Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• immunity and enhancing cancer immunotherapy outcomes. Additionally, natural compounds such as berberine and quercetin can modulate macrophage polarization by inhibiting M1 pathways or promoting M2 activity, highlighting the therapeutic potential of targeting macrophage states in inflammatory and

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• , Carlo Erba, France); 0–5 min linear, solution A was adjusted from 10% to 40%, then to 50% over the next 3 min; for the last 12 min, the ratio of solutions was maintained isocratic. Ethanol solutions of quercetin (Sigma-Aldrich, Germany), rutin (Sigma-Aldrich, Germany), apigenin (Sigma-Aldrich, Germany

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• 21 days than free CUR. Quercetin Quercetin (QCT) is a flavonoid found in many fruits, vegetables, leaves, seeds, and grains. It is particularly abundant in onions, apples, berries, tea, and red wine [84]. This natural polyphenolic compound has gained attention for its diverse therapeutic effects. QCT

• exhibits significant anti-inflammatory, antioxidant, antiviral, anticancer, cardioprotective, neuroprotective, and anti-allergic properties [85][86]. QCT belongs to the BCS class-II drugs and shows very poor solubility. The low solubility of quercetin in aqueous environments leads to poor dissolution and

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• characterization of quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles (Ch/Q- and Ch/CA-Ag NPs), and their antibacterial and anticancer activities. The formation of Ch/Q- and Ch/CA-Ag NPs has been confirmed by ultraviolet–visible (UV–vis) spectroscopy, Fourier-transform

• infrared (FTIR) spectroscopy, and transmission electron microscopy (TEM). The characteristic surface plasmon resonance (SPR) absorption band has been found at 417 and 424 nm for Ch/Q- and Ch/CA-Ag NPs, respectively. The formation of a chitosan shell comprising quercetin and caffeic acid, which surround the

• (P. aeruginosa and E. coli) and Gram-positive (S. aureus and S. epidermidis) bacteria was determined, and dose-dependent antibacterial effects were found. Keywords: Ag NPs; anticancer and antibacterial effects; caffeic acid; chitosan; one-pot synthesis; quercetin; U-118 MG and ARPE-19 cells

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• effectively increased in tumor tissues, and the side effects on normal tissues can be significantly reduced [92]. Quercetin (QT), a flavonoid with various functions, such as antitumor activity and radiosensitization, has been loaded into NPs and encapsulated by cancer cell membranes to further study its

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• ]. Non-steroidal anti-inflammatory drugs (e.g., quercetin, ibuprofen, dexamethasone, aspirin, indomethacin) have been successfully loaded and eluted locally from TNTs in vitro in titania-based implants. Surface modifications such as biopolymer coating, polymeric micelle encapsulation, and periodic

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

• micelle method has served as a common approach for the synthesis of AgNPs throughout the past two decades [152]. Regular reducing agents used in this method include sodium borohydride (NaBH4) [236], hydrazine (N2H4) [237], glucose [238], and quercetin [152][239], to name a few. The size and size

Nanoconjugates of a calixresorcinarene derivative with methoxy poly(ethylene glycol) fragments for drug encapsulation

• Alina M. Ermakova,
• Julia E. Morozova,
• Yana V. Shalaeva,
• Victor V. Syakaev,
• Aidar T. Gubaidullin,
• Alexandra D. Voloshina,
• Vladimir V. Zobov,
• Irek R. Nizameev,
• Olga B. Bazanova,
• Igor S. Antipin and
• Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 2057–2070, doi:10.3762/bjnano.9.195

• nanoassociates that are able to encapsulate organic substrates of different hydrophobicity, including drugs (doxorubicin, naproxen, ibuprofen, quercetin). The micelles of the macrocycle slowed down the release of the hydrophilic substrates in vitro. In physiological sodium chloride solution and phosphate

• encapsulation of hydrophobic substrates The encapsulation of model compounds of different hydrophobicity by macrocycle 3 was studied (Table 2). These compounds were doxorubicin (Dox), an anthracycline antitumor antibiotic, quercetin (QC), a flavonol that exhibits decongestant, antispasmodic, antihistaminic

• , Orange OT, ibuprofen, naproxen sodium, naproxen were purchased from Sigma-Aldrich, rhodamine B was purchased from Acros. Quercetin and doxorubicin hydrochloride were kindly supplied by Prof. E. Kh. Kazakova. Doxorubicin hydrochloride was hydrophobized by the method reported in [37]. Tosylated mPEG-550 2