Natural products in synthesis and biosynthesis
Technische Universität Braunschweig
See also the Thematic Series:
Natural products in synthesis and biosynthesis II
See videos about natural products at Beilstein TV.
Natural products in synthesis and biosynthesis
- Jeroen S. Dickschat
Beilstein J. Org. Chem. 2013, 9, 1897–1898, doi:10.3762/bjoc.9.223
Total synthesis of ochnaflavone
- Monica M. Ndoile and
- Fanie R. van Heerden
Beilstein J. Org. Chem. 2013, 9, 1346–1351, doi:10.3762/bjoc.9.152
Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues
- Xu-Wen Li,
- Jennifer Herrmann,
- Yi Zang,
- Philippe Grellier,
- Soizic Prado,
- Rolf Müller and
- Bastien Nay
Beilstein J. Org. Chem. 2013, 9, 1551–1558, doi:10.3762/bjoc.9.176
New tridecapeptides of the theonellapeptolide family from the Indonesian sponge Theonella swinhoei
- Annamaria Sinisi,
- Barbara Calcinai,
- Carlo Cerrano,
- Henny A. Dien,
- Angela Zampella,
- Claudio D’Amore,
- Barbara Renga,
- Stefano Fiorucci and
- Orazio Taglialatela-Scafati
Beilstein J. Org. Chem. 2013, 9, 1643–1651, doi:10.3762/bjoc.9.188
Synthesis of the reported structure of piperazirum using a nitro-Mannich reaction as the key stereochemical determining step
- James C. Anderson,
- Andreas S. Kalogirou,
- Michael J. Porter and
- Graham J. Tizzard
Beilstein J. Org. Chem. 2013, 9, 1737–1744, doi:10.3762/bjoc.9.200
Activation of cryptic metabolite production through gene disruption: Dimethyl furan-2,4-dicarboxylate produced by Streptomyces sahachiroi
- Dinesh Simkhada,
- Huitu Zhang,
- Shogo Mori,
- Howard Williams and
- Coran M. H. Watanabe
Beilstein J. Org. Chem. 2013, 9, 1768–1773, doi:10.3762/bjoc.9.205
Synthesis and antibacterial activity of monocyclic 3-carboxamide tetramic acids
- Yong-Chul Jeong and
- Mark G. Moloney
Beilstein J. Org. Chem. 2013, 9, 1899–1906, doi:10.3762/bjoc.9.224
Stereoselective synthesis of the C79–C97 fragment of symbiodinolide
- Hiroyoshi Takamura,
- Takayuki Fujiwara,
- Isao Kadota and
- Daisuke Uemura
Beilstein J. Org. Chem. 2013, 9, 1931–1935, doi:10.3762/bjoc.9.228
A concise enantioselective synthesis of the guaiane sesquiterpene (−)-oxyphyllol
- Martin Zahel and
- Peter Metz
Beilstein J. Org. Chem. 2013, 9, 2028–2032, doi:10.3762/bjoc.9.239
The chemistry of isoindole natural products
- Klaus Speck and
- Thomas Magauer
Beilstein J. Org. Chem. 2013, 9, 2048–2078, doi:10.3762/bjoc.9.243
Flexible synthesis of anthracycline aglycone mimics via domino carbopalladation reactions
- Markus Leibeling and
- Daniel B. Werz
Beilstein J. Org. Chem. 2013, 9, 2194–2201, doi:10.3762/bjoc.9.258
Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties
- Catalin V. Maftei,
- Elena Fodor,
- Peter G. Jones,
- M. Heiko Franz,
- Gerhard Kelter,
- Heiner Fiebig and
- Ion Neda
Beilstein J. Org. Chem. 2013, 9, 2202–2215, doi:10.3762/bjoc.9.259
Elucidation of the regio- and chemoselectivity of enzymatic allylic oxidations with Pleurotus sapidus – conversion of selected spirocyclic terpenoids and computational analysis
- Verena Weidmann,
- Mathias Schaffrath,
- Holger Zorn,
- Julia Rehbein and
- Wolfgang Maison
Beilstein J. Org. Chem. 2013, 9, 2233–2241, doi:10.3762/bjoc.9.262
Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling
- Johann Moschner,
- Anna Chentsova,
- Nicole Eilert,
- Irene Rovardi,
- Philipp Heretsch and
- Athanassios Giannis
Beilstein J. Org. Chem. 2013, 9, 2328–2335, doi:10.3762/bjoc.9.267
Towards stereochemical control: A short formal enantioselective total synthesis of pumiliotoxins 251D and 237A
- Jie Zhang,
- Hong-Kui Zhang and
- Pei-Qiang Huang
Beilstein J. Org. Chem. 2013, 9, 2358–2366, doi:10.3762/bjoc.9.271
A protecting group-free synthesis of the Colorado potato beetle pheromone
- Zhongtao Wu,
- Manuel Jäger,
- Jeffrey Buter and
- Adriaan J. Minnaard
Beilstein J. Org. Chem. 2013, 9, 2374–2377, doi:10.3762/bjoc.9.273
Biosynthesis of rare hexoses using microorganisms and related enzymes
- Zijie Li,
- Yahui Gao,
