Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• the photothermal properties of these nanomaterials and their innovative therapeutic mechanisms. We review the latest research on photothermal nanomaterial-based treatments for various eye diseases. Additionally, we discuss the current challenges and future perspectives in this field, with a focus on

• nanomaterials for treating various ophthalmic diseases, including ocular tumors, glaucoma, cataracts, vitreous opacity, endophthalmitis, and decreased visual acuity. It also summarizes the structure–activity relationships between the photothermal properties of these materials and novel therapeutic mechanisms

• , and inorganic semiconductor materials that absorb light through bandgap transitions [25]. The specific photothermal properties of these materials, encompassing aspects such as range and rate of light absorption, photothermal conversion efficiency, heat transfer capability, and photothermal stability

Gold nanomakura: nanoarchitectonics and their photothermal response in association with carrageenan hydrogels

• Nabojit Das,
• Vikas,
• Akash Kumar,
• Sanjeev Soni and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 678–693, doi:10.3762/bjnano.15.56

• hydrogels for enabling usage on nanophotonic, photothermal, and bio-imaging applications. Keywords: anisotropy; hydrogel; kappa-carrageenan; metal nanoparticles; nanoarchitectonics; nanomakura; photothermal properties; surfactants; Introduction Nanoarchitectonics is the fabrication of functional material

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

• Zeynep Özcan and
• Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

• temperature induced by the thermosensitive Fe3O4 NPs. Furthermore, the enhanced heating due to the photothermal properties of PDA facilitated the separation of VNB from the structure [45]. As shown in Figure 5c, it is worth noting that the temperature of PDA/Fe3O4 NPs increased from 25 to 45 °C in 3 min

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• analytes using LFAs. One of the promising strategies is to enhance the photothermal properties of nanomaterials to generate heat after light irradiation, followed by a temperature measurement to detect and quantify the analyte concentration. Recently, it has been observed that the nanoscale architecture of

• materials, including size, shape, and nanoscale composition, plays a significant role in enhancing the photothermal properties of nanomaterials. In this review, we discuss the nanoarchitectonics of nanomaterials regarding enhanced photothermal properties and their application in LFAs. Initially, we discuss

• sensitivity is an important research area. The nanoscale architecture, including shape, size, composition, and surface properties, is expected to play a major role in the photothermal properties of nanomaterials [26]. The nanoscale architecture is not only responsible for the optical characteristics of the

Conjugated photothermal materials and structure design for solar steam generation

• Chia-Yang Lin and
• Tsuyoshi Michinobu

Beilstein J. Nanotechnol. 2023, 14, 454–466, doi:10.3762/bjnano.14.36

• generated to yield robust PTM materials suitable for SSG applications. Since DPP-DCV and DPP-INCN exhibited stronger ICT interactions than DPP-H, they showed better photothermal properties (Figure 4a). There results highlight the significance of the chemical structure. DPP-H has solubilizing siloxane chains

Concentration-dependent photothermal conversion efficiency of gold nanoparticles under near-infrared laser and broadband irradiation

• Vikas,
• Raj Kumar and
• Sanjeev Soni

Beilstein J. Nanotechnol. 2023, 14, 205–217, doi:10.3762/bjnano.14.20

• applications. Keywords: broadband irradiation; gold nanoparticles; laser; near-infrared; photothermal conversion efficiency; plasmonics; Introduction Plasmonic photothermal properties of gold nanoparticles (GNPs) are useful for a variety of applications including those in biomedicine, such as drug delivery

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

• Yuran Wang,
• Xudong Li,
• Haijun Chen and
• Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

• -LNPs with optimized particle size and polydispersity index (PDI), and then mixed BDP with Au-LNPs to obtain both Au- and BDP-grafted LNPs (AB-LNPs). The physiochemical characteristics, the photothermal properties, and the stabilities of AB-LNPs were studied in detail. The cellular uptake efficiency and

• taken out to measure the amount of the released drug by UV–vis spectroscopy, and an equal volume of fresh release medium was added to keep the volume constant. Photothermal measurement for AB-LNPs To study the photothermal properties of AB-LNPs, different concentrations of AB-LNPs with BDP

• . 10 nm were observed for AB-LNPs. AB-LNPs showed a rice-like shape, which was similar to that of LNPs and Au-LNPs, indicating that grafting both Au3+ and BDP onto LNPs did not destroy the structure of the preformed LNPs. Photothermal properties of AB-LNPs To evaluate the photothermal properties of AB

