Microfluidic setup for on-line SERS monitoring using laser induced nanoparticle spots as SERS active substrate

• Oana-M. Buja,
• Ovidiu D. Gordan,
• Nicolae Leopold,
• Andreas Morschhauser,
• Jörg Nestler and
• Dietrich R. T. Zahn

Beilstein J. Nanotechnol. 2017, 8, 237–243, doi:10.3762/bjnano.8.26

• (SERS) has been proven to be a suitable tool for rapid detection of pollutants [3][5][6][7][8], based on their specific molecular fingerprint spectra [9]. The high sensitivity of this spectroscopic technique originates from the pronounced enhancement of the inelastic scattering when the molecule is

Graphene–polymer coating for the realization of strain sensors

• Carmela Bonavolontà,
• Carla Aramo,
• Massimo Valentino,
• Giampiero Pepe,
• Sergio De Nicola,
• Gianfranco Carotenuto,
• Angela Longo,
• Mariano Palomba,
• Simone Boccardi and
• Carosena Meola

Beilstein J. Nanotechnol. 2017, 8, 21–27, doi:10.3762/bjnano.8.3

• . The high sensitivity in addition to high stability of the graphene/PMMA structure and the high thermal sensitivity in the infrared wavelength region are interesting aspects that enable us to propose this polymer/graphene supported coating as a new kind of stress sensor useful for applications in

Nanostructured SnO₂–ZnO composite gas sensors for selective detection of carbon monoxide

• Paul Chesler,
• Cristian Hornoiu,
• Susana Mihaiu,
• Cristina Vladut,
• Jose Maria Calderon Moreno,
• Mihai Anastasescu,
• Carmen Moldovan,
• Bogdan Firtat,
• Costin Brasoveanu,
• George Muscalu,
• Ion Stan and
• Mariuca Gartner

Beilstein J. Nanotechnol. 2016, 7, 2045–2056, doi:10.3762/bjnano.7.195

• , cross-response and recovery characteristics of the analyzed materials are reported. The high sensitivity (RS = 1.21) to low amounts of CO (5 ppm) was reported for the sensor containing a composite sensitive film with ZnO (98 wt %)–SnO2 (2 wt %). This sensor response to CO was five times higher as

• technologies, low power requirements, quick response times (seconds), high sensitivity to small concentrations of a specific gas, complete sensor recovery, lightweight, and long term stability. More recently, sensors were fabricated with reduced dimensions (miniaturization or microelectronic processing) [2][3

Layered composites of PEDOT/PSS/nanoparticles and PEDOT/PSS/phthalocyanines as electron mediators for sensors and biosensors

• Celia García-Hernández,
• Cristina García-Cabezón,
• Fernando Martín-Pedrosa,
• José Antonio De Saja and
• María Luz Rodríguez-Méndez

Beilstein J. Nanotechnol. 2016, 7, 1948–1959, doi:10.3762/bjnano.7.186

• character which is an intrinsic semiconductor) [9][16][17][18]. On the other hand, enzymatic electrochemical biosensors based on phenol oxidases are a good alternative to analyze phenols due to their high sensitivity and selectivity. Tyrosinase oxidizes monophenols and o-diphenols to the corresponding

• of 10−6 mol·L−1. Conclusion Owing to their unique electrochemical properties, layered composite PEDOT/PSS/EM and PEDOT/PSS/EM-Enz electrodes offer efficient electron transfer, low detection limit, high sensitivity and good reproducibility toward the oxidation of catechol and hydroquinone. Furthermore

Monolayer graphene/SiC Schottky barrier diodes with improved barrier height uniformity as a sensing platform for the detection of heavy metals

• Ivan Shtepliuk,
• Jens Eriksson,
• Volodymyr Khranovskyy,
• Tihomir Iakimov,
• Anita Lloyd Spetz and
• Rositsa Yakimova

Beilstein J. Nanotechnol. 2016, 7, 1800–1814, doi:10.3762/bjnano.7.173

• characteristics of the devices and their sensitivity. A simpler solution is to use Schottky diode sensors, which can be grown more easily, have no gate insulator and a high sensitivity in the reverse and forward diode regimes. During the last decade the thermal decomposition of silicon carbide (SiC) in argon

• the selectivity toward cadmium and mercury (Figure 10). It can be explained by the fact that the graphene has a greater binding affinity for lead atoms than for other heavy metal atoms. Because of the high sensitivity of the work function of graphene to adsorbates (in our case, heavy metal atoms), as

