Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

Optimizing PMMA solutions to suppress contamination in the transfer of CVD graphene for batch production

• Chun-Da Liao,
• Andrea Capasso,
• Tiago Queirós,
• Telma Domingues,
• Fatima Cerqueira,
• Nicoleta Nicoara,
• Jérôme Borme,
• Paulo Freitas and
• Pedro Alpuim

Beilstein J. Nanotechnol. 2022, 13, 796–806, doi:10.3762/bjnano.13.70

• a low-pressure CVD system (CVD First Nano, EasyTube 3000). A 25 µm thick annealed Cu foil (Alfa Aesar, purity 99.8%), serving as a metal catalyst, was placed in a graphite enclosed cavity during the whole process. The temperature for annealing and growth was kept stable at 1040 °C by PID thermal

Gelatin nanoparticles with tunable mechanical properties: effect of crosslinking time and loading

• Agnes-Valencia Weiss,
• Daniel Schorr,
• Julia K. Metz,
• Metin Yildirim,
• Saeed Ahmad Khan and
• Marc Schneider

Beilstein J. Nanotechnol. 2022, 13, 778–787, doi:10.3762/bjnano.13.68

• GmbH (Wetzlar, Germany). MLCT Cantilevers were purchased from Bruker France Nano Surfaces (Wissembourg, France). The human cell line A549 ACC107 [20] (DSMZ, Braunschweig, Germany) was cultivated in RPMI 1640 (Roswell Park Memorial Institute 1640, gibco™, Fisher Scientific, USA) supplemented with 10

• same day. AFM measurements were carried out with a JPK NanoWizard® 3 AFM (JPK Instruments, Berlin, Germany) using the MLCT cantilever tip D (Bruker France Nano Surfaces, Wissembourg, France) with a nominal resonance frequency of 15 kHz and a spring constant of 0.03 N/m. Before each measurement, the

• gelatin nanoparticles crosslinked for 0.5 h. Images were taken at 37 °C in Milli-Q® water running the JPK Nano Wizard 3 AFM executing the QI™-Mode. Young’s moduli of gelatin nanoparticles and crosslinking time. (A) Highlighting the linear dependency of crosslinking time and the resulting mechanical

Antibacterial activity of a berberine nanoformulation

• Hue Thi Nguyen,
• Tuyet Nhung Pham,
• Anh-Tuan Le,
• Nguyen Thanh Thuy,
• Tran Quang Huy and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2022, 13, 641–652, doi:10.3762/bjnano.13.56

• Hue Thi Nguyen Tuyet Nhung Pham Anh-Tuan Le Nguyen Thanh Thuy Tran Quang Huy Thuy Thi Thu Nguyen Phenikaa University Nano Institute (PHENA), Phenikaa University, Hanoi 12116, Vietnam National Institute of Hygiene and Epidemiology, Hanoi, Vietnam 10.3762/bjnano.13.56 Abstract This study describes

• transmission electron microscopy (TEM, JEM1010, JEOL). The dynamic average size distribution and the stability of the prepared BBR NPs in aqueous solution were evaluated by dynamic light scattering (DLS) using a Zetasizer Nano ZS, Malvern Instruments. Antibacterial activity of BBR NPs The antibacterial

Fabrication and testing of polymer microneedles for transdermal drug delivery

• Vahid Ebrahiminejad,
• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2022, 13, 629–640, doi:10.3762/bjnano.13.55

• . Acknowledgements This work was performed in part at the Queensland node of the Australian National Fabrication Facility, a company established under the National Collaborative Research Infrastructure Strategy to provide nano and microfabrication facilities for Australia’s researchers. This research was undertaken

Revealing local structural properties of an atomically thin MoSe₂ surface using optical microscopy

• Lin Pan,
• Peng Miao,
• Anke Horneber,
• Alfred J. Meixner,
• Pierre-Michel Adam and
• Dai Zhang

