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Search for "PMO" in Full Text gives 2 result(s) in Beilstein Journal of Nanotechnology.

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

  • Ana Cubillo Alvarez,
  • Dylan Maguire and
  • Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

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  • oligomer (PMO); phosphorothioate (PS); polyplexes; ribose substitutions; small interfering RNA (siRNA); synthetic polymers; tricyclo-DNA (tcDNA); Introduction The development and use of personalised therapies tailored to individual patients have emerged as a powerful strategy for treating various
  • of cysteine-PNAs via disulfide linkage [126]. These compounds showed a PNA dose-dependent cell toxicity and exhibited up to almost 20-fold increased luciferase activity compared to free arginine-PNAs and dithiothreitol control. In another study, Kuhn et al. developed aminoethylene-based PMO
  • PMO conjugate containing linolenic acid with three double bonds (LenA) exhibited enhanced cellular internalisation while maintaining high cell viability on various cell lines, leading to the highest splice switching activity (Figure 8). Poly(propylene imine). Since pioneering research by Vögtle and
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Published 27 Mar 2025

Distribution of functional groups in periodic mesoporous organosilica materials studied by small-angle neutron scattering with in situ adsorption of nitrogen

  • Monir Sharifi,
  • Dirk Wallacher and
  • Michael Wark

Beilstein J. Nanotechnol. 2012, 3, 428–437, doi:10.3762/bjnano.3.49

Graphical Abstract
  • in the benzene-PMO, due to the fact that the benzene-PMO walls possess a neutron scattering length density (SLD) similar to that of nitrogen in the condensed state. However, signals at higher q-values (>1 1/Å) are not affected with respect to their SANS intensity, even after complete pore filling
  • , confirming the assumption of a crystal-like periodicity within the PMO material walls due to π–π interactions between the organic bridges. The SLD of pristine benzene-PMO was altered by functionalizing the surface with different amounts of SO3H-groups, using the grafting method. For a low degree of
  • diffraction signals is no longer observed proving that homogeneously distributed SO3H-groups on the inner pore walls of the benzene-PMO alter the SLD in a way that it no longer fits to the SLD of the condensed N2. Keywords: contrast matching; crystal-like periodicity; distribution of functional groups; PMO
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Published 30 May 2012
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