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• been shown that a novel protein-based nanoparticle with enhanced photothermal effect has been obtained for antitumor therapy using metal ions, proteins, and photosensitizers as building blocks [69]. The integration of metal ions significantly improved the structural stability and photothermal

• properties of the nanoparticles [69]. The use of amino acids coordinated with metal ions and the encapsulation of guest molecule photosensitizers have also achieved encouraging results. Zhang et al. [70] developed an antitumor photodynamic therapy (PDT) nanoparticle based on the coordination of modified

Use of nanosystems to improve the anticancer effects of curcumin

• Andrea M. Araya-Sibaja,
• Norma J. Salazar-López,
• Krissia Wilhelm Romero,
• José R. Vega-Baudrit,
• J. Abraham Domínguez-Avila,
• Carlos A. Velázquez Contreras,
• Ramón E. Robles-Zepeda,
• Mirtha Navarro-Hoyos and
• Gustavo A. González-Aguilar

Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78

• promising application of gold nanostructures with CUR-loaded alginate microgels, which showed photothermal properties. High CUR retention and preferential toxicity against cancerous cells was also shown. The photoactive agent, wavelength, time of exposure, and distance to the light source are important

Rapid controlled synthesis of gold–platinum nanorods with excellent photothermal properties under 808 nm excitation

• Jialin Wang,
• Qianqian Duan,
• Min Yang,
• Boye Zhang,
• Li Guo,
• Pengcui Li,
• Wendong Zhang and
• Shengbo Sang

Beilstein J. Nanotechnol. 2021, 12, 462–472, doi:10.3762/bjnano.12.37

• proposed. The synthesized Au@Pt NRs have a longitudinal LSPR wavelength of 812 nm, which is very close to a common laser wavelength of 808 nm. The Au@Pt NRs exhibit excellent photothermal properties when irradiated with a laser. The temperature increased by more than 36 °C after irradiation for 10 min

• , with a PCE of about 78.77%, which is much higher than that of AuNRs (57.33%). In addition, even after four on/off cycles, the Au@Pt NRs are able to maintain the photothermal properties and retain their optical properties, indicating that they have excellent photothermal stability and reusability

• have not yet clearly evaluated the photothermal properties of their products. The key factors to be considered when selecting noble metal nanoscale PTAs are the wavelength of the LSPR peak, PCE, and photothermal stability. Based on previous research results from a preliminary experiment of Pt

Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms

• Mykola Borzenkov,
• Piersandro Pallavicini,
• Angelo Taglietti,
• Laura D’Alfonso,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2020, 11, 1134–1146, doi:10.3762/bjnano.11.98

• least if used under given irradiance limits, e.g., 0.32 W/cm2 at 800 nm) [2][34]. Moreover, stable and reproducible photothermal properties will bring additional advantages for efficient in situ sterilization. Therefore, in this review we focus on the application of photothermally active nanoparticles

• materials, nanoscale metal chalcogenides (Cu2−xE, E = S, Se, Te), transition metal dichalcogenide nanostructures (e.g., WS2, MoS2), metal-oxide nanoparticles (e.g., WO3), and nanoscale coordination compounds (e.g., Prussian blue nanoparticles) [33][36][37][38]. The photothermal properties of these

• nanoparticles are synthesized, resulting in nanoparticles with different dimensions and shape. On the other hand, the nanoparticle surface chemistry as well as the surrounding environment exert a weaker influence on the plasmonic properties. For the non-plasmonic nanoparticles, the photothermal properties are

Polydopamine-coated Au nanorods for targeted fluorescent cell imaging and photothermal therapy

• Boris N. Khlebtsov,
• Andrey M. Burov,
• Timofey E. Pylaev and
• Nikolai G. Khlebtsov

Beilstein J. Nanotechnol. 2019, 10, 794–803, doi:10.3762/bjnano.10.79

• photothermal effects Notably, the AuNR-PDA-R123-folate not only served as fluorescent imaging agent, but it was also employed as a NIR light absorber in photothermal laser therapy. To compare the photothermal properties of PDA-coated nanorods with PEG-coated nanorods, we added 200 µL of AuNR-PDA-R123-folate or

Hybrid Au@alendronate nanoparticles as dual chemo-photothermal agent for combined cancer treatment

• Anouchka Plan Sangnier,
• Romain Aufaure,
• Laurence Motte,
• Claire Wilhelm,
• Erwann Guenin and
• Yoann Lalatonne