Beilstein J. Nanotechnol. 2022, 13, 572–581, doi:10.3762/bjnano.13.49

• measurements are performed using a custom-built confocal microscope assisted with a parabolic mirror, as shown in Supporting Information File 1, Figure S4. In this microscope, either a 636 nm diode laser (PDL 800-D, Picoquant) or a 532 nm laser (NANO 250-532 max, QIOPTIQ) in continuous wave mode are coupled to

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• Fluorescence spectrophotometer (Hitachi, Japan). Mean particle size and the zeta potential were recorded using a Zetasizer Nano ZS90 (Malvern, UK). A Nicolet iS10 infrared spectrometer (Nicolet, USA) was used to gather FTIR spectra in a scanning range of 400–4000 cm−1. Fluorescence images of cells were

Stimuli-responsive polypeptide nanogels for trypsin inhibition

• Petr Šálek,
• Jana Dvořáková,
• Sviatoslav Hladysh,
• Diana Oleshchuk,
• Ewa Pavlova,
• Jan Kučka and
• Vladimír Proks

Beilstein J. Nanotechnol. 2022, 13, 538–548, doi:10.3762/bjnano.13.45

• mg/mL) at 25 and 37 °C using a Zetasizer Nano ZS (Malvern Instruments Ltd., Worcestershire, UK) at 633 nm and 173° detection angle. Size and size distribution were obtained from the correlation function using CONTIN analysis available in the Malvern software. The hydrodynamic diameters (DH) were

Ethosomal (−)-epigallocatechin-3-gallate as a novel approach to enhance antioxidant, anti-collagenase and anti-elastase effects

• Çiğdem Yücel,
• Gökçe Şeker Karatoprak,
• Sena Yalçıntaş and
• Tuğba Eren Böncü

Beilstein J. Nanotechnol. 2022, 13, 491–502, doi:10.3762/bjnano.13.41

• of 1:1 (v/v). Characterization of formulations In the characterization studies, PS, ZP, and PDI of the developed ETHs were measured using a Zetasizer Nano ZS-Malvern. The ETHs were visualized using SEM. The content of EGCG entrapped in ETHs (EE%) was estimated after removal of the uncaptured drug

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

Effect of sample treatment on the elastic modulus of locust cuticle obtained by nanoindentation

• Chuchu Li,
• Stanislav N. Gorb and
• Hamed Rajabi

Beilstein J. Nanotechnol. 2022, 13, 404–410, doi:10.3762/bjnano.13.33

• ). The specimens were indented using a SA2 Nanoindenter (MTS Nano Instruments, Oak Ridge, TN, USA) equipped with a Berkovich diamond tip. The elastic modulus of the specimens was measured using the continuous stiffness measurement (CSM) technique. CSM is a well-established technique for obtaining the

• be used as a template for future studies that aim to measure cuticle properties using nanoindentation or other nano- or micromechanical testing methods. Data Accessibility All supporting data are made available in the article. Authors’ Contributions Conceptualization: SNG and HR; formal analysis: CL

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

• different characteristics and kinds of behavior of compounds on submicrometer and nanometer scales and resulted in the development of new methods such as electrospinning, self-assembly, phase separation, nano-imprinting, and photolithography for the generation of new biomaterials with improved properties

Systematic studies into uniform synthetic protein nanoparticles

• Nahal Habibi,
• Ava Mauser,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22

• thorough shape analysis into the assessment of emerging platforms from the very onset of their expansion into the general nano-bio research. The solution-based corollary to dry-state imaging that can provide the above parameters is dynamic light scattering (DLS). DLS uses the deconvolution of a correlation

• process. Dynamic light scattering DLS measurements were performed on particles in their hydrated state using a Zetasizer Nano ZS (Malvern Panalytical). The solution in which the particles were suspended was DPBS. DLS was employed to measure the particle size distribution after particle collection and

