Fabrication and evaluation of BerNPs regarding the growth and development of Streptococcus mutans

• Tuyen Huu Nguyen,
• Hong Thanh Pham,
• Kieu Kim Thanh Nguyen,
• Loan Hong Ngo,
• Anh Ngoc Tuan Mai,
• Thu Hoang Anh Lam,
• Ngan Thi Kim Phan,
• Dung Tien Pham,
• Duong Thuy Hoang,
• Thuc Dong Nguyen and
• Lien Thi Xuan Truong

Beilstein J. Nanotechnol. 2025, 16, 308–315, doi:10.3762/bjnano.16.23

• substances, resulting in color fading and the emergence of graphene-based filaments. Du et al. showed that berberine affects Streptococcus pyogenes by regulating proteins in the KEGG pathway, leading to the accumulation of reactive oxygen species (ROS) hindering the biosynthesis of DNA, proteins, and lipids

• biosynthesis of S. mutans, has been reported to be inhibited by berberine [39]. The inhibition of biofilm formation by S. mutans was also observed in the study by Zhou and coworkers. The results showed that berberine chloride hydrate effectively downregulated the expression of the genes srtA, spaP, gbpC, comX

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• biosynthesis of ZnO NPs. The formation of a white precipitate at the flask’s bottom served as an indicator of ZnO NP production. XRD analysis The XRD patterns revealed a strong agreement with the hexagonal wurtzite structure, which is characteristic of ZnO NPs. This assertion was substantiated by comparison

• wurtzite structure. Similarly, in another study, Suba et al. [22] also described the biosynthesis of hexagonal ZnO NPs using Lactiplantibacillus spp. Valuable insights into the synthesis process were obtained through FTIR spectroscopy. The peak at 484 cm−1 confirms the occurrence of Zn–O linkages

Green synthesis of silver nanoparticles derived from algae and their larvicidal properties to control Aedes aegypti

• Matheus Alves Siqueira de Assunção,
• Douglas Dourado,
• Daiane Rodrigues dos Santos,
• Gabriel Bezerra Faierstein,
• Mara Elga Medeiros Braga,
• Severino Alves Junior,
• Rosângela Maria Rodrigues Barbosa,
• Herminio José Cipriano de Sousa and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 1566–1575, doi:10.3762/bjnano.15.123

• cost and sustainable biosynthesis. In the perspective of using AgNPs in the development of novel insecticides for vector control, this review deals with the eco-friendly synthesis of AgNPs through seaweed extracts as reducing and stabilizing agents. In addition, assessment of toxicity of these

• evaluated as potential reducing agents in the biosynthesis of AgNPs were the secondary amines, aromatic primary amines, carboxylates, amides, alkenes, and aromatic compounds. Roni and collaborators prepared AgNPs from red algae [52]. An aqueous extract of H. musciformis was obtained (10 g of seaweed leaves

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans

• Romana Petry,
• James M. de Almeida,
• Francine Côa,
• Felipe Crasto de Lima,
• Diego Stéfani T. Martinez and
• Adalberto Fazzio

Beilstein J. Nanotechnol. 2024, 15, 1297–1311, doi:10.3762/bjnano.15.105

• biosynthesis protein COQ7 [51][53][54][55]. The co-exposure of GO with antioxidant molecules, such as ʟ-cysteine and ascorbate, can mitigate the oxidative effects of the material and minimize GO’s toxicity [35][53]. Moreover, GO also shows important neuronal effects; for example, it influences protein–protein

Assessing phytotoxicity and tolerance levels of ZnO nanoparticles on Raphanus sativus: implications for widespread adoptions

• Pathirannahalage Sahan Samuditha,
• Nadeesh Madusanka Adassooriya and
• Nazeera Salim

Beilstein J. Nanotechnol. 2024, 15, 115–125, doi:10.3762/bjnano.15.11

• content in olive tree (cv. Moraiolo) shoots in vitro was reported upon treatment with ZnO NPs at concentrations of 6 and 18 mg/L [35]. Zinc is essential for the synthesis of tryptophan, an amino acid required for the biosynthesis of IAA. Zinc has an indirect influence on auxins by activating tryptophan

