Vibration analysis and pull-in instability behavior in a multiwalled piezoelectric nanosensor with fluid flow conveyance

• Sayyid H. Hashemi Kachapi

Beilstein J. Nanotechnol. 2020, 11, 1072–1081, doi:10.3762/bjnano.11.92

• , pharmaceutical, agricultural, environmental, advanced materials, chemical science, physics, electronics, information technology, biomedical and medical fields [1][2][3][4][5][6][7][8][9][10]. Due to this extended use of nanosensors, especially piezoelectric nanosensors in vibration devices, mathematical models

Uniform Fe₃O₄/Gd₂O₃-DHCA nanocubes for dual-mode magnetic resonance imaging

• Miao Qin,
• Yueyou Peng,
• Mengjie Xu,
• Hui Yan,
• Yizhu Cheng,
• Xiumei Zhang,
• Di Huang,
• Weiyi Chen and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2020, 11, 1000–1009, doi:10.3762/bjnano.11.84

• Miao Qin Yueyou Peng Mengjie Xu Hui Yan Yizhu Cheng Xiumei Zhang Di Huang Weiyi Chen Yanfeng Meng Research Center for Nano-Biomaterials & Regenerative Medicine, Department of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China

• Department of MRI, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, Shanxi 030009, China Institute of Biomedical Engineering, Shanxi Key Laboratory of Materials Strength & Structural Impact, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China 10.3762/bjnano.11.84 Abstract The

Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties

• Marta Bartel,
• Katarzyna Markowska,
• Marcin Strawski,
• Krystyna Wolska and
• Maciej Mazur

Beilstein J. Nanotechnol. 2020, 11, 620–630, doi:10.3762/bjnano.11.49

• , optoelectronic elements and biomedical devices [18][19]. Polystyrene beads are also a versatile material that can be quite easily functionalized with sulfonic groups. The particles are incubated with concentrated sulfuric acid at elevated temperature, which results in gradual etching of their surface. Through

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• Varsha Sharma Anandhakumar Sundaramurthy Department of Biomedical Engineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India Department of Physics and

• ability to disintegrate at physiological pH makes them more versatile for biomedical applications. Crosslinking and covalent interactions Unlike electrostatic and hydrogen bonding interactions, the covalently linked multilayers provide a more robust way to manipulate permeability, stability and mechanical

Evolution of Ag nanostructures created from thin films: UV–vis absorption and its theoretical predictions

• Robert Kozioł,
• Marcin Łapiński,
• Paweł Syty,
• Damian Koszelow,
• Wojciech Sadowski,
• Józef E. Sienkiewicz and
• Barbara Kościelska

Beilstein J. Nanotechnol. 2020, 11, 494–507, doi:10.3762/bjnano.11.40

• Physics and Mathematics, Department of Theoretical Physics and Quantum Information, Gdansk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdansk, Poland Faculty of Electronics, Telecommunication and Informatics, Department of Biomedical Engineering, Gdansk University of Technology, Gabriela

Nanoarchitectonics: bottom-up creation of functional materials and systems

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2020, 11, 450–452, doi:10.3762/bjnano.11.36

• synthesis; nanoarchitectonics; nanotechnology; self-assembly; supramolecular; Given the significant and time-critical problems of energy shortage, environmental protection, and biomedical issues, the creation of new functional materials and systems for efficient energy production and storage [1][2

• ], environmental remediation with sensitive pollutant detection [3][4], and biological and biomedical applications [5][6] is a crucial matter. In addition to the intrinsic functionality of bulk materials, control of their internal structure on the nanometer-scale is realized to be increasingly important to obtain

• hydroxide/sepiolite hybrids [31], and cell surface engineering with halloysite-doped silica cell imprints for shape recognition of human cells [32]. In another example, magnetic nanoparticles were attached to microbubble shells for enhanced biomedical imaging [33]. In a final example, the detection of the

