Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

• Ömür Acet,
• Pavel Kirsanov,
• Burcu Önal Acet,
• Inessa Halets-Bui,
• Dzmitry Shcharbin,
• Şeyda Ceylan Cömert and
• Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

• that observed for the commercial liposomal formulation of doxorubicin Doxil. The obtained results demonstrated that smart nanopolymers can be efficiently used to create new types of doxorubicin-based drugs. Keywords: cancer cell line HeLa; cytotoxicity; doxorubicin; drug delivery; smart nanopolymers

• characterize the SNPs. In addition to experiments regarding the DOX loading capacity of the SNPs at different concentrations, the effect of pH and temperature on the release of DOX was also investigated. Finally, the cytotoxicity of DOX-SNPs against the cancer cell line HeLa at different concentrations and

• saline (PBS), pH 7.4. The effect on the cancer cell line HeLa was studied after incubation for 24, 48, 72, and 96 h at 37 °C. After incubation, the medium was discarded from the wells, and 50 µL of MTT (0.5 mg/mL in 0.05 mol/L PBS, pH 7.4) were added to each well. The incubation time with MTT is 4 h

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• cancer cells, which may be attributed to the expression of cross antigens on different cells. Pan et al. found that breast cancer MDA-MB-231 membrane-coated NPs also showed a certain affinity for the cervical cancer cell line HeLa [39]. 2.2 Modulation of the immune system Cancer cells exhibit excellent

Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells

• Nils Bohmer and
• Andreas Jordan

Beilstein J. Nanotechnol. 2015, 6, 167–176, doi:10.3762/bjnano.6.16

• the internalization behavior of HeLa cells in vitro. Discussion The aim of the study was to elucidate, how human cancer cells internalize iron oxide nanoparticles with silica shells, which have no target function for a special application or receptor. Therefore the human cervical cancer cell line HeLa