• synthase, an enzyme responsible for the synthesis of tryptophan in the biosynthesis of IAA [36][37]. According to the present results, ZnO NPs have no toxic effect on IAA content at 1000 mg/L; however, it increased the IAA content at 2000 mg/L. Zinc oxide NPs are a potential candidate to enhance the

New trends in nanobiotechnology

• Pau-Loke Show,
• Kit Wayne Chew,
• Wee-Jun Ong,
• Sunita Varjani and
• Joon Ching Juan

Beilstein J. Nanotechnol. 2023, 14, 377–379, doi:10.3762/bjnano.14.32

• . Green synthesis methods were firstly applied for the biosynthesis of silver nanoparticles, along with silver chloride nanoparticles as there were chlorine salts in the pineapple peels which enable the formation of silver chloride. These nanoparticles were then characterized and tested regarding their

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• , Saltillo Coahuila, 25294, México 10.3762/bjnano.13.124 Abstract Green synthesis may be a useful approach to achieve selective cytotoxicity of silver nanoparticles on cancer cells and healthy cells. In this study, the concomitant biosynthesis of silver (Ag)/silver chloride (AgCl) nanoparticles from

• a dose-dependent manner. Based on the aforementioned findings, and considering the high content of phenolic compounds in the pineapple peel, which function as reducing agents of silver salt, the present study shows biosynthesis of Ag/AgCl nanoparticles using a pineapple peel extract. The study was

• conducted by monitoring biosynthesis temperature, considering that this variable has an important influence on the formation of nanoparticles. To verify the biological behavior of the obtained Ag/AgCl nanoparticles, their cytotoxic activity in the MCF-7 breast cancer cell line was investigated. The novelty

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

• . These chemical methods can be divided into two major techniques, namely chemical vapor deposition (CVD) with liquid-phase synthesis and colloidal synthesis. In general, the colloidal synthesis of NPs is highly acclaimed due to its versatility [16]. So-called bio-assisted methods, biosynthesis, or green

Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles

• Sadaf Mushtaq,
• Khuram Shahzad,
• Tariq Saeed,
• Anwar Ul-Hamid,
• Bilal Haider Abbasi,
• Nafees Ahmad,
• Waqas Khalid,
• Muhammad Atif,
• Zulqurnain Ali and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99

• , however, leads to apoptosis [58]. Conversely, Ki-67 is an important proliferative and prognostic cancer biomarker expressed in the nucleus during the cell cycle. It is important for cell division and biosynthesis of ribosomal RNA and it is variably expressed throughout the cell cycle (high in the G2/M

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

The preparation temperature influences the physicochemical nature and activity of nanoceria

• Robert A. Yokel,
• Wendel Wohlleben,
• Johannes Georg Keller,
• Matthew L. Hancock,
• Jason M. Unrine,
• D. Allan Butterfield and
• Eric A. Grulke

Beilstein J. Nanotechnol. 2021, 12, 525–540, doi:10.3762/bjnano.12.43

• as the beneficial biological effects and human diseases that could potentially be treated [11], and the physicochemical properties that mediate the effects of nanoceria, its biochemical properties, biosynthesis, and its major biomedical applications, including biosensors [12]. Additional applications

The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors

• Nikola Geskovski,
• Nadica Matevska-Geshkovska,
• Simona Dimchevska Sazdovska,
• Marija Glavas Dodov,
• Kristina Mladenovska and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31

• energy and material for membrane biosynthesis, and fat-soluble vitamins [25]. In the past, this pathway was generally ignored as a targeting possibility, mostly because the BM contribution to the RES is quite negligible compared to that of spleen and liver. Also, there was a lack of understanding and

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

• biosynthesis occurs outside of cells due to the presence of biomolecules [191], which depends on the type of cell culture used. For instance, cell-wall deficient cells are typically more inclined towards intracellular biosynthesis as the cell-wall is known to act as a barrier for the diffusion of metal cations