Nanoparticles based on the zwitterionic pillar[5]arene and Ag⁺: synthesis, self-assembly and cytotoxicity in the human lung cancer cell line A549

• Dmitriy N. Shurpik,
• Denis A. Sevastyanov,
• Pavel V. Zelenikhin,
• Pavel L. Padnya,
• Vladimir G. Evtugyn,
• Yuriy N. Osin and
• Ivan I. Stoikov

Beilstein J. Nanotechnol. 2020, 11, 421–431, doi:10.3762/bjnano.11.33

• and 2D biomedical coatings. Keywords: cytotoxicity; macrocyclic receptors; nanoparticles; pillar[5]arene; self-assembly; silver; Introduction The first use of silver (Ag) as a medicine dates back to Hippocrates, who used it as an antibacterial agent for the treatment of ulcers [1]. Over the past

• biomedical properties of the resulting nanoscale particles that do not contain Ag–Ag bonds [14]. However, the main problem is the fact that macrocyclic hosts have low solubility in water, which significantly narrows their application [15][16][17][18][19][20]. Therefore, we propose to use water-soluble

• concentration of silver ions of 30 μM and 55% for a concentration of silver ions of 40 μM. The results can be used to create new antibacterial materials and 2D biomedical coatings. Experimental 1H NMR, 13C and 2D NOESY NMR spectra were obtained on a Bruker Avance-400 spectrometer (13С{1H} – 100 MHz and 1H and

Brome mosaic virus-like particles as siRNA nanocarriers for biomedical purposes

• Alfredo Nuñez-Rivera,
• Pierrick G. J. Fournier,
• Danna L. Arellano,
• Ana G. Rodriguez-Hernandez,
• Rafael Vazquez-Duhalt and
• Ruben D. Cadena-Nava

Beilstein J. Nanotechnol. 2020, 11, 372–382, doi:10.3762/bjnano.11.28

• , handling, and simple structure, plant viruses are attractive for some biomedical applications. Plant bromoviruses, such as the brome mosaic virus (BMV), are viral bionanoparticles that have been proposed as platforms for drug delivery in different therapies, and as diagnostic imaging agents in cancer [18

• properties of biomedical interest are demonstrated, such as biocompatibility, tumor cell internalization, and their efficiency as nanocarriers for siRNA delivery. In addition, the capacity of the BMV and CCMV viruses to modulate the immune response in vitro was also analyzed. Results and Discussion Cell

Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy

• Gayathri Kandasamy,
• Elena N. Danilovtseva,
• Vadim V. Annenkov and
• Uma Maheswari Krishnan

Beilstein J. Nanotechnol. 2020, 11, 354–369, doi:10.3762/bjnano.11.26

• ]. Several studies have explored the potential biomedical applications of PVI and its derivatives. Pullulan-grafted poly(1-vinylimidazole) was found complex anionic citrate and tripolyphosphate effectively in acidic medium via the imidazole moiety [8]. The catalytic properties of poly(1-vinylimidazole) due

Facile biogenic fabrication of hydroxyapatite nanorods using cuttlefish bone and their bactericidal and biocompatibility study

• Satheeshkumar Balu,
• Manisha Vidyavathy Sundaradoss,
• Swetha Andra and
• Jaison Jeevanandam

Beilstein J. Nanotechnol. 2020, 11, 285–295, doi:10.3762/bjnano.11.21

• , the hazardous chemicals involved in the synthesis process, which are toxic to healthy cells, is the primary limitation to employ these materials in widespread biomedical and environmental applications. Thus, the nontoxic, ecologically friendly preparation of Hap has received considerable attention in

• biomedical field [8][9]. Hence, natural calcium phosphate from marine organisms plays a major role in recent developments of Hap for use in biomedical applications. Cuttlefish (Sepia officinalis) is an important marine food that is available for human consumption, and tons of cuttlefish bones are produced as

