Beilstein J. Nanotechnol.2010,1, 142–154, doi:10.3762/bjnano.1.17
][21][22][23][24][25]. A variety of chemical methods, ranging from traditional wet chemistry to high-temperature thermaldecomposition, have been employed to synthesize MNPs. Colloidal iron oxide nanoparticles, which are used as clinical magnetic resonance imaging (MRI) contrast agents, are generally
, magnetization can vary significantly among nanoparticles of similar sizes.
More recently, high quality MNPs have been prepared through thermaldecomposition of organometallic precursors, in nonhydrolytic organic solutions containing surfactants [15][16][27][28][29]. Monomers are generated via high-temperature
thermaldecomposition of precursors. Above a supersaturation level, these monomers then aggregate to induce nucleation and nanoparticle growth. By tuning the growth conditions during this procedure (such as precursor choice, monomer concentration, growth temperature and time), it is possible to control
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Figure 1:
DMR assay configurations with magnetic nanoparticles (MNPs). (a) Magnetic relaxation switching (MRS...
Beilstein J. Nanotechnol.2010,1, 101–107, doi:10.3762/bjnano.1.12
.
Experimental
Iron oxide NPs were prepared by thermaldecomposition of metal-oleate complexes [40]. As-prepared, particles with mean diameter of 20 nm and 7% size distribution were coated with a ~2 nm thick layer of oleic acid and dissolved in toluene. The NP dispersion, with a concentration of approximately 50
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Figure 1:
AFM (a) and SEM (b) images showing the self-assembly of the NPs in a close-packed hexagonal structu...