Photothermal ablation of murine melanomas by Fe₃O₄ nanoparticle clusters

• Xue Wang,
• Lili Xuan and
• Ying Pan

Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20

• quadratic fit of the correlation function. The particle size distribution was measured using the inbuilt DTS (nano) software. Samples were equilibrated for 1 min before measurement. All measurements were performed in triplicates. Hyperthermia effect of Fe3O4 nanoparticle clusters in solution The Fe3O4

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• , proliferation, and differentiation of the osteoblasts. However, the low fracture toughness and brittleness of akermanite have limited its use in load-bearing sites of bone tissue. To strengthen the mechanical properties nanoscale titania (nano-TiO2) was distributed into the ceramic matrix. A remarkable

• improvement in the mechanical properties was observed after the incorporation of 5 wt of nano-TiO2 and a bone-like apatite structure was formed in simulated body fluid (SBF), which supported cell attachment and growth, showing the potential for bone TE applications [73]. Human gingival fibroblasts (HGFs) are

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• mixture of PVA, sodium alginate, and PEO with incorporated nano-sized ZSM5 zeolite, which contains hydroxy functional groups (HZSM5). The maximum adsorption values of Th4+ and U6+ ions were found to be 274.6 and 144.7 mg/g, respectively, at a HZSM5 content of 10 wt %, an adsorbent dosage of 1 g/L, and pH

• flexible nanohybrid membrane of Pd NP-decorated polydopamine-SiO2/PVA, which can simultaneously remove organic dyes, chemicals, and oils [83]. (Figure 4 and Figure 5) Superhydrophilicity was found to be a synergistic effect of numerous hydroxy groups from SiO2 NPs and the nano/microscale surface roughness

A photonic crystal material for the online detection of nonpolar hydrocarbon vapors

• Evgenii S. Bolshakov,
• Aleksander V. Ivanov,
• Andrei A. Kozlov,
• Anton S. Aksenov,
• Elena V. Isanbaeva,
• Sergei E. Kushnir,
• Aleksei D. Yapryntsev,
• Aleksander E. Baranchikov and
• Yury A. Zolotov

Beilstein J. Nanotechnol. 2022, 13, 127–136, doi:10.3762/bjnano.13.9

• , Belgium/US). Instruments The average hydrodynamic radius of the PS particles has been determined by using the DLS method on a “Zetasizer Nano ZS” (Malvern Panalytical Ltd, UK) device. Microstructures of sensor matrices have been tested by using the SEM method on an “NVision 40” (Carl Zeiss, Inc., Germany

Bacterial safety study of the production process of hemoglobin-based oxygen carriers

• Axel Steffen,
• Yu Xiong,
• Radostina Georgieva,
• Ulrich Kalus and
• Hans Bäumler

Beilstein J. Nanotechnol. 2022, 13, 114–126, doi:10.3762/bjnano.13.8

• analysis, one drop of the sample was applied to a glass slide, dried overnight, and sputtered with gold. A Gemini Leo 1550 (Carl Zeiss AG, Oberkochen, Germany) instrument was utilized for the measurements at an operation voltage of 10 kV. The particle size was measured by DLS applying a Zetasizer Nano ZS

• utilizing an excitation wavelength of 488 nm and a 505 nm long-pass emission filter. The zeta potential of HbMP in 0.9% NaCl (pH 7.4, conductivity 17.2 ± 0.9 mS/cm) was measured using the Zetasizer Nano ZS instrument. For the determination of the concentration of free hemoglobin in the HbMP suspension

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles

• Sadaf Mushtaq,
• Khuram Shahzad,
• Tariq Saeed,
• Anwar Ul-Hamid,
• Bilal Haider Abbasi,
• Nafees Ahmad,
• Waqas Khalid,
• Muhammad Atif,
• Zulqurnain Ali and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99

• transmission electron microscopy (JEM 2100F) and energy dispersive spectroscopy (TESCAN-VEGA3), respectively. The magnetic behavior was determined by using a physical property measurement system (Quantum Design, USA). The colloidal stability and hydrodynamic size of NPs were studied by using a Zetasizer Nano