• selectively detect Pb atoms in the concentration range up to 67.2 wt % (2 Pb atoms per 16 carbon atoms) with a high sensitivity. Our findings expectedly offer a new reliable strategy to develop portable and real-time environmental sensors based on uniform self-organized graphene/SiC Schottky diodes. Sketch of

Nanostructured TiO₂-based gas sensors with enhanced sensitivity to reducing gases

• Wojciech Maziarz,
• Anna Kusior and
• Anita Trenczek-Zajac

Beilstein J. Nanotechnol. 2016, 7, 1718–1726, doi:10.3762/bjnano.7.164

• selectivity to CO(CH3)2 after sensitization by SnO2 nanoparticles. The sensor response time was of the order of several seconds. Their fast response, high sensitivity to selected gas species, improved selectivity and stability suggest that the SnO2-decorated flower-like 3D nanostructures are a promising

Nanoanalytics for materials science

• Thilo Glatzel and
• Tom Wirtz

Beilstein J. Nanotechnol. 2016, 7, 1674–1675, doi:10.3762/bjnano.7.159

• high-sensitivity chemical information at the nanoscale are of utmost importance for future developments [1]. One of the possible approaches is based on bimodal or even multimodal nanoanalysis, which was increasingly developed during the last decade. Other important aspects that have to be considered

Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

• Christa Genslein,
• Peter Hausler,
• Eva-Maria Kirchner,
• Rudolf Bierl,
• Antje J. Baeumner and
• Thomas Hirsch

Beilstein J. Nanotechnol. 2016, 7, 1564–1573, doi:10.3762/bjnano.7.150

• environmental monitoring providing important features such as real time measurements, high sensitivity and label-free assay [8]. The detection of highly diluted concentrations and small molecules (<200 Da) remains challenging within SPR sensing [9]. For (bio)analytical applications the sensitivity needs to be

• of 5–60 nm [14][15]. An enhancement of local electromagnetic fields and intense absorption bands due to excitations of electrons at the nano-structures, results in a high sensitivity towards local changes of the refractive index [16]. A variety of nanostructured substrates, such as nanostructured

Dynamic of cold-atom tips in anharmonic potentials

• Tobias Menold,
• Peter Federsel,
• Carola Rogulj,
• Hendrik Hölscher,
• József Fortágh and
• Andreas Günther

Beilstein J. Nanotechnol. 2016, 7, 1543–1555, doi:10.3762/bjnano.7.148

• particle interactions and anharmonic motion have a significant impact on the tip dynamics. Conclusion: Our findings will be crucial for the realization of high-sensitivity force spectroscopy with cold-atom tips and could possibly allow for the development of advanced spectroscopic techniques such as Q

A composite structure based on reduced graphene oxide and metal oxide nanomaterials for chemical sensors

• Vardan Galstyan,
• Elisabetta Comini,
• Iskandar Kholmanov,
• Andrea Ponzoni,
• Veronica Sberveglieri,
• Nicola Poli,
• Guido Faglia and
• Giorgio Sberveglieri

Beilstein J. Nanotechnol. 2016, 7, 1421–1427, doi:10.3762/bjnano.7.133

• ][6]. During the last decades, different types of sensors were fabricated for environmental and health monitoring. Among the different detection systems, chemical sensors based on metal oxide nanomaterials are highly demanded because of their high sensitivity, small size, low cost and low power

Ammonia gas sensors based on In₂O₃/PANI hetero-nanofibers operating at room temperature

• Qingxin Nie,
• Zengyuan Pang,
• Hangyi Lu,
• Yibing Cai and
• Qufu Wei

Beilstein J. Nanotechnol. 2016, 7, 1312–1321, doi:10.3762/bjnano.7.122

• even death [5][6][7]. So, there is an urgent need to develop a kind of gas sensor with high sensitivity and selectivity to detect NH3 at room temperature. Metal oxide semiconductors can be applied as sensing materials for monitoring NH3. Ammonia sensors based on In2O3 [8], TiO2 [9], SnO2 [10], ZnO [11

An ellipsometric approach towards the description of inhomogeneous polymer-based Langmuir layers

• Falko O. Rottke,
• Burkhard Schulz,
• Klaus Richau,
• Karl Kratz and
• Andreas Lendlein

Beilstein J. Nanotechnol. 2016, 7, 1156–1165, doi:10.3762/bjnano.7.107

• , e.g., thickness at the nm scale. In the present work only Δ-maps were recorded because of their high sensitivity towards thickness variations, even at ultrathin film conditions [6]. The complications and theoretical problems of estimating extremely small dispersions of Ψ for ultrathin films is known

