which forms tubular materials by curling of

Cross-sectional Kelvin probe force microscopy on III–V epitaxial multilayer stacks: challenges and perspectives

• Mattia da Lisca,
• José Alvarez,
• James P. Connolly,
• Nicolas Vaissiere,
• Karim Mekhazni,
• Jean Decobert and
• Jean-Paul Kleider

Beilstein J. Nanotechnol. 2023, 14, 725–737, doi:10.3762/bjnano.14.59

• and, thus, on the measured VCPD. All these aspects can lead to surface inhomogeneities, which result in VCPD variations compared to an otherwise constant measurement on bulk material. KPFM analysis was carried out under ambient conditions, which result in surface oxidation and in the adsorption of

Humidity-dependent electrical performance of CuO nanowire networks studied by electrochemical impedance spectroscopy

• Jelena Kosmaca,
• Juris Katkevics,
• Jana Andzane,
• Raitis Sondors,
• Liga Jasulaneca,
• Raimonds Meija,
• Kiryl Niherysh,
• Yelyzaveta Rublova and
• Donats Erts

Beilstein J. Nanotechnol. 2023, 14, 683–691, doi:10.3762/bjnano.14.54

• adsorption sites (S), for example, in a reaction: [30], may contribute to accumulation of holes near the surface (Figure 3c) [12][14][31]. Then, upon exposure to humidity, the conductivity reduces; impedances measured at RH 5–20% (ca. 0.5 GΩ) are lower than impedances of 2–8 GΩ measured in the RH region of

• 20–50% (Figure 3a). Possibly, at these RH levels, the concentration of free charge carriers in the CuO nanowires reduces, as hole trapping [32] occurs due to adsorption of gaseous H2O molecules on the CuO surface, dissociation in H+ and OH−, and formation of surface dipoles (Cu+–OH−). Water reactions

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• developing luminescent sensors include their toxicity, ease of aggregation, photobleachability, and low capacity for adsorption of the target analyte. Numerous luminescent materials, including semiconductors, metal complexes, metal-based fluorescent nanoparticles, MOFs, and inorganic phosphors doped with

• luminescence, and a desirable adsorption capacity that can enhance MOF–target analyte interactions and transduce these interactions into measurable optical responses. A nanoscale MOF (In-sbdc) with a significant quantum yield of 13% and stable emission in water, for instance, was synthesised by Liu et al. [42

• in MOFs can either be quenched or enhanced. Due to their exceptional characteristics, MOFs have found usage in a variety of fields, including sensors, gas adsorption, energy storage, drug delivery, catalysis, water treatment, and bio-medical imaging [89][90][91][92][93][94][95][96][97][98][99][100

Titania nanoparticles for photocatalytic degradation of ethanol under simulated solar light

• Evghenii Goncearenco,
• Iuliana P. Morjan,
• Claudiu Teodor Fleaca,
• Florian Dumitrache,
• Elena Dutu,
• Monica Scarisoreanu,
• Valentin Serban Teodorescu,
• Alexandra Sandulescu,
• Crina Anastasescu and
• Ioan Balint

Beilstein J. Nanotechnol. 2023, 14, 616–630, doi:10.3762/bjnano.14.51

• are shown in Figure 4d and were fitted with two peaks. The peaks at binding energies of 529.9 and 530.5 eV are attributed, respectively, to oxygen bound to Ti4+ and the adsorption of –OH on the surface [50][51]. The XPS results do not show differences between the two series of samples and do not

ZnO-decorated SiC@C hybrids with strong electromagnetic absorption

• Liqun Duan,
• Zhiqian Yang,
• Yilu Xia,
• Xiaoqing Dai,
• Jian’an Wu and
• Minqian Sun

Beilstein J. Nanotechnol. 2023, 14, 565–573, doi:10.3762/bjnano.14.47

• photocatalysis, adsorption, and EM absorption [25]. Researchers have developed ZnO-based absorbing materials with different microstructures, such as core–shell structures [26], flower-like structures [27], rod-like structures [28], cage-like structures, and nanoparticles [29][30]. Wu et al. demonstrated that it

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35

• were successfully synthesized by sequential coupling of CF3-substituted copper, cobalt, and palladium porphyrins on the surface. The assembly of different porphyrin oligomers combines multiple functional properties such as gas adsorption and magnetism in a one-dimensional structure. This approach could

The steep road to nonviral nanomedicines: Frequent challenges and culprits in designing nanoparticles for gene therapy