• waste material every day by the marine food industry across the world, resulting in environmental contamination [10]. In ancient times, cuttlefish bone powder was used as biomedicine in China and India for oral health and is proven to be completely suitable for biomedical applications [11]. Further, the

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• , sensors, molecular or nanoelectronics, diagnostics, drug delivery, and biomedical sciences. The remarkable molecular fidelity and sequence-specific molecular recognition make DNA the ideal candidate in the scheme of molecular architectonics to design and construct functional DNA nanoarchitectures. In this

Fully amino acid-based hydrogel as potential scaffold for cell culturing and drug delivery

• Dávid Juriga,
• Evelin Sipos,
• Orsolya Hegedűs,
• Gábor Varga,
• Miklós Zrínyi,
• Krisztina S. Nagy and
• Angéla Jedlovszky-Hajdú

Beilstein J. Nanotechnol. 2019, 10, 2579–2593, doi:10.3762/bjnano.10.249

• ]. Among them, synthetic, amino acid-based polymers attract particular attention due to their tunable properties and the structural similarity to the native ECM [26]. The poly(amino acid)s being tested for biomedical applicability can be classified into three groups: anionic, cationic and neutral poly

• ]. Moreover, our research group demonstrated previously that hydrogels based on the anionic poly(aspartic acid) (PASP) are also well-suited for tissue engineering purposes [25]. Another field of potential biomedical applications of poly(amino acid)s is drug delivery. Poly(amino acid)-based microcarriers can

• degradation properties of the gels containing LYS and CYS at different ratios were investigated since these attributes are crucial for biomedical applications. The swelling degree was determined at different pH values and under redox conditions. For biocompatibility studies, cell viability tests were carried

Frontiers in pharmaceutical nanotechnology

• Matthias G. Wacker

Beilstein J. Nanotechnol. 2019, 10, 2538–2540, doi:10.3762/bjnano.10.244

• is a very dynamic and evolving research area that integrates a wide variety of disciplines such as chemical, biological and biomedical science. At the frontier of knowledge, nanoparticles, exosomes and even more advanced drug delivery systems [1] blur the line between drug discovery and formulation

Small protein sequences can induce cellular uptake of complex nanohybrids

• Jan-Philip Merkl,
• Malak Safi,
• Christian Schmidtke,
• Fadi Aldeek,
• Johannes Ostermann,
• Tatiana Domitrovic,
• Sebastian Gärtner,
• John E. Johnson,
• Horst Weller and
• Hedi Mattoussi

Beilstein J. Nanotechnol. 2019, 10, 2477–2482, doi:10.3762/bjnano.10.238

• nanostructures made of more than one component nanomaterial, combined with biomolecules is a highly sought goal in biomedical science, and can find applications in multimodal imaging and therapeutics [1][2]. Although interest in developing such hybrid nanostructures by, for example, combining plasmonic and

pH-Controlled fluorescence switching in water-dispersed polymer brushes grafted to modified boron nitride nanotubes for cellular imaging

• Saban Kalay,
• Yurij Stetsyshyn,
• Volodymyr Donchak,
• Khrystyna Harhay,
• Ostap Lishchynskyi,
• Halyna Ohar,
• Yuriy Panchenko,
• Stanislav Voronov and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2019, 10, 2428–2439, doi:10.3762/bjnano.10.233

• commonly used labels is fluorescein [37][38][39][40][41][42]. In biomedical applications, fluorescein has several advantages over other dyes such as nontoxicity, high water solubility, and pH responsivity. Fluorescein demonstrates a high fluorescence efficiency at basic pH values but becomes nonfluorescent

• good dispersibility in water and their fluorescent properties make them excellent candidates for biomedical applications. pH-Responsive fluorescent properties of P(AA-co-FA)-functionalized BNNTs Depending on pH, fluorescein can exist as a cation, monoanion, dianion, amphoion, neutral quinoid structure

