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Search for "polylactic acid" in Full Text gives 16 result(s) in Beilstein Journal of Nanotechnology.

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

  • Iqra Zainab,
  • Zohra Naseem,
  • Syeda Rubab Batool,
  • Muhammad Waqas,
  • Ahsan Nazir and
  • Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

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  • electrospun polymer fibers is affected by electric field intensity, solution viscosity, charge density of the solution, and solution supply rate [56]. The size of the fibers also affects the performance of electrospun nanofiber composites [57]. Numerous polymers and precursors including polylactic acid, PU
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Published 24 Apr 2025

Recent advances in photothermal nanomaterials for ophthalmic applications

  • Jiayuan Zhuang,
  • Linhui Jia,
  • Chenghao Li,
  • Rui Yang,
  • Jiapeng Wang,
  • Wen-an Wang,
  • Heng Zhou and
  • Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

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  • damage to surrounding tissues due to inadequate control over the heat distribution [100][101][102][103][104][105]. Innovations in this field have led to the development of transparent polylactic acid (PLA) thin films with embedded iron oxide nanoclusters prepared via spin coating [51]. The efficient
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Published 17 Feb 2025

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

  • Le Thi Le,
  • Hue Thi Nguyen,
  • Liem Thanh Nguyen,
  • Huy Quang Tran and
  • Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

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  • Sciences, Phenikaa University, Hanoi 12116, Vietnam 10.3762/bjnano.15.7 Abstract Hydrophobic berberine powder (BBR) and hydrophilic BBR nanoparticles (BBR NPs) were loaded into an electrospun polylactic acid (PLA) nanofiber scaffold for modulating the release behavior of BBR in an aqueous medium. The BBR
  • systems, and tissue engineering, according to the requirement of BBR concentration for the desired therapeutic effects. Keywords: antibacterial activity; berberine; drug-release system; electrospun nanofiber; polylactic acid; Introduction Medicinal plants have various biologically active compounds, such
  • strongly affect the release behavior of the drug from nanofiber scaffolds [14][17][18][19]. Polylactic acid (PLA), a synthetic polymer that has been approved by the FDA for biomedical usage, is commonly used for drug delivery systems due to its biocompatibility and biodegradability [20]. Yuan et al. [17
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Published 12 Jan 2024

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

  • Se-Kwon Kim,
  • Sesha Subramanian Murugan,
  • Pandurang Appana Dalavi,
  • Sebanti Gupta,
  • Sukumaran Anil,
  • Gi Hun Seong and
  • Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

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  • . Different kinds of polymeric materials have been utilized including chitosan, alginate, fucoidan, carrageenan, and ulvan from natural polymeric materials. Polycaprolactone (PCL), poly ᴅ,ʟ-lactic-co-glycolic acid (PLGA), and polylactic acid (PLA) have been extensively studied with hydroxyapatite to develop
  • collagen, they develop an interlinked molecular framework with load-bearing applications and have superior mechanical qualities and biological advantages [57]. A further study reported that carbon nanotubes combined with synthetic polymers of poly-ʟ-lactide acid, polylactic acid
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Published 29 Sep 2022

Fabrication and testing of polymer microneedles for transdermal drug delivery

  • Vahid Ebrahiminejad,
  • Zahra Faraji Rad,
  • Philip D. Prewett and
  • Graham J. Davies

Beilstein J. Nanotechnol. 2022, 13, 629–640, doi:10.3762/bjnano.13.55

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  • their biocompatibility, biodegradability, and potential for mass production [12]. Polymers such as polylactic acid (PLA), poly(methyl methacrylate) (PMMA), poly(carbonate), cyclic olefin copolymer (COC) and cycloolefin polymers (COP), polystyrene, and SU-8 photoresists, have all been used for
  • the viscoelastic nature of Zeonor 1060R, the initial near-tip failure was indistinct on the force-displacement diagram. These mechanical responses have been previously observed during compression tests on polymeric MN materials, including carboxymethyl cellulose (CMC) and polylactic acid (PLA) [1][38
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Published 08 Jul 2022