• reaction temperatures, use of non-hazardous reagents, and synthesis of relatively small particles with uniform morphology. However, the main disadvantage of this type of biosynthesis is the significantly low production rate [264][265]. 3.5 Plant/plant-extract-mediated synthesis The synthesis of Ag

Selective detection of complex gas mixtures using point contacts: concept, method and tools

• Alexander P. Pospelov,
• Victor I. Belan,
• Dmytro O. Harbuz,
• Volodymyr L. Vakula,
• Lyudmila V. Kamarchuk,
• Yuliya V. Volkova and
• Gennadii V. Kamarchuk

Beilstein J. Nanotechnol. 2020, 11, 1631–1643, doi:10.3762/bjnano.11.146

• ]. The main goal of these studies is to find peculiarities of the human metabolism that are typical of various diseases and to develop new noninvasive medical diagnostic methods. The functioning of the human body is accompanied by the biosynthesis of specific chemical substances. These substances become

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• synthesis" or "nanoparticle biosynthesis" methods, has arisen. In addition to their ecologically friendly nature, these techniques also present a higher performance, less energy costs (temperature and pressure), and they are profitable, biocompatible, safe, and easy to expand on a larger scale [72][74

Preparation and in vivo evaluation of glyco-gold nanoparticles carrying synthetic mycobacterial hexaarabinofuranoside

• Gennady L. Burygin,
• Polina I. Abronina,
• Nikita M. Podvalnyy,
• Sergey A. Staroverov,
• Leonid O. Kononov and
• Lev A. Dykman

Beilstein J. Nanotechnol. 2020, 11, 480–493, doi:10.3762/bjnano.11.39

• antiserum against LPS of Azospirillum brasilense Sp7, generated in the presence of CFA [99], with M. bovis, M. phlei, M. smegmatis and E. coli cell suspensions could be detected (Figure 6). Discussion The biosynthesis of antibodies in mammals is induced by immunogenic substances. These compounds are

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

• Jaison Jeevanandam,
• Ahmed Barhoum,
• Yen S. Chan,
• Alain Dufresne and
• Michael K. Danquah

Beilstein J. Nanotechnol. 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98

• . These are called as nanobacteria and are highly useful in the biosynthesis of low toxicity NPs [137]. Pseudomonas stutzeri A259 is the first bacteria to be used to produce Ag NPs [138]. Later, many metal NPs, such as gold [139][140], alloy NPs [141][142], nonmagnetic oxide NPs [143][144][145][146][147

Humidity-dependent wound sealing in succulent leaves of Delosperma cooperi – An adaptation to seasonal drought stress

• Olga Speck,
• Mark Schlechtendahl,
• Florian Borm,
• Tim Kampowski and
• Thomas Speck

Beilstein J. Nanotechnol. 2018, 9, 175–186, doi:10.3762/bjnano.9.20

• , reversible cross-linking) are involved, a transfer to technology is especially promising. However, if biological mechanisms such as metabolism-driven modifications (e.g., biosynthesis, cell proliferation) are present, the technical application is much more difficult. A clear distinction must also be made

• mechanically driven mechanism. Subsequent to the relatively fast initial self-sealing processes, self-healing including biosynthesis and cell proliferation starts, and hence the formation of a specific wound healing tissue. After a few weeks, self-healing is completed showing pronounced healed tissue in the

Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization

• Mohamed Hamed Misbah,
• Mercedes Santos,
• Luis Quintanilla,
• Christina Günter,
• Matilde Alonso,
• Andreas Taubert and
• José Carlos Rodríguez-Cabello

Beilstein J. Nanotechnol. 2017, 8, 772–783, doi:10.3762/bjnano.8.80

• biology experiments for gene construction were performed using standard methods. ELR production was carried out using cellular systems for genetically engineered protein biosynthesis in E. coli and purification was performed with several cycles of temperature-dependent reversible precipitation. After

Preparation of alginate–chitosan–cyclodextrin micro- and nanoparticles loaded with anti-tuberculosis compounds

• Albert Ivancic,
• Fliur Macaev,
• Fatma Aksakal,
• Veaceslav Boldescu,
• Serghei Pogrebnoi and
• Gheorghe Duca

