Attempts to preserve and visualize protein corona on the surface of biological nanoparticles in blood serum using photomodification

• Julia E. Poletaeva,
• Anastasiya V. Tupitsyna,
• Alina E. Grigor’eva,
• Ilya S. Dovydenko and
• Elena I. Ryabchikova

Beilstein J. Nanotechnol. 2024, 15, 1654–1666, doi:10.3762/bjnano.15.130

• protein corona is present on any nanoparticle (NP) entering biological fluids; however, the existence of a natural protein corona on natural NPs has not been experimentally confirmed. We used our previously developed photomodification method to fix the natural corona on “biological nanoparticles” (bio-NPs

• obtained direct images of a “natural” protein corona on natural bio-NPs of blood serum for the first time Keywords: chylomicrons; extracellular vesicles; lipoproteins; photomodification; protein corona; Introduction The existence of a protein corona on all nanoparticles (NPs) entering biological fluids

• prevent the corona loss, we fixed it on the surface of the bio-NPs by the photomodification method. We developed this method recently for fixing a full protein corona on model NPs with lipid envelope. One of the proofs of protein corona formation on the particle surface was its visualization using TEM [23

Electro-optical interfacial effects on a graphene/π-conjugated organic semiconductor hybrid system

• Karolline A. S. Araujo,
• Luiz A. Cury,
• Matheus J. S. Matos,
• Thales F. D. Fernandes,
• Luiz G. Cançado and
• Bernardo R. A. Neves

Beilstein J. Nanotechnol. 2018, 9, 963–974, doi:10.3762/bjnano.9.90

• , photomodification of graphene-RA interfacial dipole, surface band bending and others [39][40][41][42][43][44][45]. An analysis of the exact contribution of each mechanism might be very complex and is out of the scope of the present work. The realization of RA SAMs atop other 2D materials and its subsequent