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Search for "medical" in Full Text gives 347 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Evolution of Ag nanostructures created from thin films: UV–vis absorption and its theoretical predictions

  • Robert Kozioł,
  • Marcin Łapiński,
  • Paweł Syty,
  • Damian Koszelow,
  • Wojciech Sadowski,
  • Józef E. Sienkiewicz and
  • Barbara Kościelska

Beilstein J. Nanotechnol. 2020, 11, 494–507, doi:10.3762/bjnano.11.40

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  • : dewetting; finite-difference time-domain (FDTD) method; plasmon resonance; silver (Ag) nanostructures; thin films; UV–vis absorption; Introduction In the last decade there has been significant development in sensor-related research regarding the application in optical, medical or biological areas [1][2][3
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Published 25 Mar 2020

Preparation and in vivo evaluation of glyco-gold nanoparticles carrying synthetic mycobacterial hexaarabinofuranoside

  • Gennady L. Burygin,
  • Polina I. Abronina,
  • Nikita M. Podvalnyy,
  • Sergey A. Staroverov,
  • Leonid O. Kononov and
  • Lev A. Dykman

Beilstein J. Nanotechnol. 2020, 11, 480–493, doi:10.3762/bjnano.11.39

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  • Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), Institutsky per. 9, Dolgoprudnyi, Moscow Region, 141701, Russia 10.3762/bjnano.11.39 Abstract A number of bacterial glycans are specific markers for the detection and the
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Published 19 Mar 2020

Nanoparticles based on the zwitterionic pillar[5]arene and Ag+: synthesis, self-assembly and cytotoxicity in the human lung cancer cell line A549

  • Dmitriy N. Shurpik,
  • Denis A. Sevastyanov,
  • Pavel V. Zelenikhin,
  • Pavel L. Padnya,
  • Vladimir G. Evtugyn,
  • Yuriy N. Osin and
  • Ivan I. Stoikov

Beilstein J. Nanotechnol. 2020, 11, 421–431, doi:10.3762/bjnano.11.33

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  • thousands of years, the use of this metal has grown into an entire industry [1]. A separate area of this industry is the use of silver nanoparticles (AgNPs), which are the source of Ag+ ions in many commercial products, such as food packaging, odor-resistant fabrics, household appliances and medical devices
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Published 05 Mar 2020

Understanding nanoparticle flow with a new in vitro experimental and computational approach using hydrogel channels

  • Armel Boutchuen,
  • Dell Zimmerman,
  • Abdollah Arabshahi,
  • John Melnyczuk and
  • Soubantika Palchoudhury

Beilstein J. Nanotechnol. 2020, 11, 296–309, doi:10.3762/bjnano.11.22

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  • , United States Department of Chemistry, Clark Atlanta University, Georgia 30314, United States 10.3762/bjnano.11.22 Abstract Nanoparticles (NPs) are considered as one of the most promising drug delivery vehicles and a next-generation solution for current medical challenges. In this context, variables
  • ; Introduction Current research increasingly highlight the importance of drug delivery systems in engineering new solutions to our medical challenges [1][2][3]. A drug delivery agent should be biocompatible, easily administered to the patient, and capable of carrying the drug to the disease site before
  • enhanced circulation and controlled delivery to the disease sites compared to conventional drug formulations. In the context of achieving next-generation medical solutions with NPs, an in vitro technique that can mimic or visualize the transport of these NP-based drugs through vascular networks will be a
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Published 06 Feb 2020

Anomalous current–voltage characteristics of SFIFS Josephson junctions with weak ferromagnetic interlayers

  • Tairzhan Karabassov,
  • Anastasia V. Guravova,
  • Aleksei Yu. Kuzin,
  • Elena A. Kazakova,
  • Shiro Kawabata,
  • Boris G. Lvov and
  • Andrey S. Vasenko

Beilstein J. Nanotechnol. 2020, 11, 252–262, doi:10.3762/bjnano.11.19

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  • , Moscow State Pedagogical University, 119992 Moscow, Russia Sechenov First Moscow State Medical University, 119991 Moscow, Russia National Institute of Advanced Industrial Science and Technology,1-1-1 Umezono, Tsukuba, Ibaraki 305-8563, Japan I.E. Tamm Department of Theoretical Physics, P.N. Lebedev
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Published 23 Jan 2020

