Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• magnetic nanoparticles (MNPs) have recently received considerable attention, since they offer unique advantages over traditional detection methods. Specifically, because biological samples exhibit negligible magnetic background, MNPs can be used to obtain highly sensitive measurements in turbid samples

• wide range of targets including DNA/mRNA, proteins, small molecules/drugs, bacteria, and tumor cells. More recently, the development of miniaturized, chip-based NMR detector systems has served to further enhance DMR technology [14][15][16]. Such detectors can perform highly sensitive measurements on

Preparation and characterization of supported magnetic nanoparticles prepared by reverse micelles

• Ulf Wiedwald,
• Luyang Han,
• Johannes Biskupek,
• Ute Kaiser and
• Paul Ziemann

Beilstein J. Nanotechnol. 2010, 1, 24–47, doi:10.3762/bjnano.1.5

• the medical field [7], e.g., in hyperthermia [8], contrast enhancing in magnetic resonance imaging [9][10] or the use as cell markers [9] which in-turn can be read out by highly-sensitive devices like TMR-sensors [11]. Moreover, magnetic NPs are thought to improve a variety of catalytic reactions [12