Experimental and simulation-based investigation of He, Ne and Ar irradiation of polymers for ion microscopy

• Lukasz Rzeznik,
• Yves Fleming,
• Tom Wirtz and
• Patrick Philipp

Beilstein J. Nanotechnol. 2016, 7, 1113–1128, doi:10.3762/bjnano.7.104

• . Keywords: Helium ion microscopy; irradiation; polymers; preferential sputtering; secondary ion mass spectrometry; simulations; Introduction Progress in materials and life sciences requires sample characterisation with high lateral resolution and high sensitivity. A technique which allows for both is

Voltammetric determination of polyphenolic content in pomegranate juice using a poly(gallic acid)/multiwalled carbon nanotube modified electrode

• Refat Abdel-Hamid and
• Emad F. Newair

Beilstein J. Nanotechnol. 2016, 7, 1104–1112, doi:10.3762/bjnano.7.103

• transfer on bare GCE or MWCNT/GCE. Thus the modification enhances the redox peak current and could be used with high sensitivity. Recently, the use of nanomaterials for electrode modification has grown exponentially, owing to their advantageous electrochemical properties. Carbon nanotubes are the main

NO gas sensing at room temperature using single titanium oxide nanodot sensors created by atomic force microscopy nanolithography

• Li-Yang Hong and
• Heh-Nan Lin

Beilstein J. Nanotechnol. 2016, 7, 1044–1051, doi:10.3762/bjnano.7.97

• attractive than conventional devices [9]. The advantages include high sensitivity, high stability, fast detection and recovery, low power consumption, relatively low cost, and small size [9][10]. These advantages enable semiconducting metal oxide sensors to be implemented on integrated circuits for portable

Signal enhancement in cantilever magnetometry based on a co-resonantly coupled sensor

• Julia Körner,
• Christopher F. Reiche,
• Thomas Gemming,
• Bernd Büchner,
• Gerald Gerlach and
• Thomas Mühl

Beilstein J. Nanotechnol. 2016, 7, 1033–1043, doi:10.3762/bjnano.7.96

• where the latter allows for very high sensitivity and the micrometer size part for an easy detection [9]. We will only briefly review the theoretical considerations regarding the sensor concept since it is discussed in depth elsewhere [9]. The main focus of this publication is to demonstrate the

• the co-resonant coupling this changes the resonance frequencies of the coupled system and can be detected at the cantilever. Small interactions result in rather large frequency shifts due to the low stiffness, i.e., high sensitivity of the nanoscale oscillator, and can be measured with a rather

Generalized Hertz model for bimodal nanomechanical mapping

• Aleksander Labuda,
• Marta Kocuń,
• Waiman Meinhold,
• Deron Walters and
• Roger Proksch

Beilstein J. Nanotechnol. 2016, 7, 970–982, doi:10.3762/bjnano.7.89

• results in independent measures of nanomechanical properties by both eigenmodes while imaging. Notably, the fact that the weight function of the second eigenmode increases drastically as the tip approaches the sample, as seen in Figure 3f, explains the high sensitivity and increased spatial resolution of

• held fixed by the AGC. The fact that all three configurations lead to the same extracted Eeff suggests that the small-amplitude limit for the second mode was fulfilled. Sensitivity of bimodal AFM The high sensitivity of bimodal AFM was predicted in the theory described in Section ‘Bimodal interaction

• a small-amplitude second eigenmode into the measurement: it provides a high-sensitivity channel of information, without disrupting the measurement as explained in the previous section. Error from binomial approximation The error introduced by the approximation that allowed the analytical closed

Understanding interferometry for micro-cantilever displacement detection

• Alexander von Schmidsfeld,
• Tobias Nörenberg,
• Matthias Temmen and
• Michael Reichling

Beilstein J. Nanotechnol. 2016, 7, 841–851, doi:10.3762/bjnano.7.76

• smallest fiber–cantilever gap allows for displacement detection with a very low detection-system noise floor of promising a high sensitivity in force detection even for the relatively stiff cantilevers used in the present study. Apparently, the system noise is affected by opto-mechanical coupling and we

Highly compact refractive index sensor based on stripe waveguides for lab-on-a-chip sensing applications

• Chamanei Perera,
• Kristy Vernon,
• Elliot Cheng,
• Juna Sathian,
• Esa Jaatinen and
• Timothy Davis

Beilstein J. Nanotechnol. 2016, 7, 751–757, doi:10.3762/bjnano.7.66

• ] are widely used techniques utilising plasmons to measure refractive index changes. SPR is the most widely used sensing technique. It provides high sensitivity with label-free detection. Most commercially available SPR sensors employ a prism configuration to excite SPs on a metal surface which makes

