Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

• Selin Akpinar Adscheid,
• Akif E. Türeli,
• Nazende Günday-Türeli and
• Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

• ; intranasal delivery; liposomes; nanomedicine; nanostructured lipid carriers (NLCs); polymer nanoparticles; RNA delivery; solid lipid nanoparticles (SLNs); Introduction The central nervous system (CNS) consists of the brain and the spinal cord and is considered the body’s processing and control center. While

• the low drug loading capacity and drug expulsion during storage because of an increased crystallization tendency [102]. Researchers developed a second generation of lipid-based drug carriers called nanostructured lipid carriers (NLCs). Unlike the SLNs, the core structure of the NLCs is composed of

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• following the Ambisome® path. Nanostructured lipid carriers Nanostructured lipid carriers (NLCs) are lipid-based formulations with a solid matrix at room temperature that differ from solid lipid nanoparticles when it comes to their matrix organizational level. Nanostructured lipid carriers offer advantages

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

Key for crossing the BBB with nanoparticles: the rational design

• Sonia M. Lombardo,
• Marc Schneider,
• Akif E. Türeli and
• Nazende Günday Türeli

Beilstein J. Nanotechnol. 2020, 11, 866–883, doi:10.3762/bjnano.11.72

• applications of nanostructured lipid carriers (NLCs) for brain delivery are using the intranasal pathway [164][165][166][167], some studies have shown that NLC are also able to deliver drugs to the brain through the BBB. NLC are lipid-based particles composed of a liquid lipid phase inside a solid lipid phase

BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products

• Florence Olechowski,
• Rainer H. Müller and
• Sung Min Pyo

Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208

• inclusion; nanostructured lipid carriers (NLCs); penetration enhancement; skin occlusion; SmartLipids; solid lipid nanoparticles (SLNs); Introduction To meet the increasing expectations and demands of consumers in personal care and cosmetics, as well of patients in medical care, dermal delivery systems are

• and therefore are solid at body temperature. The second generation of these particles, the nanostructured lipid carriers (NLCs), made it to the cosmetic market in 2005 and are typically a mixture of one solid lipid and one liquid lipid [4], e.g., tristearin and caprylic/capric triglyceride, also being

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

• Elisabetta Esposito,
• Maddalena Sguizzato,
• Markus Drechsler,
• Paolo Mariani,
• Federica Carducci,
• Claudio Nastruzzi,
• Giuseppe Valacchi and
• Rita Cortesi

Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

• (SLNs) and nanostructured lipid carriers (NLCs) [26][27][28]. SLNs possess several advantages over conventional lipid formulations being able to carry drugs in a biocompatible solid nanometric matrix, thus achieving improvement of solubility, stability of the loaded active molecule and suitability of

• -actin. The results are shown as the mean of three experiments. * p < 0.05 with respect to the control. Composition of solid lipid nanoparticles (SLNs). Composition of nanostructured lipid carriers (NLCs). Composition of antioxidant-containing NLCs. Dimensional characteristics of SLNs or NLCs and the

• lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs); Introduction Air pollution increasingly affects industrialized urban areas in a negative manner with dramatic consequences for the environment and human health. This problem also affects rural areas, worsening the