Fabrication and evaluation of BerNPs regarding the growth and development of Streptococcus mutans

• Tuyen Huu Nguyen,
• Hong Thanh Pham,
• Kieu Kim Thanh Nguyen,
• Loan Hong Ngo,
• Anh Ngoc Tuan Mai,
• Thu Hoang Anh Lam,
• Ngan Thi Kim Phan,
• Dung Tien Pham,
• Duong Thuy Hoang,
• Thuc Dong Nguyen and
• Lien Thi Xuan Truong

Beilstein J. Nanotechnol. 2025, 16, 308–315, doi:10.3762/bjnano.16.23

• Faculty of Medical Technology, Van Lang University, Ho Chi Minh City, Vietnam Department of Biotechnology, Nong Lam University, Ho Chi Minh City, Vietnam Faculty of Pharmacy, Van Lang University, Ho Chi Minh City, Vietnam 10.3762/bjnano.16.23 Abstract In this study, berberine nanoparticles (BerNPs) were

• formation of S. mutans. In summary, BerNPs demonstrated a potent inhibitory effect on the activities of S. mutans at selectively applied concentrations. Keywords: antibacterial; berberine nanoparticles; BerNPs; biofilm; FE-SEM; Streptococcus mutans; Introduction According to the Global Burden of Disease

• inhibitory activity against pathogenic bacteria have been reported. In 2022, Nguyen et al. fabricated berberine nanoparticles (BerNPs) by antisolvent precipitation (ASP) using glycerol as a safe organic solvent and evaluated their antibacterial activity on S. aureus and E. coli O157:H7 [12]. Additionally

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• Berberine nanoparticles were formed through the antisolvent precipitation process described in our previous report [7]. A 7.0 wt % PLA solution was prepared by dissolving the PLA pellets in a solvent mixture of DCM/DMF with a weight ratio of 80/20 under magnetic stirring for 1 h at 50 °C. After that, the

Antibacterial activity of a berberine nanoformulation

• Hue Thi Nguyen,
• Tuyet Nhung Pham,
• Anh-Tuan Le,
• Nguyen Thanh Thuy,
• Tran Quang Huy and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2022, 13, 641–652, doi:10.3762/bjnano.13.56

• bacterial cells and severely damaged the cell walls. Therefore, BBR NPs prepared by ASP appear to be a potential candidate for the treatment of bacterial pathogens. Keywords: antibacterial activity; antisolvent precipitation (ASP); berberine nanoparticles (BBR NPs); glycerol; solubility; Introduction