A general and atom-efficient continuous-flow approach to prepare amines, amides and imines via reactive N-chloramines

Scholarly Works

• Dean, J.; Buckler Reinoso, N.; Spiedo, F.; Romero Fernández, C.; Patel, B. Continuous Flow Optimisation of the Pudovik Reaction and Phospha-Brook Rearrangement Using DBN. Reactions 2024, 5, 812–822. doi:10.3390/reactions5040042
• Xu, J.; Zhang, Y.; Cai, Q.; Chen, L.; Sun, Y.; Liu, Q.; Gao, Y.; Chen, H. Green Late-Stage Functionalization of Tryptamines. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 30, e202401436. doi:10.1002/chem.202401436
• Constantinou, C. T.; Gkizis, P. L.; Lagopanagiotopoulou, O. T. G.; Skolia, E.; Nikitas, N. F.; Triandafillidi, I.; Kokotos, C. G. Photochemical Aminochlorination of Alkenes without the Use of an External Catalyst. Chemistry (Weinheim an der Bergstrasse, Germany) 2023, 29, e202301268. doi:10.1002/chem.202301268
• Gaspa, S.; Sciortino, G.; Porcheddu, A.; Dell'Osa, C.; Satta, G.; Azzena, U.; Pisano, L.; Carraro, M.; Sanna, D.; Garribba, E.; Maseras, F.; De Luca, L. Oxidovanadium(IV) sulfate catalyses light-driven C–N bond formation. Molecular Catalysis 2023, 541, 113054. doi:10.1016/j.mcat.2023.113054
• Polterauer, D.; Roberge, D. M.; Hanselmann, P.; Littich, R.; Hone, C. A.; Kappe, C. O. A continuous flow investigation of sulfonyl chloride synthesis using N-chloroamides: optimization, kinetics and mechanism. Reaction Chemistry & Engineering 2022, 7, 2582–2592. doi:10.1039/d2re00280a
• Govada, G. V.; Sabbasani, R. R. A new outlook in oxidative transformations and coupling reactions via in situ generation of organic chloramines. Applied Organometallic Chemistry 2022, 36. doi:10.1002/aoc.6518
• Li, B.; Yuan, J.; Ye, X.; Zhang, R.; Li, J.; Wang, Y.; Hu, J.; Dong, D. PIFA-Mediated Tandem Hofmann-Type Rearrangement and Cyclization Reaction of α-Acyl-β-aminoacrylamides: Access to Polysubstituted Oxazol-2(3H)-ones. The Journal of organic chemistry 2021, 86, 17944–17954. doi:10.1021/acs.joc.1c02276
• Steiner, A.; de Frutos, O.; Rincón, J. A.; Mateos, C.; Williams, J. D.; Kappe, C. O. N-Chloroamines as substrates for metal-free photochemical atom-transfer radical addition reactions in continuous flow. Reaction Chemistry & Engineering 2021, 6, 2434–2441. doi:10.1039/d1re00429h
• Morvan, J.; McBride, T.; Curbet, I.; Colombel‐Rouen, S.; Roisnel, T.; Crévisy, C.; Browne, D. L.; Mauduit, M. Continuous Flow Z‐Stereoselective Olefin Metathesis: Development and Applications in the Synthesis of Pheromones and Macrocyclic Odorant Molecules**. Angewandte Chemie 2021, 133, 19837–19842. doi:10.1002/ange.202106410
• Morvan, J.; McBride, T.; Curbet, I.; Colombel-Rouen, S.; Roisnel, T.; Crévisy, C.; Browne, D. L.; Mauduit, M. Continuous Flow Z-Stereoselective Olefin Metathesis: Development and Applications in the Synthesis of Pheromones and Macrocyclic Odorant Molecules**. Angewandte Chemie (International ed. in English) 2021, 60, 19685–19690. doi:10.1002/anie.202106410
• Engl, S.; Reiser, O. Catalyst-Free Visible-Light-Mediated Iodoamination of Olefins and Synthetic Applications. Organic letters 2021, 23, 5581–5586. doi:10.1021/acs.orglett.1c02035
• Victoria, G. G.; Reddy, S. R. Recent advances in the synthesis of organic chloramines and their insights into health care. New Journal of Chemistry 2021, 45, 8386–8408. doi:10.1039/d1nj01086g
• Taylor, C. J. Ph.D. Thesis, Dec 1, 2020.
• Liao, J.; Zhang, S.; Wang, Z.; Song, X.; Zhang, D.; Kumar, R.; Jin, J.; Ren, P.; You, H.; Chen, F.-E. Transition-metal catalyzed asymmetric reactions under continuous flow from 2015 to early 2020. Green Synthesis and Catalysis 2020, 1, 121–133. doi:10.1016/j.gresc.2020.08.001
• Danahy, K. E.; Styduhar, E. D.; Fodness, A. M.; Heckman, L. M.; Jamison, T. F. On-Demand Generation and Use in Continuous Synthesis of the Ambiphilic Nitrogen Source Chloramine. Organic letters 2020, 22, 8392–8395. doi:10.1021/acs.orglett.0c03021
• Niño, C. G. Ph.D. Thesis, Aug 10, 2020.
• Hafner, A.; Sedelmeier, J. Organometallic Chemistry in Industry; Wiley, 2020; pp 61–90. doi:10.1002/9783527819201.ch3
• Wang, J.; Yi, W.-J. Practical N-Hydroxyphthalimide-Mediated Oxidation of Sulfonamides to N-Sulfonylimines. Molecules (Basel, Switzerland) 2019, 24, 3771. doi:10.3390/molecules24203771

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