Internalization mechanisms of cell-penetrating peptides

  • Ivana Ruseska and
  • Andreas Zimmer

Beilstein J. Nanotechnol. 2020, 11, 101–123, doi:10.3762/bjnano.11.10

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  • medical research [7]. Compared to the other translocation techniques mentioned, CPPs are capable of entering the cells in a noninvasive manner, they do not destroy the integrity of the cellular membranes and are considered highly efficient and safe. Thus, they provide new avenues for research and
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Published 09 Jan 2020

Fully amino acid-based hydrogel as potential scaffold for cell culturing and drug delivery

  • Dávid Juriga,
  • Evelin Sipos,
  • Orsolya Hegedűs,
  • Gábor Varga,
  • Miklós Zrínyi,
  • Krisztina S. Nagy and
  • Angéla Jedlovszky-Hajdú

Beilstein J. Nanotechnol. 2019, 10, 2579–2593, doi:10.3762/bjnano.10.249

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  • (amino acid); poly(aspartic acid); polymer; Introduction The number of medical applications of polymer hydrogels increased substantially during the last decades due to their similarity to soft tissues [1][2][3]. Polymer hydrogels possess properties of solid materials such as deformability and rigidity
  • well as biocompatibility and biodegradability are also fundamental features of polymers developed for numerous medical applications [11][12]. Polymer hydrogels are capable of releasing physically entrapped drug molecules. The release kinetics of the loaded drug molecules depend significantly on the
  • ]. In the last decades, the interest of scientists in PASP-based hydrogels increased significantly due to their potential applications in medical, pharmaceutical and environmental fields [25][34][41][42][43][44]. Several publications can be found concerning different types of cross-linkers to prepare
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Published 27 Dec 2019

Frontiers in pharmaceutical nanotechnology

  • Matthias G. Wacker

Beilstein J. Nanotechnol. 2019, 10, 2538–2540, doi:10.3762/bjnano.10.244

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  • materials with a long history of medical use [12]. Pharmaceutical nanotechnology is not limited to translational research but, after many years of trial and error, we have to accept that reliable pharmacological and toxicological effects are a key element of industrial formulation development. Understanding
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Published 17 Dec 2019

Label-free highly sensitive probe detection with novel hierarchical SERS substrates fabricated by nanoindentation and chemical reaction methods

  • Jingran Zhang,
  • Tianqi Jia,
  • Yongda Yan,
  • Li Wang,
  • Peng Miao,
  • Yimin Han,
  • Xinming Zhang,
  • Guangfeng Shi,
  • Yanquan Geng,
  • Zhankun Weng,
  • Daniel Laipple and
  • Zuobin Wang

Beilstein J. Nanotechnol. 2019, 10, 2483–2496, doi:10.3762/bjnano.10.239

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  • Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150010, P.R. China 5Department of Gynaecology, No. 3 Subsidiary Hospital, Harbin Medical University, Harbin, Heilongjiang, 150040, P.R. China 10.3762/bjnano.10.239 Abstract Nanostructures have been widely employed in
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Published 13 Dec 2019

Atomic force acoustic microscopy reveals the influence of substrate stiffness and topography on cell behavior

  • Yan Liu,
  • Li Li,
  • Xing Chen,
  • Ying Wang,
  • Meng-Nan Liu,
  • Jin Yan,
  • Liang Cao,
  • Lu Wang and
  • Zuo-Bin Wang

Beilstein J. Nanotechnol. 2019, 10, 2329–2337, doi:10.3762/bjnano.10.223

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  • Manufacturing of China, Changchun University of Science and Technology, Changchun 130022, China Computer Department, Changchun Medical College, Changchun 130031, China JR3CN & IRAC, University of Bedfordshire, Luton LU1 3JU, UK 10.3762/bjnano.10.223 Abstract The stiffness and the topography of the substrate at
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Published 26 Nov 2019

Dynamics of superparamagnetic nanoparticles in viscous liquids in rotating magnetic fields

