Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• , effective encapsulation, pH-responsive release, and enhanced stability. Eudragit RS 100 is a copolymer of ethyl acrylate, methyl methacrylate, and a low proportion of methacrylic acid ester with quaternary ammonium groups. It is known for its mucoadhesive properties [16], which are independent of the site

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• and controlled release of the encapsulated drugs. Among all PLHNPs, these hybrid nanocarriers show the highest stability in the biological fluids and stimuli-responsive release of encapsulated drugs. In addition, the polymeric cage protects the drug from the harsh environment, and encapsulated drugs

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

• Yuran Wang,
• Xudong Li,
• Haijun Chen and
• Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

• attributed to the increased solution temperature, which accelerated the dissociation of BDP from AB-LNPs. There are no obvious differences between the release profiles of AB-LNPs at pH 5.5 and at pH 7.4, indicating that AB-LNPs do not exhibit pH-responsive drug release. The stimulus-responsive release

• efficiency (Figure 1). AB-LNPs also showed good stability under physiological conditions and demonstrated laser-responsive release characteristics (Figure 3). BDP grafted on the AB-LNPs could generate greatly enhanced cellular uptake in cancer cells (Figure 4). Due to the enhanced permeability and retention

• effect (EPR) of tumors, AB-LNPs will have a good tumor accumulation ability. The enhanced cellular uptake efficiency and the laser-responsive release properties of AB-LNPs could further improve the anti-tumor effects. The clinically applicable temperatures for hyperthermia range from 43 to 47 °C since

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• metal nanoparticles under physiological conditions and the abrupt responsive release upon pH and glutathione changes. The half-life of Ce6 in Fmoc-H/Zn2+/Ce6 (8.71 h) and Z-HF/Zn2+/Ce6 (6.33 h) was much longer than that of unencapsulated Ce6 (3.69 h), according to the fitting results of the

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

PEG/PEI-functionalized single-walled carbon nanotubes as delivery carriers for doxorubicin: synthesis, characterization, and in vitro evaluation

• Shuoye Yang,
• Zhenwei Wang,
• Yahong Ping,
• Yuying Miao,
• Yongmei Xiao,
• Lingbo Qu,
• Lu Zhang,
• Yuansen Hu and
• Jinshui Wang

Beilstein J. Nanotechnol. 2020, 11, 1728–1741, doi:10.3762/bjnano.11.155

• [30] exhibited sustained release at pH 7.4, and responsive release under relatively acidic condition, which was similar to our results. In this study, a series of experimental observations with MCF-7 cells were conducted and the results verify the delivery capacity and in vitro antitumor activity

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• healthy and Neiman–Pick-diseased patients. The results showed significant differences in the lysosomal population in cells between the diseased and the healthy state. The group of Andersen reported a DNA nanobox with controllable lid, and its dynamic nature potentially facilitated the stimuli-responsive

• release of cargo molecules into the targeted area [59]. In another interesting design, DNA origami nanorobots were implanted into living systems and executed DNA-based biocomputing via dynamic cell-associated interactions [60]. An alteration of the physiological pH can be indicative of a diseased

Closed polymer containers based on phenylboronic esters of resorcinarenes

• Tatiana Yu. Sergeeva,
• Rezeda K. Mukhitova,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Polina D. Klypina,
• Albina Y. Ziganshina and
• Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 1594–1601, doi:10.3762/bjnano.9.151

• release of dye is achieved by lowering the pH value to 3 or by adding glucose. Keywords: boronic acid; polymer nanocontainer; resorcinarene; responsive release; Introduction Boronic acids effectively interact with diols [1][2][3][4] that have found application in various fields: in the recognition and