Electrostatic pull-in application in flexible devices: A review

  • Teng Cai,
  • Yuming Fang,
  • Yingli Fang,
  • Ruozhou Li,
  • Ying Yu and
  • Mingyang Huang

Beilstein J. Nanotechnol. 2022, 13, 390–403, doi:10.3762/bjnano.13.32

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  • kV output voltage using 3D printed conductive polylactic acid polymer. In 2021, they [101] integrated a lithium niobate crystal, a piezoelectric cantilever switch, and a capacitive load into a single printed circuit board (PCB). The output voltage ranges from 15.5 to 1480 V, and the cantilever switch
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Published 12 Apr 2022

Effects of drug concentration and PLGA addition on the properties of electrospun ampicillin trihydrate-loaded PLA nanofibers

  • Tuğba Eren Böncü and
  • Nurten Ozdemir

Beilstein J. Nanotechnol. 2022, 13, 245–254, doi:10.3762/bjnano.13.19

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  • area, high encapsulation efficiency, high porosity, and superior mechanical properties [5][6][7]. In our study, FDA-approved polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA), which are frequently preferred polymers in the production of polymeric nanofibers, were used because they are
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Published 21 Feb 2022

An overview of microneedle applications, materials, and fabrication methods

  • Zahra Faraji Rad,
  • Philip D. Prewett and
  • Graham J. Davies

Beilstein J. Nanotechnol. 2021, 12, 1034–1046, doi:10.3762/bjnano.12.77

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  • and sizes for a wide range of applications. Metals such as titanium [61][62], stainless steel [58][63][64], silicon [65][66][67], ceramics [68][69], biodegradable polymers such as polylactic acid (PLA) [70], PLGA [71], and polyglycolic acid (PGA) [72], and non-degradable polymers such as
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Published 13 Sep 2021

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

  • Varsha Sharma and
  • Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

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  • at pH 4.5 resulted in a thin and smooth capsule [27]. Similarly, biodegradable cores of polylactic acid polymer have also been investigated with several PEs, but limited by poor colloidal stability [28]. In contrast to the above-mentioned studies, inorganic templates such as carbonates are larger in
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Published 27 Mar 2020

Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine

  • Valentina Francia,
  • Daphne Montizaan and
  • Anna Salvati

Beilstein J. Nanotechnol. 2020, 11, 338–353, doi:10.3762/bjnano.11.25

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  • -polylactic acid particles entered, at least partially, by clathrin-mediated endocytosis and macropinocytosis [143]. It is important to mention that many studies investigating the effect of charge or other nanomaterial properties on cellular interactions were performed in the absence of proteins from
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Published 14 Feb 2020

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

  • Sebastian Pieper,
  • Hannah Onafuye,
  • Dennis Mulac,
  • Jindrich Cinatl Jr.,
  • Mark N. Wass,
  • Martin Michaelis and
  • Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 2062–2072, doi:10.3762/bjnano.10.201

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  • . To investigate whether easy-to-prepare nanoparticles made of well-tolerated polymers may circumvent transporter-mediated drug efflux, we prepared poly(lactic-co-glycolic acid) (PLGA), polylactic acid (PLA), and PEGylated PLGA (PLGA-PEG) nanoparticles loaded with the ABCB1 substrate doxorubicin by
  • carriers for anticancer drugs. Here, we prepared and directly compared the effects of doxorubicin-loaded polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA) nanoparticles in neuroblastoma cells. PLA and PLGA are well-known ingredients of FDA- and EMA-approved drugs for human use [10][11] and are
  • polyethylene glycol (PEG) and PLGA (PLGA-PEG) and polylactic acid (PLA), respectively, were prepared in the presence of doxorubicin by either emulsion diffusion or solvent displacement technique. The resulting particle diameters are presented in Figure 1. Emulsion diffusion (173.5 ± 5.9 nm) and solvent
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Published 29 Oct 2019