  • Nikolai A. Usov,
  • Ruslan A. Rytov and
  • Vasiliy A. Bautin

Beilstein J. Nanotechnol. 2019, 10, 2294–2303, doi:10.3762/bjnano.10.221

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  • (AMF) of frequency f = 100–500 kHz and amplitude H0 = 100–200 Oe. This would allow the tumor temperature to be maintained at about 42 °C if a magnetic nanoparticle assembly were capable to absorb efficiently the energy of the alternating magnetic field. According to a number of medical indications [1
  • frequencies and amplitudes is recommended for medical reasons to be used in magnetic hyperthermia [49][50]. In the first mode existing in domain I in Figure 2 at low and moderate RMF frequencies the vectors and rotate in unison around the Z-axis with the RMF frequency. However, there are constant phase
  • insignificant. Moreover, the use of variable magnetic fields of large amplitude requires the generation of strong electric currents, which may be unsafe in a medical clinic. In this regard, it seems more promising to use RMFs of moderate amplitude, H0 = 100–120 Oe, but at frequencies of about 400–600 kHz in
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Published 22 Nov 2019

Targeted therapeutic effect against the breast cancer cell line MCF-7 with a CuFe2O4/silica/cisplatin nanocomposite formulation

  • B. Rabindran Jermy,
  • Vijaya Ravinayagam,
  • Widyan A. Alamoudi,
  • Dana Almohazey,
  • Hatim Dafalla,
  • Lina Hussain Allehaibi,
  • Abdulhadi Baykal,
  • Muhammet S. Toprak and
  • Thirunavukkarasu Somanathan

Beilstein J. Nanotechnol. 2019, 10, 2217–2228, doi:10.3762/bjnano.10.214

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  • B. Rabindran Jermy Vijaya Ravinayagam Widyan A. Alamoudi Dana Almohazey Hatim Dafalla Lina Hussain Allehaibi Abdulhadi Baykal Muhammet S. Toprak Thirunavukkarasu Somanathan Department of Nano-Medicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal
  • University, P.O. Box 1982, 31441 Dammam, Saudi Arabia Deanship of Scientific Research & Department of Nano-Medicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, 31441 Dammam, Saudi Arabia Department of Neuroscience Research, Institute for
  • Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, 31441 Dammam, Saudi Arabia Department of Stem Cell Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, 31441 Dammam, Saudi Arabia College of Engineering
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Published 12 Nov 2019

BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products

  • Florence Olechowski,
  • Rainer H. Müller and
  • Sung Min Pyo

Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208

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  • inclusion; nanostructured lipid carriers (NLCs); penetration enhancement; skin occlusion; SmartLipids; solid lipid nanoparticles (SLNs); Introduction To meet the increasing expectations and demands of consumers in personal care and cosmetics, as well of patients in medical care, dermal delivery systems are
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Published 04 Nov 2019

Nitrogen-vacancy centers in diamond for nanoscale magnetic resonance imaging applications

  • Alberto Boretti,
  • Lorenzo Rosa,
  • Jonathan Blackledge and
  • Stefania Castelletto

Beilstein J. Nanotechnol. 2019, 10, 2128–2151, doi:10.3762/bjnano.10.207

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  • MRI as a medical technique, with the purpose of imaging soft body tissues and organs through the excitation of their atomic nuclei with high-frequency radio pulses and the measurement of the response in a strong magnetic field. Recent research has included using MRI for nanoscale imaging, enabling
  • with high-spectral-resolution NMR spectroscopy is presented in [13]. In terms of future commercial products that permit nano-MRI to be undertaken at hospitals and for medical research, it will inevitably be required that they be produced in a way that secures the best trade-off between cost and
  • 3D imaging by exploiting several spectral lines. Fourier/Hadamard transform techniques allow frequency–space multiplexing for faster measurement, where spatial information is recovered through Hadamard encoding and quadrature detection. Hyperpolarization is a novel functional medical imaging
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Published 04 Nov 2019

Microbubbles decorated with dendronized magnetic nanoparticles for biomedical imaging: effective stabilization via fluorous interactions

  • Da Shi,
  • Justine Wallyn,
  • Dinh-Vu Nguyen,
  • Francis Perton,
  • Delphine Felder-Flesch,
  • Sylvie Bégin-Colin,
  • Mounir Maaloum and
  • Marie Pierre Krafft

Beilstein J. Nanotechnol. 2019, 10, 2103–2115, doi:10.3762/bjnano.10.205

Graphical Abstract
  • conjunction with focused ultrasound, and under magnetic resonance imaging guidance, for achieving blood/brain and blood/tumor barrier crossing of drugs [11][12]. Medical MBs have a shell consisting of surfactants, phospholipids, or polymers and are usually stabilized by a fluorocarbon gas [13] that acts as an
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Published 31 Oct 2019

