Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• past decade demonstrating how these polymers improve gene silencing efficiencies, particularly in cancer and neurodegenerative disease models. Despite the progress achieved, barriers such as immunogenicity, delivery limitations, and scalability still need to be overcome for broader clinical application

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• improve the performance and scalability for wider use in real-world situations. Keywords: antibiotics; degradation pathways; heterojunctions; mechanisms; photocatalysts; semiconductor; Introduction Antibiotics are chemical substances used to treat bacterial infections in humans, animals, aquaculture

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation

• Abhishek Das,
• Mangababu Akkanaboina,
• Jagannath Rathod,
• R. Sai Prasad Goud,
• Kanaka Ravi Kumar,
• Raghu C. Reddy,
• Ratheesh Ravendran,
• Katia Vutova,
• S. V. S. Nageswara Rao and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1639–1653, doi:10.3762/bjnano.15.129

• polarization. The available literature on LIPSS suggests that there will be no changes in the spacing or other morphological features except the orientation of the LIPSS with respect to the polarisation. Combined with the picosecond laser’s high precision processing and industrial scalability, Hf is a

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

• Fabio Le Piane,
• Mario Vozza,
• Matteo Baldoni and
• Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

• materials research is cloud computing. Cloud-based platforms provide on-demand access to HPC resources and large databases and infrastructures. Cloud-based infrastructures for materials research offer scalability, flexibility, and accessibility, empowering researchers to collaborate, analyze data, and

• has emerged as a pivotal catalyst, revolutionizing the infrastructures for data [28]. Cloud technologies represent the most efficient and dynamic means to facilitate the seamless sharing of knowledge across diverse platforms. The inherent scalability, flexibility, and accessibility of cloud-based

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• (QIP) systems. Despite the challenges such as fabrication complexity [6] and loss mitigation scalability to complex circuits [7], the potential benefits of DBRs for QIP applications continue to drive research and development in this field [8]. As fabrication techniques and material systems develop

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• adjustments to their shape [185]. This adaptable structure can inspire the development of aerospace vehicles with enhanced axial scalability and bending properties [185]. Incorporating a morphing structure inspired by the Hymenoptera metasoma could lead to the creation of supermaneuverable flight systems

Quantum-to-classical modeling of monolayer Ge₂Se₂ and its application in photovoltaic devices

• Anup Shrivastava,
• Shivani Saini,
• Dolly Kumari,
• Sanjai Singh and
• Jost Adam

Beilstein J. Nanotechnol. 2024, 15, 1153–1169, doi:10.3762/bjnano.15.94

• -term instability, poor device scalability, and the use of toxic compounds, have yet to be resolved [6]. Recent advancements have seen the integration of two-dimensional (2D) materials with PSCs, opening new avenues for enhancing their performance and addressing current challenges with the PSCs [7][8

• ]. Integrating 2D materials in PSCs can improve their performance. The 2D materials can provide protective layers that work like a shield to the perovskite materials to protect them from environmental degradation caused by moisture and oxygen and provide better device scalability to the PSCs, which makes large

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• scalability, which improves reliability as a hot electron impact is significantly reduced at lower operating bias voltages. Hence, it offers higher power efficiency and reliability. 2.2.21 Overlap gate-on-drain TFET-based biosensors. An overlap gate-on-drain (OGOD) TFET-based biosensor has been reported by

• network (NN) could be used to predict device parameters and performance of 3D and 2D FET-based biosensors. NN and ML could be employed to predict and study the scalability of FET biosensors. Also, they could be applied to the fabrication process of these types of biosensors. Therefore, AI algorithms and

Green synthesis of biomass-derived carbon quantum dots for photocatalytic degradation of methylene blue

• Dalia Chávez-García,
• Mario Guzman,
• Viridiana Sanchez and
• Rubén D. Cadena-Nava

Beilstein J. Nanotechnol. 2024, 15, 755–766, doi:10.3762/bjnano.15.63

• quantum dots (CQDs) through a hydrothermal method using biomass from watermelon peels and grape pomace. This method is chosen for its ease of production, low cost, and scalability. We aim to evaluate the potential of CQDs as catalysts in the photocatalytic degradation of methylene blue (MB) dye in

Industrial perspectives for personalized microneedles

• Remmi Danae Baker-Sediako,
• Benjamin Richter,
• Matthias Blaicher,
• Michael Thiel and
• Martin Hermatschweiler

Beilstein J. Nanotechnol. 2023, 14, 857–864, doi:10.3762/bjnano.14.70

• realize greater efficacy while also maintaining scalability. For example, snake fangs are hollow and asymmetrically grooved teeth optimized to deliver liquid venom. Researchers can use the bio-inspired hollow design to transdermally deliver drugs that must remain in liquid form during administration [39

Microneedle patches – the future of drug delivery and vaccination?

• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2023, 14, 494–495, doi:10.3762/bjnano.14.40

• originally developed for the microelectronics industry; they were inevitably made from silicon. Since then, silicon MNs have been largely abandoned in favour of polymer versions because of their superior mechanical properties, biocompatibility, ease of manufacture, and ultimate scalability [5][6]. Polymer

Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide

• Mustafa Gungormus

Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25

• structures, high cost, labor-intensiveness, resolution limits, and high throughput time limit the scalability [8]. Self-assembly allows to circumvent some of the constraints of the top-down techniques to obtain ordered 2D or 3D nanostructures. Self-assembly, however, presents challenges of its own. One major

A novel approach to pulsed laser deposition of platinum catalyst on carbon particles for use in polymer electrolyte membrane fuel cells

• Bogusław Budner,
• Wojciech Tokarz,
• Sławomir Dyjak,
• Andrzej Czerwiński,
• Bartosz Bartosewicz and
• Bartłomiej Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 190–204, doi:10.3762/bjnano.14.19

• applications. The method developed still requires additional investigations on production scalability, repeatability, and automation of the Pt deposition process. It is also crucial to test the chemical stability of the material in the working polymer fuel cell system over a long period. Experimental Materials

Systematic studies into uniform synthetic protein nanoparticles

• Nahal Habibi,
• Ava Mauser,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22

• tuned by changing their respective protein-to-protein ratios. Future efforts will include the application of these methods to a range of nanomedicine applications and further studies aimed at correlating these properties with SPNP performance in vitro and in vivo. The direct scalability of the

Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material

• Yuri B. Matos,
• Rodrigo S. Romanus,
• Mattheus Torquato,
• Edgar H. de Souza,
• Rodrigo L. Villanova,
• Marlene Soares and
• Emilson R. Viana

Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63

• (Ag+) into bacterial cells [12]. However, a large-scale industrial usage of Ag-NPs is still difficult because most synthesis techniques used in labs are unsuitable for commercial use. The main issues are high procedural complexity and elevated cost, which jeopardize scalability efforts fundamental to

TiO_x/Pt₃Ti(111) surface-directed formation of electronically responsive supramolecular assemblies of tungsten oxide clusters

• Marco Moors,
• Yun An,
• Agnieszka Kuc and
• Kirill Yu. Monakhov

Beilstein J. Nanotechnol. 2021, 12, 203–212, doi:10.3762/bjnano.12.16

• oxide; tungsten oxide; Introduction Molecular electronics has developed to a fast-growing research field in the past decades. Aspects such as low-cost fabrication and potentially high scalability down to the level of single molecules, resulting directly in a very low power consumption, make this type

Amorphized length and variability in phase-change memory line cells

• Nafisa Noor,
• Sadid Muneer,
• Raihan Sayeed Khan,
• Anna Gorbenko and
• Helena Silva

Beilstein J. Nanotechnol. 2020, 11, 1644–1654, doi:10.3762/bjnano.11.147

• memory (PCM) is an emerging non-volatile memory technology with high endurance, high speed, and good scalability. PCM relies on the change in phase of a nanoscale volume of a chalcogenide material sandwiched between two electrodes. The phase of the material can be switched between the high-resistivity

One-step synthesis of carbon-supported electrocatalysts

• Sebastian Tigges,
• Nicolas Wöhrl,
• Ivan Radev,
• Ulrich Hagemann,
• Markus Heidelmann,
• Thai Binh Nguyen,
• Stanislav Gorelkov,
• Stephan Schulz and
• Axel Lorke

Beilstein J. Nanotechnol. 2020, 11, 1419–1431, doi:10.3762/bjnano.11.126

• agglomeration (i.e., highly porous supports) [16]. After years of development, conventional synthesis methods still have problems meeting the requirements for scalability of the synthesis and long-term stability of the resulting catalyst. In this work, we report on a novel one-step synthesis approach that not

Hexagonal boron nitride: a review of the emerging material platform for single-photon sources and the spin–photon interface

• Stefania Castelletto,
• Faraz A. Inam,
• Shin-ichiro Sato and
• Alberto Boretti

Beilstein J. Nanotechnol. 2020, 11, 740–769, doi:10.3762/bjnano.11.61

• unique. The search for other platforms is mainly motivated by either scalability or manufacturability within a monolithic platform fabrication or opportunities to facilitate hybrid integration of quantum materials with existing mature devices (hybrid approach). However, there are other materials that are

• SP and spin-controlled point defects in this material [62]. The host material synthesis is also relevant, as the possibility to study single NVs in diamond and similar defects in SiC is based on the commercial availability of high-purity materials. Scalability is instead related to the host material

• /compatibility of the active quantum source and the device in use, and they have limitations in terms of scalability. The type of point defects that should be addressed is also a key element and is generally substitutional dopants, native vacancies, and dopant-vacancy complexes. The space of possible defects is

Exfoliation in a low boiling point solvent and electrochemical applications of MoO₃

• Matangi Sricharan,
• Bikesh Gupta,
• Sreejesh Moolayadukkam and
• H. S. S. Ramakrishna Matte

Beilstein J. Nanotechnol. 2020, 11, 662–670, doi:10.3762/bjnano.11.52

• crucial to exfoliate MoO3 for improved performance in a variety of applications. Liquid-phase exfoliation (LPE) has been shown to be an effective technique for obtaining dispersions of two-dimensional materials. It also offers the advantages of low cost and scalability [2]. The LPE process is initiated

DFT calculations of the structure and stability of copper clusters on MoS₂

• Cara-Lena Nies and
• Michael Nolan

Beilstein J. Nanotechnol. 2020, 11, 391–406, doi:10.3762/bjnano.11.30

• exfoliation. However, the scalability of CVD and ALD processes makes 2D materials grown via these methods more realistic for a wider range of applications [4]. Transition metal dichalcogenides (TMDs) are of particular interest as they exhibit a large variety of properties. TMDs such as MoS2 are intrinsic

Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• information, cost-efficiency, robustness of the reaction, scalability, high-throughput discrimination and the possibility for automatization with minimal hands-on operation. We will demonstrate in the following sections that the advancement of laboratory-based sensors for SNP discrimination benefits from the