Steroid diversification by multicomponent reactions

Scholarly Works

• Larghi, E. L.; Bracca, A. B. J.; Simonetti, S. O.; Kaufman, T. S. Relevant Developments in the Use of Three-Component Reactions for the Total Synthesis of Natural Products. The last 15 Years. ChemistryOpen 2024, 13, e202300306. doi:10.1002/open.202300306
• Larghi, E. L.; Bracca, A. B. J.; Simonetti, S. O.; Kaufman, T. S. Recent developments in the total synthesis of natural products using the Ugi multicomponent reactions as the key strategy. Organic & biomolecular chemistry 2024, 22, 429–465. doi:10.1039/d3ob01837g
• Rodriguez-Lopez, F.; Rodríguez-García, E. G.; García-Gutiérrez, H. A.; Gámez-Montaño, R. Plant-Derived Triterpenoid Functionalization: Synthesis of α-Acyloxycarboxamides. In ECSOC 2023, MDPI, 2023; pp 102 ff. doi:10.3390/ecsoc-27-16061
• García-Santos, W. H.; Mayorquín-Torres, M. C.; Maldonado-Domínguez, M.; Medina-Campos, O. N.; Pedraza-Chaverri, J.; Iglesias-Arteaga, M. A. Mechanistic Insights on Pd-Catalyzed Three-Component Reactions of Alkynols, Methyl Orthoformate, and Salicylaldehyde Derivatives. Application to the Synthesis of Steroid Chroman Ketals and Spiroketals with Antioxidant Activity. The Journal of organic chemistry 2023, 88, 14860–14873. doi:10.1021/acs.joc.3c00857
• Hammouda, M. M.; Elattar, K. M.; Rashed, M. M.; Osman, A. M. A. Synthesis, biological activities, and future perspectives of steroidal monocyclic pyridines. RSC medicinal chemistry 2023, 14, 1934–1972. doi:10.1039/d3md00411b
• Alkubaisi, B. O.; Shahin, A. I.; Zenati, R. A.; Ravi, A.; Alchami, R.; Alkalla, M.; Khaled, R.; El-Gamal, M. I.; Al-Tel, T. H. Complexity-to-Diversity and Pseudo-Natural Product Strategies as Powerful Platforms for Deciphering Next-Generation Therapeutics. ChemMedChem 2023, 18, e202300117. doi:10.1002/cmdc.202300117
• Rodríguez-López, F.; García-Gutiérrez, H. A.; Gámez-Montaño, R. Synthesis of Bis-Amides Employing a Plant-Derived Triterpenoid as Component in the Ugi Reaction. In The 26th International Electronic Conference on Synthetic Organic Chemistry, MDPI, 2022; pp 37 ff. doi:10.3390/ecsoc-26-13560
• Molaei Yielzoleh, F.; Nikoofar, K. Metal-bio functionalized bismuthmagnetite [Fe3-x Bi x O4/SiO2@l-ArgEt3 +I-/Zn(ii)]: a novel bionanocomposite for the synthesis of 1,2,4,5-tetrahydro-2,4-dioxobenzo[b][1,4]diazepine malononitriles and malonamides at room temperature and under sonication. RSC advances 2022, 12, 10219–10236. doi:10.1039/d2ra00212d
• Yazdani, H.; Hooshmand, S. E.; Varma, R. S. Gold Nanoparticle-Catalyzed Multicomponent Reactions. ACS Sustainable Chemistry & Engineering 2021, 9, 16556–16569. doi:10.1021/acssuschemeng.1c04361
• Rodríguez-López, F.; García-Gutiérrez, H. A.; Gámez-Montaño, R. Synthesis of Triterpenoid-Derived α-Acyloxycarboxamides via Passerini Reaction. In The 25th International Electronic Conference on Synthetic Organic Chemistry, MDPI, 2021; pp 51 ff. doi:10.3390/ecsoc-25-11785
• Sepahvand, H.; Heravi, M. M.; Saber, M.; Hooshmand, S. E. Techniques and support materials for enzyme immobilization using Ugi multicomponent reaction: an overview. Journal of the Iranian Chemical Society 2021, 19, 2115–2130. doi:10.1007/s13738-021-02449-9
• Irani, M.; Ranjbar-Karimi, R.; Poorfreidoni, A.; Mehrabi, H. The reactivity of isocyanides with pentafluoropyridine. Monatshefte für Chemie - Chemical Monthly 2021, 152, 1369–1375. doi:10.1007/s00706-021-02856-x
• Iqbal, A.; Siddiqui, T. A review on synthesis and biological activities of d-ring modified pregnenolone. Steroids 2021, 170, 108827. doi:10.1016/j.steroids.2021.108827
• Sommer, F.; Kappe, C. O.; Cantillo, D. Electrochemically Enabled One-Pot Multistep Synthesis of C19 Androgen Steroids. Chemistry (Weinheim an der Bergstrasse, Germany) 2021, 27, 6044–6049. doi:10.1002/chem.202100446
• Wang, X.; Bao, H.; Bau, T. Investigation of the possible mechanism of two kinds of sterols extracted from Leucocalocybe mongolica in inducing HepG2 cell apoptosis and exerting anti-tumor effects in H22 tumor-bearing mice. Steroids 2020, 163, 108692. doi:10.1016/j.steroids.2020.108692
• Townsend, D.; Shankland, K.; Weymouth-Wilson, A. C.; Komsta, Z.; Timothy, E.; Cobb, A. J. A. Synthesis of an intriguing steroidal constitutional isomer. Tetrahedron Letters 2020, 61, 151942. doi:10.1016/j.tetlet.2020.151942
• Singla, P.; Salunke, D. B. Recent advances in steroid amino acid conjugates: Old scaffolds with new dimensions. European journal of medicinal chemistry 2019, 187, 111909. doi:10.1016/j.ejmech.2019.111909

Explore citations to this article at