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

  • Sebastian Pieper,
  • Hannah Onafuye,
  • Dennis Mulac,
  • Jindrich Cinatl Jr.,
  • Mark N. Wass,
  • Martin Michaelis and
  • Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 2062–2072, doi:10.3762/bjnano.10.201

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  • , University of Kent, Canterbury CT2 7NJ, United Kingdom Institute for Medical Virology, University Hospital, Goethe-University, Paul Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany 10.3762/bjnano.10.201 Abstract Background: Nanoparticles are under investigation as carrier systems for anticancer drugs
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Published 29 Oct 2019

Review of advanced sensor devices employing nanoarchitectonics concepts

  • Katsuhiko Ariga,
  • Tatsuyuki Makita,
  • Masato Ito,
  • Taizo Mori,
  • Shun Watanabe and
  • Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

Graphical Abstract
  • .) on the sensing area. The sensitivity of the nanoengineered sensors is easily tunable by adjusting geometry-related parameters. For practical uses, sensors are not always used in ideal conditions. Especially, their use in dynamic human life, including health monitoring and medical applications
  • to human life, medical, and health monitoring, the development of biosensors has received significant attention. For example, for the detection of bisphenol A, which is suspected as an endocrine disruptor, Piro et al. produced a nanoarchitectonic electrolyte-gated organic field-effect transistor with
  • signals with an amplification factor of 200. This idea can be expanded to various practical sensing demands such as temporal monitoring during medical surgery and long-term implantable monitoring. Ingebrandt and co-workers also reported biosensors to monitor electrophysiological activity of the cardiac
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Published 16 Oct 2019

Gold-coated plant virus as computed tomography imaging contrast agent

  • Alaa A. A. Aljabali,
  • Mazhar S. Al Zoubi,
  • Khalid M. Al-Batanyeh,
  • Ali Al-Radaideh,
  • Mohammad A. Obeid,
  • Abeer Al Sharabi,
  • Walhan Alshaer,
  • Bayan AbuFares,
  • Tasnim Al-Zanati,
  • Murtaza M. Tambuwala,
  • Naveed Akbar and
  • David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

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  • , Jordan Yarmouk University - Faculty of Medicine, Department of Basic Medical Sciences, Irbid, Jordan Yarmouk University - Faculty of Science, Department of Biological Sciences, Irbid, Jordan Hashemite University - Department of Medical Imaging, Zarqa, Jordan National Agricultural Research Center, Amman
  • aperture 0.6; Olympus). Images were taken using a back-illuminated electron multiplying charge-coupled camera (Andor Technology, Belfast, Northern Ireland) Computed tomography (CT) scanning Scanning was performed three times (different days) on a multi-slice GE CT (Optima CT660) scanner (GE MEDICAL SYSTEMS
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Published 07 Oct 2019

Magnetic properties of biofunctionalized iron oxide nanoparticles as magnetic resonance imaging contrast agents

  • Natalia E. Gervits,
  • Andrey A. Gippius,
  • Alexey V. Tkachev,
  • Evgeniy I. Demikhov,
  • Sergey S. Starchikov,
  • Igor S. Lyubutin,
  • Alexander L. Vasiliev,
  • Vladimir P. Chekhonin,
  • Maxim A. Abakumov,
  • Alevtina S. Semkina and
  • Alexander G. Mazhuga

Beilstein J. Nanotechnol. 2019, 10, 1964–1972, doi:10.3762/bjnano.10.193

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  • ), MIPT, 141701 Moscow Region, Russia Department of Medical Nanobiotechnology, Pirogov Russian National Research Medical University, Moscow, Russia Laboratory of Biomedical Nanomaterials, NUST MISiS, Moscow Russia Mendeleev Chemical Technological University, Moscow, Russia 10.3762/bjnano.10.193 Abstract
  • . Unlike gadolinium agents, these agents have fewer contraindications for patients with renal failure and are less toxic [9]. However, despite the fact that the iron-containing agents have been approved for medical use, they are considered to have inferior characteristics as compared to positive contrast
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Published 02 Oct 2019

Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting

  • Xianping Liu,
  • Chengjuan Du,
  • Haichun Li,
  • Ting Jiang,
  • Zimiao Luo,
  • Zhiqing Pang,
  • Daoying Geng and
  • Jun Zhang