Identifying diverse metal oxide nanomaterials with lethal effects on embryonic zebrafish using machine learning

• Richard Liam Marchese Robinson,
• Haralambos Sarimveis,
• Philip Doganis,
• Xiaodong Jia,
• Marianna Kotzabasaki,
• Christiana Gousiadou,
• Stacey Lynn Harper and
• Terry Wilkins

Beilstein J. Nanotechnol. 2021, 12, 1297–1325, doi:10.3762/bjnano.12.97

• -fertilisation data were found to be harder to predict, which could reflect different exposure routes. Hence, subsequent analysis focused on the prediction of excess lethality at 120 hours-post fertilisation. The use of two data augmentation approaches, applied for the first time in nano-QSAR research, was

• these modelling results are on truly external data, which were not used to select the single descriptor model. This will require further laboratory work to generate comparable data to those studied herein. Keywords: data augmentation; embryonic zebrafish; machine learning; nanosafety; nano-QSAR

• last decade has seen a significant number of published studies present quantitative structure–activity relationships (QSARs) for predicting the biological effects of ENMs, commonly known as nano-QSARs, based upon calculated and/or measured variables (descriptors) related to their intrinsic or extrinsic

Nonmonotonous temperature dependence of Shapiro steps in YBCO grain boundary junctions

• Leonid S. Revin,
• Dmitriy V. Masterov,
• Alexey E. Parafin,
• Sergey A. Pavlov and
• Andrey L. Pankratov

Beilstein J. Nanotechnol. 2021, 12, 1279–1285, doi:10.3762/bjnano.12.95

• temperatures down to sub-kelvin, such as the phase diffusion regime [1][2][3], evidence for a minigap [4], and low-noise nano-junctions [5]. Such abilities raise not only fundamental interest in HTSC JJs but also an active search for ways to practically use such JJs. In recent years, the limiting

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

• themselves at various length scales. Interestingly, fractals can also be fabricated artificially in labs under controlled growth environments and be explored for various applications. Such fractals have a repeating unit that spans in length from nano- to millimeter range. Fractals thus can be regarded as

• connectors that structurally bridge the gap between the nano- and the macroscopic worlds and have a hybrid structure of pores and repeating units. This article presents a comprehensive review on inorganic fabricated fractals (fab-fracs) synthesized in labs and employed as gas sensors across materials

• ) [10][11][12][13][14][15][16], nanorods [17][18][19][20], nanosheets [21][22][23], nanobelts [24][25], and nano/micro-spheres/cubes/polyhedrons [26][27][28][29] with enhanced sensitivity as a gas sensor. A rich collection of research articles and review papers on distinct morphological nanostructured

Irradiation-driven molecular dynamics simulation of the FEBID process for Pt(PF₃)₄

• Alexey Prosvetov,
• Alexey V. Verkhovtsev,
• Gennady Sushko and
• Andrey V. Solov’yov

Beilstein J. Nanotechnol. 2021, 12, 1151–1172, doi:10.3762/bjnano.12.86

• and dynamics of complex “meso-bio-nano” systems [14]. MBN Studio is a powerful multi-task toolkit enabling to set up and start MBN Explorer calculations, to monitor their progress, to examine calculation results, to visualize inputs and outputs, and to analyze specific characteristics determined by

Open-loop amplitude-modulation Kelvin probe force microscopy operated in single-pass PeakForce tapping mode

• Gheorghe Stan and
• Pradeep Namboodiri

Beilstein J. Nanotechnol. 2021, 12, 1115–1126, doi:10.3762/bjnano.12.83

• substrate (Bruker Nano Surfaces, Santa Barbara, CA, USA); the metal regions are separated by trenches that expose the Si substrate at their bottom. Figure 1a shows the AFM topographical image of one of these trenches, bordered by Au (left) and Al (right). The CPD maps over the sample were obtained first by