• Yao Yao,
• Yeongun Ko,
• Grant Grasman,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2023, 14, 351–361, doi:10.3762/bjnano.14.30

• mid-size molecular probes that bind and associate nonspecifically (structural adsorption, intercalation, or backbone interactions) or through explicit interactions with specific NAT residues [56]. Ultimately, the particulate structure of these systems can result in transport constraints into and

Polymer nanoparticles from low-energy nanoemulsions for biomedical applications

• Santiago Grijalvo and
• Carlos Rodriguez-Abreu

Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29

• (non-adsorbed) surfactant can be in the form of micelles that coexist with the nanoemulsion droplets. The kinetics of surfactant adsorption during droplet formation, droplet coarsening, as well as uncertainties in the estimation of as could also explain the divergences between calculated and

Bismuth-based nanostructured photocatalysts for the remediation of antibiotics and organic dyes

• Akeem Adeyemi Oladipo and
• Faisal Suleiman Mustafa

Beilstein J. Nanotechnol. 2023, 14, 291–321, doi:10.3762/bjnano.14.26

• treat contaminated water and wastewater, including adsorption, bioremediation, precipitation, electrocoagulation, filtration, membrane separation, flocculation, centrifugation, advanced oxidation processes based on photocatalysis, and chemical coagulation [4][5][6][7][8][9][10][11]. Each of these

• precipitation, in particular, are believed to be ineffective [4][11]. As a result of the non-biodegradable and persistent nature of the majority of organic contaminants, some physicochemical treatment techniques, such as adsorption, are ineffective in removing them from water resources [11]. Because of their

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• with hyaluronic acid–doxorubicin NPs layered by electrostatic adsorption upon the micelle surface. Hyaluronic acid was used for CD44 targeting (a receptor that is often overexpressed on the surface of lung tumor cells), as well as for the optimization of biodistribution, improved tumor homing potential

A novel approach to pulsed laser deposition of platinum catalyst on carbon particles for use in polymer electrolyte membrane fuel cells

• Bogusław Budner,
• Wojciech Tokarz,
• Sławomir Dyjak,
• Andrzej Czerwiński,
• Bartosz Bartosewicz and
• Bartłomiej Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 190–204, doi:10.3762/bjnano.14.19

• characterized in terms of their specific surface area (SBET) and pore volume. The N2 measured adsorption–desorption curves are shown in Figure 2. The SBET, calculated on their basis, is 204 m2/g for C-11 and 244 m2/g for Vulcan XC-72R. The calculated volume of micropores is 0.07 cm3/g for C-11 and 0.10 cm3/g

• mesoporosity, i.e., a wider hysteresis loop and a higher isotherm with p/p0 values approaching 1. Both isotherms (i.e., of XC-72R and C-11) can be classified as type II (according to IUPAC classification [39]) but with H3-type hysteresis loops. A sharp increase of N2 adsorption capacity at p/p0 values

• based on N2 adsorption–desorption measurements performed at liquid nitrogen temperature using an Autosorb IQ analyzer (Quantachrome Instruments – Anton Paar, United States). The samples were outgassed at 250 °C for 10 h prior to analysis. The Brunauer–Emmett–Teller specific surface area (SBET) was

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• adsorption isotherm curve of RhB [49][50]. The plateau in the SERS response observed between 10−8 and 10−10 mol·L−1 can be assigned to either the saturation of the chemical sites (i.e., no supplementary absorption is made) or to the fact that RhB continued to be absorbed outside of the hot spot [6][51

Atmospheric water harvesting using functionalized carbon nanocones

• Fernanda R. Leivas and
• Marcia C. Barbosa

Beilstein J. Nanotechnol. 2023, 14, 1–10, doi:10.3762/bjnano.14.1

• different processes to develop AWH such as condensing and collecting moisture, cooling ambient air below its dew point [10][11], and using chemical and physical processes involving absorption and adsorption [9][12][13]. Many of these mechanisms are inspired by structures found in nature (biomimetic designs

Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin

• Polina M. Kalachikova,
• Anastasia E. Goldt,
• Eldar M. Khabushev,
• Timofei V. Eremin,
• Timofei S. Zatsepin,
• Elena D. Obraztsova,
• Konstantin V. Larionov,
• Liubov Yu. Antipina,
• Pavel B. Sorokin and
• Albert G. Nasibulin

Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130

• SWCNTs occurs due to the adsorption of π-conjugated isoalloxazine moieties on the surface of small-diameter nanotubes and interactions between hydroxy groups of ribityl chains with water. During the SWCNT extraction, specific adsorption of riboflavin to SWCNTs leads to the minimization of interactions