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

  • Hannah Onafuye,
  • Sebastian Pieper,
  • Dennis Mulac,
  • Jindrich Cinatl Jr.,
  • Mark N. Wass,
  • Klaus Langer and
  • Martin Michaelis

Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

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  • bind to doxorubicin via its amino group. Notably, the results differ from a recent similar study in which nanoparticles prepared from poly(lactic-co-glycolic acid) (PLGA) or polylactic acid (PLA), two other biodegradable materials approved by the FDA and EMA for human use [27][28], did not bypass ABCB1
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Published 14 Aug 2019

Effect of electrospinning process variables on the size of polymer fibers and bead-on-string structures established with a 23 factorial design

  • Paulina Korycka,
  • Adam Mirek,
  • Katarzyna Kramek-Romanowska,
  • Marcin Grzeczkowicz and
  • Dorota Lewińska

Beilstein J. Nanotechnol. 2018, 9, 2466–2478, doi:10.3762/bjnano.9.231

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  • beads). There are only a few research articles showing the application of this method. Coles et al. examined the influence of various process parameters on polylactic acid and poly(vinyl alcohol) electrospun fibers [26]. Nottelet et al. used factorial design to optimize the manufacture of small diameter
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Published 17 Sep 2018

Nanoconjugates of a calixresorcinarene derivative with methoxy poly(ethylene glycol) fragments for drug encapsulation

  • Alina M. Ermakova,
  • Julia E. Morozova,
  • Yana V. Shalaeva,
  • Victor V. Syakaev,
  • Aidar T. Gubaidullin,
  • Alexandra D. Voloshina,
  • Vladimir V. Zobov,
  • Irek R. Nizameev,
  • Olga B. Bazanova,
  • Igor S. Antipin and
  • Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 2057–2070, doi:10.3762/bjnano.9.195

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  • usage of fragments of known biocompatible polymers, such as PEG, polylactic acid and polycaprolactone. The functionalization of the calixresorcinarene platform with such fragments leads to the formation of hyperbranched three-dimensional structures, which exhibit a higher solubility, lower viscosity and
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Published 27 Jul 2018

Organic and inorganic–organic thin film structures by molecular layer deposition: A review

  • Pia Sundberg and
  • Maarit Karppinen

Beilstein J. Nanotechnol. 2014, 5, 1104–1136, doi:10.3762/bjnano.5.123

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Published 22 Jul 2014

Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique

  • Alina Maria Holban,
  • Valentina Grumezescu,
  • Alexandru Mihai Grumezescu,
  • Bogdan Ştefan Vasile,
  • Roxana Truşcă,
  • Rodica Cristescu,
  • Gabriel Socol and
  • Florin Iordache

Beilstein J. Nanotechnol. 2014, 5, 872–880, doi:10.3762/bjnano.5.99

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  • S.C. Metav-CD S.A., 31 Rosetti Str., 020015 Bucharest, Romania Flow Cytometry and Cell Therapy Laboratory, Institute of Cellular Biology and Pathology “Nicolae Simionescu” (ICBP), Bucharest, Romania 10.3762/bjnano.5.99 Abstract We report on the fabrication of thin coatings based on polylactic acid
  • nanoparticles; nanospheres; P. aeruginosa; polylactic acid; S. aureus; Introduction Driven by more and more microbial antibiotic resistance, alternative therapeutic approaches are emerging [1][2][3][4]. Polar and nonpolar, functionalized and non-functionalized magnetite nanostructures have proven successfully
  • Polylactic acid (PLA), polyvinyl alcohol (PVA), chitosan (CS), eugenol (EUG), FeCl3, FeSO4·7H2O, NH4OH (25%), chloroform and n-hexane were purchased from Sigma-Aldrich. Preparation of magnetite nanostructures A well-known procedure described in our previous work was used to synthesize the magnetite
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Published 18 Jun 2014
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