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Search for "hemocompatibility" in Full Text gives 8 result(s) in Beilstein Journal of Nanotechnology.
A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery
Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2
- ). Cytotoxicity and hemocompatibility According to the cytotoxicity investigation, p(Hist-CA), Hist-RA, and CA-RA were all found to be lowly toxic. Hist-RA showed IC50 values greater than 0.22 mM for the WI38 human embryonic lung cell line and the Chang liver human liver cell line (Table 2). The IC50 values for
- antidote delivery. Under healthy conditions, with a neutral pH and normal glucose concentrations, the nanocarrier is found to be stable. The employed resorcinarenes and the nanocarrier exhibit good hemocompatibility and low cytotoxicity with respect to human embryonic lung cells (WI38) and a healthy liver
Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects
Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118
- showed excellent pharmaceutical attributes with small particle size (PS), high zeta potential (ZP), and high entrapment efficiency (EE). The CUR-PLHNPs were tested for hemocompatibility in the drug concentration range of 60–12000 μg/mL, and the results indicated that the CUR-PLHNPs were non-hemolytic
A biomimetic approach towards a universal slippery liquid infused surface coating
Beilstein J. Nanotechnol. 2024, 15, 1376–1389, doi:10.3762/bjnano.15.111
- spectroscopy. Finally, ordering of specific chemical groups within our PDA SLIPS layer was determined via sum frequency generation spectroscopy. The hemocompatibility of our new PDA-based SLIPS coating was then evaluated by tracking FXII activation, fibrin generation time, clot morphology, and platelet
- adhesion to the surface. This hemocompatibility work suggests that PDA SLIPS coatings slow or prevent clotting, but the observation of both FXII activation and the presence of adherent and activated platelets at the PDA SLIPS samples imply that this formulation of a SLIPS coating is not completely
- omniphobic. Keywords: biocompatibility; biomimetic; blood-contacting; hemocompatibility; non-fouling; Introduction Clot formation and the overall compatibility of artificial materials within the body remains a common complication of blood contacting surfaces [1][2][3][4][5][6][7][8]. A critical hurdle in
Bacterial safety study of the production process of hemoglobin-based oxygen carriers
Beilstein J. Nanotechnol. 2022, 13, 114–126, doi:10.3762/bjnano.13.8
- modifications [5][6]. Thus, it was possible to immobilize vitamin B2 (riboflavin) in these particles together with human serum albumin (HSA). This resulted in a drug delivery system with good hemocompatibility and release of riboflavin over a prolonged period [7]. In addition, HSA microparticles could be loaded
Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles
Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99
- penetration and hemocompatibility which can be useful for biomedical applications [12][17]. Furthermore, in order to be exploited in biomedical applications, NPs need to fulfill certain criteria which include water solubility, excellent colloidal stability, biocompatibility, and high saturation magnetization
Use of nanosystems to improve the anticancer effects of curcumin
Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78
- inhibition without any obvious side effects. Kumar et al. [86] reported CUR-loaded polymer/lipid-based nanoparticles made with the emulsification–evaporation method. They report 53% EE, hemocompatibility in the range of 60–120 µg/mL, and improved apoptotic activity in MCF-7 cells as compared to free CUR [86
Identification of physicochemical properties that modulate nanoparticle aggregation in blood
Beilstein J. Nanotechnol. 2020, 11, 550–567, doi:10.3762/bjnano.11.44
- aim of reducing costs, which can also accelerate the translation into the market. In the case of materials, the application these approaches is hampered by poor knowledge of how the physical and chemical properties of the material trigger the biological response. Hemocompatibility is a crucial aspect
The surface microstructure of cusps and leaflets in rabbit and mouse heart valves
Beilstein J. Nanotechnol. 2014, 5, 622–629, doi:10.3762/bjnano.5.73
- smooth to the naked eye, they are actually comprised of a double hierarchical structure consisting of a cobblestone-like microstructure and nano-cilia along with mastoids with a directional arrangement. Such nanostructures could play a very important role in the hemocompatibility characteristics of heart
- fabrication of valve substitutes or partial substitutes. Namely, the model may help ameliorate heart valve replacement surgery. Keywords: contact angle; geometric parameter; heart valve; hemocompatibility; microstructure; Introduction Bionics, or biomimetics, have made tremendous developments in the past
- /leaflets taken from animals are studied along with the effect of these microstructures on blood flow characteristics. Thus, this study will help improve the hemocompatibility of artificial heart valves. Experimental Sample preparation: The thoracic cavities of the rabbits and the mice were cut open by
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