Beilstein J. Nanotechnol. 2019, 10, 1860–1872, doi:10.3762/bjnano.10.181

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  • spectrometry (ICP-MS, Thermo Scientific iCAP 7400 series) [39]. T2-weighted MR imaging of the PNPs with various Fe concentrations was performed under a 3.0T clinical MRI scanner (DiscoveryMR750, GE Medical System, LLC, USA) at room temperature [27]. Fluorescent images of the PNPs with various Fe concentrations
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Published 11 Sep 2019

Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione

  • Barbara Pem,
  • Igor M. Pongrac,
  • Lea Ulm,
  • Ivan Pavičić,
  • Valerije Vrček,
  • Darija Domazet Jurašin,
  • Marija Ljubojević,
  • Adela Krivohlavek and
  • Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175

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  • Barbara Pem Igor M. Pongrac Lea Ulm Ivan Pavicic Valerije Vrcek Darija Domazet Jurasin Marija Ljubojevic Adela Krivohlavek Ivana Vinkovic Vrcek Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10000 Zagreb, Croatia University of Zagreb, School of Medicine, Croatian
  • -chemical properties. Silver nanoparticles (AgNPs) are extensively used in antimicrobial coatings for medical devices, wound dressing, cosmetic products and food packaging due to their antimicrobial, antiangiogenic and anti-inflammatory properties [1][2][3][4][5]. Biomedical applications of gold
  • nanoparticles (AuNPs) range from molecular imaging, targeted drug delivery, gene therapy, cancer treatment or radio-sensitization and theranostics [1][4][6]. Moreover, AgNPs and AuNPs are among the most investigated engineered nanomaterials for medical use. A search performed in the Web of Science (WoS
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Published 02 Sep 2019

Growth dynamics and light scattering of gold nanoparticles in situ synthesized at high concentration in thin polymer films

  • Corentin Guyot,
  • Philippe Vandestrick,
  • Ingrid Marenne,
  • Olivier Deparis and
  • Michel Voué

Beilstein J. Nanotechnol. 2019, 10, 1768–1777, doi:10.3762/bjnano.10.172

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  • solar infrared radiation [3][4], in random lasers [5][6], in non-linear optical applications [7][8][9] and in sensors or bio-medical diagnostics [10][11][12]. More recently, nanocomposites containing AuNPs received even more attention due to their saturable absorption. Indeed, plasmonic nanocomposites
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Published 23 Aug 2019

Novel hollow titanium dioxide nanospheres with antimicrobial activity against resistant bacteria

  • Carol López de Dicastillo,
  • Cristian Patiño,
  • María José Galotto,
  • Yesseny Vásquez-Martínez,
  • Claudia Torrent,
  • Daniela Alburquenque,
  • Alejandro Pereira and
  • Juan Escrig

Beilstein J. Nanotechnol. 2019, 10, 1716–1725, doi:10.3762/bjnano.10.167

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  • (USACH), Obispo Umaña 050, 9170201 Santiago, Chile Center for the Development of Nanoscience and Nanotechnology (CEDENNA), 9170124 Santiago, Chile Program Center for Applied Biomedical Research, School of Medicine, Faculty of Medical Sciences, University of Santiago de Chile, 9170022 Santiago, Chile
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Published 19 Aug 2019

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

  • Hannah Onafuye,
  • Sebastian Pieper,
  • Dennis Mulac,
  • Jindrich Cinatl Jr.,
  • Mark N. Wass,
  • Klaus Langer and
  • Martin Michaelis

Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

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  • Münster, Corrensstr. 48, 48149 Münster, Germany Institute for Medical Virology, University Hospital, Goethe-University, Paul Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany 10.3762/bjnano.10.166 Abstract Resistance to systemic drug therapy is a major reason for the failure of anticancer therapies
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Published 14 Aug 2019

The effect of magneto-crystalline anisotropy on the properties of hard and soft magnetic ferrite nanoparticles

  • Hajar Jalili,
  • Bagher Aslibeiki,
  • Ali Ghotbi Varzaneh and
  • Volodymyr A. Chernenko

Beilstein J. Nanotechnol. 2019, 10, 1348–1359, doi:10.3762/bjnano.10.133

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  • magnetocrystalline anisotropy at room temperature [10]. The anisotropy constant of CoFe2O4 (K = 2 × 105 J·m−3) is nearly one order of magnitude larger than that of Fe3O4 [11][12][13]. Fe3O4 NPs have been studied extensively for bio-medical applications, such as drug delivery [14], magnetic resonance imaging (MRI
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Published 03 Jul 2019
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