• electronic structure of nanotubes. To gain insights into the correlation between SWCNT diameter and the adsorption of riboflavin, we performed single-step chirality enrichment of SWCNT dispersions with various diameter distributions: CoMoCat SWCNTs with a mean diameter 0.81 nm [24] and Tuball nanotubes with

• Sephacryl gel is an allyl dextran copolymer, and its dextran links act as adsorption sites for SWCNTs in gel chromatography separation [25]. As SWCNTs are wrapped by riboflavin, there are two possible sites of SWCNT–dextran interaction, namely over two ribityl side chains (Figure 5a) and on the edge of

Induced electric conductivity in organic polymers

• Konstantin Y. Arutyunov,
• Anatoli S. Gurski,
• Vladimir V. Artemov,
• Alexander L. Vasiliev,
• Azat R. Yusupov,
• Danfis D. Karamov and
• Alexei N. Lachinov

Beilstein J. Nanotechnol. 2022, 13, 1551–1557, doi:10.3762/bjnano.13.128

• temperature of 150–200 °C for 45 min. Depending on the concentration of the solutions, it was possible to obtain films of various thicknesses from several nm to several μm. The formation of films from dilute solutions occurs according to the mechanism of linear or loop adsorption, when macromolecules at the

Non-stoichiometric magnetite as catalyst for the photocatalytic degradation of phenol and 2,6-dibromo-4-methylphenol – a new approach in water treatment

• Joanna Kisała,
• Anna Tomaszewska and
• Przemysław Kolek

Beilstein J. Nanotechnol. 2022, 13, 1531–1540, doi:10.3762/bjnano.13.126

• the adsorption of organic compounds onto the surface of the catalyst. The sorption power depends largely on the properties of the organic molecule in question, as well as on the properties of the catalyst’s surface. The test reactions were carried out in aqueous solution at pH 8 (due to the hydrolytic

• CurTiPot [28] based on the published pKa values for solutes (Figure 3). The resulting values were as follows: DBMP (0.112); DBMP− (0.888); PhOH (0.987); and PhO− (0.013). The properties of the catalyst’s surface are essential in photocatalysis. Adsorption of organic compounds on the surface of the catalyst

• transfer can occur during the adsorption of organic compounds on magnetite. In the presence of adsorbed aryl halogenated compounds on the catalyst surface, the accumulated electrons are available to activate carbon–halogen bonds via dissociative electron transfer [38][39]. The electron from the catalyst

Structural studies and selected physical investigations of LiCoO₂ obtained by combustion synthesis

• Monika Michalska,
• Paweł Ławniczak,
• Tomasz Strachowski,
• Adam Ostrowski and
• Waldemar Bednarski

Beilstein J. Nanotechnol. 2022, 13, 1473–1482, doi:10.3762/bjnano.13.121

• determined using the BET nitrogen adsorption isotherm method. The measurements were carried out with a QUADRASORB evo instrument (QUANTACHROME Instruments, USA). Before measurements, the samples were degassed for 5 h under vacuum. LiCoO2 was degassed at 200 °C. The purpose of degassing is to remove

• impurities from the surface of the tested material. Adsorption measurements were performed with nitrogen at 77 K. For each sample, an analysis was performed at 15 measurement points in the range of 0.05–0.3 P/P0 (relative pressure). This is the range of the SSA study. Above this range, the trend line bends

• measurements Table 1 shows the results of the SSA measurements determined by the BET adsorption isotherm method. The SSA value decreased with increasing temperature, and, thus, the size of the crystallites increased, as expected. The highest value was obtained for the sample heated at 450 °C, while the lowest

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

• Sedat Ünal,
• Osman Doğan and
• Yeşim Aktaş

Beilstein J. Nanotechnol. 2022, 13, 1393–1407, doi:10.3762/bjnano.13.115

• adsorption of CS macromolecules on the surface of the NPs [42]. Besides coating, drug loading to NPs also led to remarkable changes in particle size. Moreover, after CS coating, the zeta potential of PLGA NPs changed from negative to positive. The negative zeta potential is attributed to the presence of

• the NPs. In the literature, there are several studies claiming that CS enhances the entrapment efficiency of NP systems [46][47][48]. While CS coats the surface of the NP, it also allows for the adsorption of the drug molecules on the NP surface [49]. Thus, NPs can entrap more drug molecules. Our