Beilstein J. Nanotechnol. 2018, 9, 2947–2952, doi:10.3762/bjnano.9.273

• , in the form of PTT, we first evaluated the specific photothermal properties of Au@alendronate NPs. In cancer therapy, it is desirable to use NPs that are active in the near-infrared (NIR) region to minimize light absorption of the laser radiation by surrounding tissues [27][34]. The plasmonic

• concentrations, reaching very high values (over 8000 W/g) at low concentrations. These photothermal properties are in good agreement with those of other thermal agents [23] and show the applicability of Au@alendronate gold NPs as potential photothermal agents. The colloidal stability of Au@alendronate NPs at

• physiological pH values and their photothermal properties within the NIR first biological window allowed us to further consider their study in a biological environment. Au@alendronate NPs antitumor activity PC3 human prostate adenocarcinoma cells were selected to explore the potential of Au@alendronate NPs as

Time-resolved universal temperature measurements using NaYF₄:Er³⁺,Yb³⁺ upconverting nanoparticles in an electrospray jet

• Kristina Shrestha,
• Arwa A. Alaulamie,
• Ali Rafiei Miandashti and
• Hugh H. Richardson

Beilstein J. Nanotechnol. 2018, 9, 2916–2924, doi:10.3762/bjnano.9.270

• temperature measurements inside an electrospray Taylor cone. Measuring temperature with nanoscale spatial resolution is not easy. Nanoscale temperature measurements and properties have been modeled [7][8][9] and measured using lanthanide emission [5][10][11][12][13][14][15], photothermal properties [16][17

Fabrication of photothermally active poly(vinyl alcohol) films with gold nanostars for antibacterial applications

• Mykola Borzenkov,
• Maria Moros,
• Claudia Tortiglione,
• Serena Bertoldi,
• Nicola Contessi,
• Silvia Faré,
• Angelo Taglietti,
• Agnese D’Agostino,
• Piersandro Pallavicini,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2018, 9, 2040–2048, doi:10.3762/bjnano.9.193

• , Piazza dell’AteneoNuovo, 20126, Milan, Italy 10.3762/bjnano.9.193 Abstract The unique photothermal properties of non-spherical gold nanoparticles under near-infrared (NIR) irradiation find broad application in nanotechnology and nanomedicine. The combination of their plasmonic features with widely used

• biocompatible poly(vinyl alcohol) (PVA) films can lead to novel hybrid polymeric materials with tunable photothermal properties and a wide range of applications. In this study, thin PVA films containing highly photothermally efficient gold nanostars (GNSs) were fabricated and their properties were studied. The

• antibacterial films and coatings. Keywords: antibacterial properties; gold nanostars; photothermal effect; poly(vinyl alcohol) films; Introduction The photothermal properties of non-spherical gold nanoparticles possessing localized surface plasmon resonance (LSPR) located in NIR range has already been

Photothermal effect of gold nanostar patterns inkjet-printed on coated paper substrates with different permeability

• Mykola Borzenkov,
• Anni Määttänen,
• Petri Ihalainen,
• Maddalena Collini,
• Elisa Cabrini,
• Giacomo Dacarro,
• Piersandro Pallavicini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2016, 7, 1480–1485, doi:10.3762/bjnano.7.140

• output [25][26]. The photothermal properties of printed gold nanoparticle patterns on paper substrates have not been fully explored yet, and this is the main aim of this study. We reported recently that GNS patterns inkjet-printed onto semi-permeable paper display a substantial photothermal effect with

• substrates has a significant impact on the photothermal properties of the printed patterns. On the non-permeable substrate, a significant photothermal effect was achieved with a sixth of ink compared to the permeable substrate. This finding is particularly useful in definining the minimum amount of gold to

Near-infrared dye loaded polymeric nanoparticles for cancer imaging and therapy and cellular response after laser-induced heating

• Tingjun Lei,
• Alicia Fernandez-Fernandez,
• Romila Manchanda,
• Yen-Chih Huang and
• Anthony J. McGoron

Beilstein J. Nanotechnol. 2014, 5, 313–322, doi:10.3762/bjnano.5.35

• (wavelength 700–900 nm) are promising for in vivo imaging because light at these wavelengths has minimal absorption by tissue [6][7]. Moreover, some NIR dyes such as indocyanine green (ICG) can be used as both imaging agents and heat generators due to their unique photothermal properties. However, ICG has a