• )-functionalized BNNTs is excellent and they can potentially be used in biomedical applications. We plan to continue to explore this new hybrid in our future studies not only as a pH-switchable label but also as “smart” surfaces and nanocarriers. Conclusion pH-Switchable, fluorescent, hybrid, water-dispersed

Deterministic placement of ultra-bright near-infrared color centers in arrays of silicon carbide micropillars

• Stefania Castelletto,
• Abdul Salam Al Atem,
• Faraz Ahmed Inam,
• Hans Jürgen von Bardeleben,
• Sophie Hameau,
• Ahmed Fahad Almutairi,
• Gérard Guillot,
• Shin-ichiro Sato,
• Alberto Boretti and
• Jean Marie Bluet

Beilstein J. Nanotechnol. 2019, 10, 2383–2395, doi:10.3762/bjnano.10.229

• ) [53]. Here, we focus on the enhancement of the emission of the VSi, VSiVC and NCVSi/4H-SiC platforms aiming at increasing the photon collection efficiency of many emitters to improve the resolution of quantum sensing in biomedical imaging applications due to the favorable emission in the near-infrared

Atomic force acoustic microscopy reveals the influence of substrate stiffness and topography on cell behavior

• Yan Liu,
• Li Li,
• Xing Chen,
• Ying Wang,
• Meng-Nan Liu,
• Jin Yan,
• Liang Cao,
• Lu Wang and
• Zuo-Bin Wang

Beilstein J. Nanotechnol. 2019, 10, 2329–2337, doi:10.3762/bjnano.10.223

• an effective tool to measure soft materials such as biomedical tissues and polymers [18]. A number of research groups have reported that the AFAM method can characterize mechanical properties of buried structures. For example, the influence of the thickness on the elastic properties of porous

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

• Sabrina Barbosa de Souza Ferreira,
• Gustavo Braga,
• Évelin Lemos Oliveira,
• Jéssica Bassi da Silva,
• Hélen Cássia Rosseto,
• Lidiane Vizioli de Castro Hoshino,
• Mauro Luciano Baesso,
• Wilker Caetano,
• Craig Murdoch,
• Helen Elizabeth Colley and
• Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

• characteristics beneficial for pharmaceutical and biomedical use [1]. P407 is a non-ionic block copolymer with polypropylene oxide (PPO) and polyethylene oxide (PEO) segments, which can display thermoresponsive properties forming nanometer-sized micelles, hydrogels and lyotropic liquid crystals [2][3]. The

Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration

• Nashrawan Lababidi,
• Valentin Sigal,
• Aljoscha Koenneke,
• Konrad Schwarzkopf,
• Andreas Manz and
• Marc Schneider

Beilstein J. Nanotechnol. 2019, 10, 2280–2293, doi:10.3762/bjnano.10.220

• applications. Keywords: curcumin; human pulmonary mucus; microfluidics; muco-penetrating nanoparticles; nanomedicine; permeability; PLGA nanoparticles; Introduction In the last decades, the application of nanotechnology in medicine has gained significant attention, especially in the biomedical field for

Targeted therapeutic effect against the breast cancer cell line MCF-7 with a CuFe₂O₄/silica/cisplatin nanocomposite formulation

• B. Rabindran Jermy,
• Vijaya Ravinayagam,
• Widyan A. Alamoudi,
• Dana Almohazey,
• Hatim Dafalla,
• Lina Hussain Allehaibi,
• Abdulhadi Baykal,
• Muhammet S. Toprak and
• Thirunavukkarasu Somanathan

Beilstein J. Nanotechnol. 2019, 10, 2217–2228, doi:10.3762/bjnano.10.214

• multifunctional biomedical applications. The crystalline phase, morphology, magnetization, and coordination environment of various spinel species were characterized using X-ray diffraction (XRD), BET surface area measurements, vibrating sample magnetometry (VSM), diffuse reflectance UV–vis spectroscopy (DR UV–vis

Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials

• Stefania Ordanini,
• Wanda Celentano,
• Anna Bernardi and
• Francesco Cellesi

Beilstein J. Nanotechnol. 2019, 10, 2192–2206, doi:10.3762/bjnano.10.212

• ]. In addition, the high surface area of spherical self-assembled structures can confer glycopolymers a high affinity towards lectins [18]. Among different synthetic macromolecules used in biomedical applications, copolymers based on poly(ethylene glycol) (PEG) and poly(ε-caprolactone) (PCL) are found

Nitrogen-vacancy centers in diamond for nanoscale magnetic resonance imaging applications

• Alberto Boretti,
• Lorenzo Rosa,
• Jonathan Blackledge and
• Stefania Castelletto

Beilstein J. Nanotechnol. 2019, 10, 2128–2151, doi:10.3762/bjnano.10.207

• -suited for medical applications and must undergo the hyperpolarization process. Some methods are proposed in [18], albeit not yet applied in biomedical samples, using nanodiamonds (NDs) as a contrast agent to improve the SNR in conventional MRI. While NDs have been recently applied as theranostic

• preparation. Specifically, NV forms in both bulk and ND – this option introduces more opportunity in terms of applications, even if the ND NV magnetic sensing technology is less developed. A review of the superior properties of diamond nanomaterials and the NV centers, as well as their uses in biomedical

• modulated with a magnetic field giving increased sensitivity. As bioimaging probes, they are versatile, cost-effective and easily functionalized, in addition to being easy to coat with silica for biomedical applications. Background-free imaging, both in vivo and in vitro, is achieved by applying an

Microbubbles decorated with dendronized magnetic nanoparticles for biomedical imaging: effective stabilization via fluorous interactions

• Da Shi,
• Justine Wallyn,
• Dinh-Vu Nguyen,
• Francis Perton,
• Delphine Felder-Flesch,
• Sylvie Bégin-Colin,
• Mounir Maaloum and
• Marie Pierre Krafft

Beilstein J. Nanotechnol. 2019, 10, 2103–2115, doi:10.3762/bjnano.10.205

Review of advanced sensor devices employing nanoarchitectonics concepts

• Katsuhiko Ariga,
• Tatsuyuki Makita,
• Masato Ito,
• Taizo Mori,
• Shun Watanabe and
• Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

• detection of various risks [9][10][11], environmental remediation including pollution problems [12][13][14], energy production [15][16][17], energy and electricity storage [18][19][20], device technologies [21][22][23], and biomedical treatment [24][25][26][27], and the targets must be detected with high

• ][71], biological investigation [72][73][74][75], and biomedical applications [76][77][78]. As compared with simple self-assembly processes, nanoarchitectonics is advantageous for architecting hierarchical structures and interfacing between materials and devices. In addition, the fabrication of sensor

• could be applicable for demands requiring the evaluation of small normal pressures even on dynamic surfaces such as natural tissues and is expected to be useful for in situ biomedical digital monitoring, such as palpation for breast cancer. Triboelectric nanogenerators to convert mechanical energy to

Gold-coated plant virus as computed tomography imaging contrast agent

• Alaa A. A. Aljabali,
• Mazhar S. Al Zoubi,
• Khalid M. Al-Batanyeh,
• Ali Al-Radaideh,
• Mohammad A. Obeid,
• Abeer Al Sharabi,
• Walhan Alshaer,
• Bayan AbuFares,
• Tasnim Al-Zanati,
• Murtaza M. Tambuwala,
• Naveed Akbar and
• David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

• agent offer a fast scan time (less than 2 min), low cost, and biocompatibility and allow for high-resolution imaging with ca. 150 Hounsfield units (HU). The Au-CPMV surface was further modified allowing for the incorporation of targeting molecules of specific cell types. Keywords: biomedical imaging

• the surface functionalities allows for the use of such particles in biomedical applications. The Au-CPMV particles reported here exhibit excellent stability over at least almost a year. No visible aggregation nor changes in particles size was observed in samples stored at 4 °C. Their surface can be