Gold nanoparticles covalently assembled onto vesicle structures as possible biosensing platform

• M. Fátima Barroso,
• M. Alejandra Luna,
• Juan S. Flores Tabares,
• Cristina Delerue-Matos,
• N. Mariano Correa,
• Fernando Moyano and
• Patricia G. Molina

Beilstein J. Nanotechnol. 2016, 7, 655–663, doi:10.3762/bjnano.7.58

• fulfil performance criteria such as high sensitivity and low limit of detection. In this context, vesicles can be used in the construction of biosensors as supporting film to coat Au or Ag electrodes [3]. Self-assembly of nanoparticles onto organised systems combines the advantages of nanomaterials

Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection

• Dinusha N. Udukala,
• Hongwang Wang,
• Sebastian O. Wendel,
• Aruni P. Malalasekera,
• Thilani N. Samarakoon,
• Asanka S. Yapa,
• Gayani Abayaweera,
• Matthew T. Basel,
• Pamela Maynez,
• Raquel Ortega,
• Yubisela Toledo,
• Leonie Bossmann,
• Colette Robinson,
• Katharine E. Janik,
• Olga B. Koper,
• Ping Li,
• Massoud Motamedi,
• Daniel A. Higgins,
• Gary Gadbury,
• Gaohong Zhu,
• Deryl L. Troyer and
• Stefan H. Bossmann

Beilstein J. Nanotechnol. 2016, 7, 364–373, doi:10.3762/bjnano.7.33

• the use of dextran as anticoagulant [42]. The requirement of only a very low volume of serum for performing meaningful enzyme activity measurements is a definite advantage of the very high sensitivity of the nanoplatforms for protease detection, which originates from the concurrent utilization of SEM

Mismatch detection in DNA monolayers by atomic force microscopy and electrochemical impedance spectroscopy

• Maryse D. Nkoua Ngavouka,
• Pietro Capaldo,
• Elena Ambrosetti,
• Giacinto Scoles,
• Loredana Casalis and
• Pietro Parisse

Beilstein J. Nanotechnol. 2016, 7, 220–227, doi:10.3762/bjnano.7.20

• strategies [22] might improve sensitivity further possibly circumventing the annealing step. Electrochemical impedance spectroscopy-based assay Despite the high sensitivity, the AFM assay does not allow, at the moment, for a real-time investigation of binding events. In order to overcome such limitations, we

• multiplexing. Ultimate sensitivity has been demonstrated for these arrays (100 pM, [41]), making them overall amenable to less invasive diagnostic analysis with a sensible reduction of the volume of the analyte till single cell [26]. Finally, our electrochemical measurements combine high sensitivity with real

Evaluation of gas-sensing properties of ZnO nanostructures electrochemically doped with Au nanophases

• Elena Dilonardo,
• Michele Penza,
• Marco Alvisi,
• Cinzia Di Franco,
• Francesco Palmisano,
• Luisa Torsi and
• Nicola Cioffi

Beilstein J. Nanotechnol. 2016, 7, 22–31, doi:10.3762/bjnano.7.3

• active layer in low-cost chemiresistive gas sensors, due to their high sensitivity to gaseous analytes and easy production. The gas-sensing mechanism of MOS-based gas sensors is based on receptor and transducer functions [3]. Specifically, the first regards the recognition of a gaseous analyte by an

Blue and white light emission from zinc oxide nanoforests

• Nafisa Noor,
• Luca Lucera,
• Thomas Capuano,
• Venkata Manthina,
• Alexander G. Agrios,
• Helena Silva and
• Ali Gokirmak

Beilstein J. Nanotechnol. 2015, 6, 2463–2469, doi:10.3762/bjnano.6.255

• electrical contact (Figure 1c). The probe separation for all electrical measurements was ≈10–15 µm. Either a high-sensitivity 1080p HD camcorder with a frame rate of 60 fps (Sony, HDR-CX160) or a high-speed camera with a maximum of 1200 fps (Casio, EX-F1) was connected to the microscope head for imaging

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

• [136][137]. In the field of nanotechnology, the real-time monitoring of size and shapes of nanostructures is of high importance even though it is very challenging. There are reports on developing innovative systems, such as grazing-incidence small-angle X-ray scattering setup that showed a high

• sensitivity to control the required parameters of the production of NPs [138]. Inherently safer chemistry: All types of required substances for a chemical process should be selected so that the all hazards and risks of the system, such as toxicity, flammability and explosivity are minimized to prevent