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Search for "temozolomide" in Full Text gives 2 result(s) in Beilstein Journal of Nanotechnology.

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

  • Radmila Milenkovska,
  • Nikola Geskovski,
  • Dushko Shalabalija,
  • Ljubica Mihailova,
  • Petre Makreski,
  • Dushko Lukarski,
  • Igor Stojkovski,
  • Maja Simonoska Crcarevska and
  • Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

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  • , temozolomide (TMZ), a drug used for the treatment of anaplastic astrocytoma and glioblastoma multiforme (GBM), was incorporated into multiwalled carbon nanotubes (MWCNTs) and a MWCNTs–graphene (MWCNTs-G) hybrid compound, covalently functionalized with polyethylene glycol (PEG) 6000 and folic acid (FA), with an
  • nanostructures; cytotoxicity; glioblastoma multiforme; radiosensitizing properties; temozolomide; Introduction Carbon-based nanostructures (CNs) such as graphene and its derivatives, carbon nanotubes (CNTs), fullerenes, carbon quantum dots, carbon nanohorns and nanodiamonds (NDs), and their hybrids are becoming
  • , and photodynamic therapy. Cytotoxic drugs acting by preventing DNA replication and apoptosis via methylation of guanine-rich areas in DNA and by cross-linking guanine and cytosine in DNA strains are a standard in chemotherapy. Among them, the prodrug temozolomide (TMZ) with its active metabolite 5-(3
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Full Research Paper
Published 19 Feb 2025

Key for crossing the BBB with nanoparticles: the rational design

  • Sonia M. Lombardo,
  • Marc Schneider,
  • Akif E. Türeli and
  • Nazende Günday Türeli

Beilstein J. Nanotechnol. 2020, 11, 866–883, doi:10.3762/bjnano.11.72

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  • another study, arginine–glycine–aspartic acid peptide (RGD)-modified NLCs were used for the delivery of temozolomide (TMZ) and their efficacy was tested on a glioblastoma multiforme mouse model. The RGD-TMZ/NLCs displayed high antitumor efficacy in vivo, with an inhibition of the tumor four times higher
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Review
Published 04 Jun 2020
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