Beilstein J. Nanotechnol. 2016, 7, 1208–1218, doi:10.3762/bjnano.7.112

• and candidosis (cutaneous and vaginal) [20]. The main mechanism of the fungistatic effect of ISN is the inhibition of lanosterol 14a-demethylation in the ergosterol biosynthesis in the fungal membrane. At the same time, in the case of a prolonged use of ISN, a fungicidal effect can be observed, which

• aminoglutethimide [27]. We have suggested that isoconazole is an active inhibitor of enoyl–acyl carrier protein reductase (InhA) from M. tuberculosis. InhA is one of the key enzymes involved in the fatty acid biosynthesis of the mycobacterium and is an effective antimicrobial target. InhA inhibitors are promising

Time-dependent growth of crystalline Au⁰-nanoparticles in cyanobacteria as self-reproducing bioreactors: 2. Anabaena cylindrica

• Liz M. Rösken,
• Felix Cappel,
• Susanne Körsten,
• Christian B. Fischer,
• Andreas Schönleber,
• Sander van Smaalen,
• Stefan Geimer,
• Christian Beresko,
• Georg Ankerhold and
• Stefan Wehner

Beilstein J. Nanotechnol. 2016, 7, 312–327, doi:10.3762/bjnano.7.30

• Bayreuth, Lehrstuhl für Kristallographie, 95440 Bayreuth, Germany Universität Bayreuth, Zellbiologie / Elektronenmikroskopie, 95440 Bayreuth, Germany Hochschule Koblenz, RheinAhrCampus Remagen, Optics and Laser Engineering, 53424 Remagen, Germany 10.3762/bjnano.7.30 Abstract Microbial biosynthesis of

• metal nanoparticles as needed in catalysis has shown its theoretical ability as an extremely environmentally friendly production method in the last few years, even though the separation of the nanoparticles is challenging. Biosynthesis, summing up biosorption and bioreduction of diluted metal ions to

• nanoparticles are found to be located along the thylakoid membranes. Keywords: biosynthesis; gold nanoparticles; laser-induced breakdown spectroscopy (LIBS); transmission electron microscopy (TEM); X-ray powder diffraction (XRD); Introduction Precious metallic nanoparticles are of steadily increasing interest

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• in vivo [70][71][72][73][74]. The biosynthesis of metallic NMs with controlled morphology is governed by using different bacterial strains [68]. For example, Pseudomonas stutzeri AG259, a metal-accumulating bacterium, is able to synthesize AgNPs through its detoxification process after exposure to

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

Green synthesis, characterization and catalytic activity of natural bentonite-supported copper nanoparticles for the solvent-free synthesis of 1-substituted 1H-1,2,3,4-tetrazoles and reduction of 4-nitrophenol

• Akbar Rostami-Vartooni,
• Mohammad Alizadeh and
• Mojtaba Bagherzadeh

Beilstein J. Nanotechnol. 2015, 6, 2300–2309, doi:10.3762/bjnano.6.236

• recent research on tetrazoles, 1-substituted 1H-1,2,3,4-tetrazoles was found to be a special category due to their biological activity [16]. The plant biosynthesis of nanoparticles immobilized on natural supports is a subject of new research as little has been published on this topic [17][18]. Therefore

• , the use of plants as a natural and biological source for biosynthesis of nanoparticles should be explored. Common thyme with the scientific name Thymus vulgaris is one of the plants indigenous to Iran which is valued for its antiseptic and antioxidant properties [19]. Thymol (1), carvacrol (2), p

Biocompatibility of cerium dioxide and silicon dioxide nanoparticles with endothelial cells

• Claudia Strobel,
• Martin Förster and
• Ingrid Hilger

Beilstein J. Nanotechnol. 2014, 5, 1795–1807, doi:10.3762/bjnano.5.190

• CeO2 nanoparticles (sample #A, 24 h of incubation, HUVEC). The findings demonstrate the complexity of reactions in terms of protein biosynthesis and protein release – even alterations of the cellular vesicular transport are conceivable. It cannot be excluded that cell material of dead cells could