Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties

Scholarly Works

• Nair, V. A.; Radhakrishna, V. Y.; Khatik, G. L. 1,3-Dipolar Cycloaddition Reaction of Nitrile Oxide to Thiocyanates: An Efficient and Eco-Friendly Synthesis of N-Aryl-2-((3-aryl-1,2,4-oxadiazol-5-yl)thio)acetamides. Synthesis 2024, 56, 3173–3180. doi:10.1055/s-0043-1775390
• Singh, S.; Lakhia, R.; Yadav, S.; Devi, P.; Yadav, K.; Chaudhri, V.; Pundeer, R. Advancements in the Synthesis of Triazolopyrimidines. Current Organic Chemistry 2024, 28, 1567–1578. doi:10.2174/0113852728313437240607095009
• Kucukoglu, K.; Faydali, N.; Bul, D.; Nadaroglu, H.; Sever, B.; Altıntop, M. D.; Ozturk, B.; Guzel, I. Synthesis, in silico and in vitro evaluation of new 3,5-disubstituted-1,2,4-oxadiazole derivatives as carbonic anhydrase inhibitors and cytotoxic agents. Journal of Molecular Structure 2023, 1276, 134699. doi:10.1016/j.molstruc.2022.134699
• Chilaka, S. K.; Chellu, R. K.; Soda, A. K.; Kurva, S.; Nanubolu, J. B.; Madabhushi, S. Base‐Catalyzed Domino Reaction Between Aldoxime and N‐Chlorosuccinimide in Alcohol: One‐Pot Synthesis of Alkyl 3‐(3‐Aryl‐1,2,4‐oxadiazol‐5‐yl)propanoates. Advanced Synthesis & Catalysis 2022, 364, 2944–2950. doi:10.1002/adsc.202200265
• Desai, K. R.; Patel, B. R. Various Synthetic Strategies and Therapeutic Potential of Thiadiazole, Oxadiazole, Isoxazole and Isothiazole Derivatives. N-Heterocycles; Springer Nature Singapore, 2022; pp 221–274. doi:10.1007/978-981-19-0832-3_6
• Zhang, C. Application of Aromatic Substituted 2,2,2-Trifluoro Diazoethanes in Organic Reactions. Current Organic Chemistry 2022, 26, 639–650. doi:10.2174/1385272826666220516113815
• Roy, J. The synthesis and applications of TiO2 nanoparticles derived from phytochemical sources. Journal of Industrial and Engineering Chemistry 2022, 106, 1–19. doi:10.1016/j.jiec.2021.10.024
• Wolf, L.; Mayer, J. C.; Quoos, N.; Sauer, A. C.; Schwab, R. S.; Rodrigues, O. E. D.; Dornelles, L. One-pot synthesis of 1,2,4-oxadiazoles from chalcogen amino acid derivatives under microwave irradiation. Tetrahedron 2021, 91, 132222. doi:10.1016/j.tet.2021.132222
• Farooq, M. U.; Naz, M. Y.; Hussain, M.; Shukrullah, S.; Makhlouf, M. M. Smart Therapeutic Strategy of pH-Responsive Gold Nanoparticles for Combating Multidrug Resistance. Particle & Particle Systems Characterization 2021, 38, 2100073. doi:10.1002/ppsc.202100073
• Kapoor, G.; Bhutani, R.; Pathak, D. P.; Chauhan, G.; Kant, R.; Grover, P.; Nagarajan, K.; Siddiqui, S. A. Current Advancement in the Oxadiazole-Based Scaffolds as Anticancer Agents. Polycyclic Aromatic Compounds 2021, 1–33.
• Kapoor, G.; Bhutani, R.; Pathak, D. P.; Chauhan, G.; Kant, R.; Grover, P.; Nagarajan, K.; Siddiqui, S. A. Current Advancement in the Oxadiazole-Based Scaffolds as Anticancer Agents. Polycyclic Aromatic Compounds 2021, 42, 4183–4215. doi:10.1080/10406638.2021.1886123
• Avila, C.; Angulo-Preckler, C. Bioactive Compounds from Marine Heterobranchs. Marine drugs 2020, 18, 657. doi:10.3390/md18120657
• Woliński, P.; Kącka-Zych, A.; Demchuk, O. M.; Łapczuk-Krygier, A.; Miroslaw, B.; Jasiński, R. Clean and molecularly programmable protocol for preparation of bis-heterobiarylic systems via a domino pseudocyclic reaction as a valuable alternative for TM-catalyzed cross-couplings. Journal of Cleaner Production 2020, 275, 122086. doi:10.1016/j.jclepro.2020.122086
• Baikov, S. V.; Trukhanova, Y. A.; Tarasenko, M. V.; Kinzhalov, M. A. Synthesis and Study of the Structure of Palladium(II) AcyclicDiaminocarbene Complexes Containing a 1,2,4-Oxadiazole Moiety. Russian Journal of General Chemistry 2020, 90, 1892–1900. doi:10.1134/s1070363220100126
• Penjarla, S.; Sabui, S. K.; Reddy, D. S.; Banerjee, S.; Reddy, P. Y.; Penta, S.; Sanghvi, Y. S. An efficient synthesis tetrazole and oxadiazole analogues of novel 2′-deoxy-C-nucleosides and their antitumor activity. Bioorganic & medicinal chemistry letters 2020, 30, 127612. doi:10.1016/j.bmcl.2020.127612
• Ceramella, J.; Mariconda, A.; Rosano, C.; Iacopetta, D.; Caruso, A.; Longo, P.; Sinicropi, M. S.; Saturnino, C. α-ω Alkenyl-bis-S-Guanidine Thiourea Dihydrobromide Affects HeLa Cell Growth Hampering Tubulin Polymerization. ChemMedChem 2020, 15, 2306–2316. doi:10.1002/cmdc.202000544
• Biernacki, K.; Daśko, M.; Ciupak, O.; Kubiński, K.; Rachon, J.; Demkowicz, S. Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery. Pharmaceuticals (Basel, Switzerland) 2020, 13, 111. doi:10.3390/ph13060111
• Özer, B.; Dürüst, Y. Synthesis of Some Azamacrocycles Bearing 1,2,4-Oxadiazole and 1,2,3-Triazole Moieties. Russian Journal of Organic Chemistry 2020, 56, 698–705. doi:10.1134/s1070428020040193
• El-Mekabaty, A.; Etman, H. A.; Mosbah, A.; Fadda, A. A. Synthesis, In Vitro Cytotoxicity and Bleomycin-Dependent DNA Damage Evaluation of Some Heterocyclic-Fused Pyrimidinone Derivatives. ChemistrySelect 2020, 5, 4856–4861. doi:10.1002/slct.202001006
• Bumbăcilă, B.; Putz, M. V. Neurotoxicity of Pesticides: The Roadmap for the Cubic Mode of Action. Current medicinal chemistry 2020, 27, 54–77. doi:10.2174/0929867326666190704142354

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