Formulation development, stability and anticancer efficacy of core-shell cyclodextrin nanocapsules for oral chemotherapy with camptothecin

Scholarly Works

• Rasjava, A. R.; Kurniawati, D.; Rizki, W. O. S.; Kurniati, N. F.; Hertadi, R. Development of inulin nanocarrier for effective oral delivery of insulin: synthesize, optimization, characterization, and biophysical study. Journal of Biomaterials Science, Polymer Edition 2024, 1–24. doi:10.1080/09205063.2024.2436297
• Srag El-Din, A. S.; Yehia, A.; Hamza, E.; A-Elgadir, T. M. E.; Abd El-Fattah, E. E. Selenium nanoparticle ameliorates LPS-induced acute lung injury in rats through inhibition of ferroptosis, inflammation, and HSPs. Journal of Drug Delivery Science and Technology 2024, 95, 105626. doi:10.1016/j.jddst.2024.105626
• Sarabia-Vallejo, Á.; Caja, M. D. M.; Olives, A. I.; Martín, M. A.; Menéndez, J. C. Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects. Pharmaceutics 2023, 15, 2345. doi:10.3390/pharmaceutics15092345
• Dehariya, D.; Eswar, K.; Tarafdar, A.; Balusamy, S.; Rengan, A. K. Recent advances of nanobubble-based systems in cancer therapeutics: A Review. Biomedical Engineering Advances 2023, 5, 100080. doi:10.1016/j.bea.2023.100080
• Yang, J.; Jia, L.; He, Z.; Wang, Y. Recent advances in SN-38 drug delivery system. International journal of pharmaceutics 2023, 637, 122886. doi:10.1016/j.ijpharm.2023.122886
• Ünal, S.; Varan, G.; Benito, J. M.; Aktaş, Y.; Bilensoy, E. Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors. Beilstein journal of organic chemistry 2023, 19, 139–157. doi:10.3762/bjoc.19.14
• Daşkın, D.; Erdoğar, N.; İskit, A. B.; Bilensoy, E. Oral docetaxel delivery with cationic polymeric core-shell nanocapsules: In vitro and in vivo evaluation. Journal of Drug Delivery Science and Technology 2023, 80, 104163. doi:10.1016/j.jddst.2023.104163
• Çetin, K.; Şarkaya, K.; Denizli, A. Clinical applications and future clinical trials of the drug delivery system. Nanotechnology for Drug Delivery and Pharmaceuticals; Elsevier, 2023; pp 259–294. doi:10.1016/b978-0-323-95325-2.00020-1
• Sachdeva, A.; Dhawan, D.; Jain, G. K.; Yerer, M. B.; Collignon, T. E.; Tewari, D.; Bishayee, A. Novel Strategies for the Bioavailability Augmentation and Efficacy Improvement of Natural Products in Oral Cancer. Cancers 2022, 15, 268. doi:10.3390/cancers15010268
• Ünal, S.; Doğan, O.; Aktaş, Y. Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics. Beilstein journal of nanotechnology 2022, 13, 1393–1407. doi:10.3762/bjnano.13.115
• Rao, Y.; Li, R.; Liu, S.; Meng, L.; Wu, Q.; Yuan, Q.; Liang, H.; Qin, M. Enhanced bioavailability and biosafety of cannabidiol nanomicelles for effective anti-inflammatory therapy. Particuology 2022, 69, 1–9. doi:10.1016/j.partic.2021.11.010
• Narayanan, G.; Shen, J.; Matai, I.; Sachdev, A.; Boy, R.; Tonelli, A. E. Cyclodextrin-based nanostructures. Progress in Materials Science 2022, 124, 100869. doi:10.1016/j.pmatsci.2021.100869
• Das, S. S.; Kar, S.; Singh, S.; Verma, P. R. P.; Hussain, A.; Beg, S. Chitosan-based systems for oral drug delivery applications. Chitosan in Drug Delivery; Elsevier, 2022; pp 23–53. doi:10.1016/b978-0-12-819336-5.00009-1
• Daşkın, D.; Erdoğar, N.; İskit, A. B.; Bilensoy, E. Oral Docetaxel Delivery with Cationic Polymeric Core-Shell Nanocapsules For Gastrointestinal Cancers: In Vitro and in Vivo Evaluation. SSRN Electronic Journal 2022. doi:10.2139/ssrn.4177749
• Pandya, M.; Chatterjee, B.; Ganti, S. Self-emulsifying Drug Delivery System for Oral Anticancer Therapy: Constraints and Recent Development. Current pharmaceutical design 2022, 28, 2538–2553. doi:10.2174/03666220606143443
• Ünal, S.; Öztürk, S. C.; Bilgiç, E.; Yanik, H.; Korkusuz, P.; Aktaş, Y.; Benito, J. M.; Esendagli, G.; Bilensoy, E. Therapeutic efficacy and gastrointestinal biodistribution of polycationic nanoparticles for oral camptothecin delivery in early and late-stage colorectal tumor-bearing animal model. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021, 169, 168–177. doi:10.1016/j.ejpb.2021.10.010
• González-Ruiz, V.; Cores, Á.; Martín-Cámara, O.; Orellana, K.; Cervera-Carrascón, V.; Michalska, P.; Olives, A. I.; León, R.; Martín, M. A.; Menéndez, J. C. Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation. Pharmaceutics 2021, 13, 1609. doi:10.3390/pharmaceutics13101609
• Su, C.; Ren, X.; Nie, F.; Li, T.; Lv, W.; Li, H.; Zhang, Y. Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives. RSC advances 2021, 11, 12915–12928. doi:10.1039/d0ra08727k
• Varan, G.; Varan, C.; Öztürk, S. C.; Benito, J. M.; Esendagli, G.; Bilensoy, E. Therapeutic Efficacy and Biodistribution of Paclitaxel-Bound Amphiphilic Cyclodextrin Nanoparticles: Analyses in 3D Tumor Culture and Tumor-Bearing Animals In Vivo. Nanomaterials (Basel, Switzerland) 2021, 11, 515. doi:10.3390/nano11020515
• Erdoğar, N.; Akkın, S.; Nielsen, T. T.; Özçelebi, E.; Erdogdu, B.; Nemutlu, E.; Iskit, A. B.; Bilensoy, E. Development of oral aprepitant-loaded chitosan–polyethylene glycol-coated cyclodextrin nanocapsules: formulation, characterization, and pharmacokinetic evaluation. Journal of Pharmaceutical Investigation 2021, 51, 297–310. doi:10.1007/s40005-020-00511-x

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