- Hideki Nakanishi,
- Xiaodong Gao and
- Li Cai
Beilstein J. Org. Chem. 2013, 9, 2434–2445, doi:10.3762/bjoc.9.281
Synthesis of the spiroketal core of integramycin
- Evgeny. V. Prusov
Beilstein J. Org. Chem. 2013, 9, 2446–2450, doi:10.3762/bjoc.9.282
Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C2-symmetric building block: a strategy for the synthesis of decanolide natural products
- Bernd Schmidt and
- Oliver Kunz
Beilstein J. Org. Chem. 2013, 9, 2544–2555, doi:10.3762/bjoc.9.289
The regulation and biosynthesis of antimycins
- Ryan F. Seipke and
- Matthew I. Hutchings
Beilstein J. Org. Chem. 2013, 9, 2556–2563, doi:10.3762/bjoc.9.290
Stereodivergent synthesis of jaspine B and its isomers using a carbohydrate-derived alkoxyallene as C3-building block
- Volker M. Schmiedel,
- Stefano Stefani and
- Hans-Ulrich Reissig
Beilstein J. Org. Chem. 2013, 9, 2564–2569, doi:10.3762/bjoc.9.291
The myxocoumarins A and B from Stigmatella aurantiaca strain MYX-030
- Tobias A. M. Gulder,
- Snežana Neff,
- Traugott Schüz,
- Tammo Winkler,
- René Gees and
- Bettina Böhlendorf
Beilstein J. Org. Chem. 2013, 9, 2579–2585, doi:10.3762/bjoc.9.293
Garner’s aldehyde as a versatile intermediate in the synthesis of enantiopure natural products
- Mikko Passiniemi and
- Ari M.P. Koskinen
Beilstein J. Org. Chem. 2013, 9, 2641–2659, doi:10.3762/bjoc.9.300
Halogenated volatiles from the fungus Geniculosporium and the actinomycete Streptomyces chartreusis
- Tao Wang,
- Patrick Rabe,
- Christian A. Citron and
- Jeroen S. Dickschat
Beilstein J. Org. Chem. 2013, 9, 2767–2777, doi:10.3762/bjoc.9.311
[2H26]-1-epi-Cubenol, a completely deuterated natural product from Streptomyces griseus
- Christian A. Citron and
- Jeroen S. Dickschat
Beilstein J. Org. Chem. 2013, 9, 2841–2845, doi:10.3762/bjoc.9.319
SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expression
- Silke Felix,
- Louis P. Sandjo,
- Till Opatz and
- Gerhard Erkel
Beilstein J. Org. Chem. 2013, 9, 2866–2876, doi:10.3762/bjoc.9.323
Studies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity
- Thomas A. Munro,
- Wei Xu,
- Douglas M. Ho,
- Lee-Yuan Liu-Chen and
- Bruce M. Cohen
Beilstein J. Org. Chem. 2013, 9, 2916–2924, doi:10.3762/bjoc.9.328
Synthesis and determination of the absolute configuration of (−)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoni
- I. Wayan Mudianta,
- Victoria L. Challinor,
- Anne E. Winters,
- Karen L. Cheney,
- James J. De Voss and
- Mary J. Garson
Beilstein J. Org. Chem. 2013, 9, 2925–2933, doi:10.3762/bjoc.9.329
Synthesis of novel derivatives of 5-hydroxymethylcytosine and 5-formylcytosine as tools for epigenetics
- Anna Chentsova,
- Era Kapourani and
- Athanassios Giannis
Beilstein J. Org. Chem. 2014, 10, 7–11, doi:10.3762/bjoc.10.2
Total synthesis of (+)-grandiamide D, dasyclamide and gigantamide A from a Baylis–Hillman adduct: A unified biomimetic approach
- Andivelu Ilangovan and
- Shanmugasundar Saravanakumar
Beilstein J. Org. Chem. 2014, 10, 127–133, doi:10.3762/bjoc.10.9
Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1–DNA-complex formation
- Midori A. Arai,
- Kyoko Uchida,
- Samir K. Sadhu,
- Firoj Ahmed and
- Masami Ishibashi
Beilstein J. Org. Chem. 2014, 10, 134–140, doi:10.3762/bjoc.10.10
Recent applications of the divinylcyclopropane–cycloheptadiene rearrangement in organic synthesis
- Sebastian Krüger and
- Tanja Gaich
Beilstein J. Org. Chem. 2014, 10, 163–193, doi:10.3762/bjoc.10.14
Synthesis of the B-seco limonoid core scaffold
- Hanna Bruss,
- Hannah Schuster,
- Rémi Martinez,
- Markus Kaiser,
- Andrey P. Antonchick and
- Herbert Waldmann
Beilstein J. Org. Chem. 2014, 10, 194–208, doi:10.3762/bjoc.10.15
Tanzawaic acids I–L: Four new polyketides from Penicillium sp. IBWF104-06
- Louis P. Sandjo,
- Eckhard Thines,
- Till Opatz and
- Anja Schüffler
Beilstein J. Org. Chem. 2014, 10, 251–258, doi:10.3762/bjoc.10.20
Decandrinin, an unprecedented C9-spiro-fused 7,8-seco-ent-abietane from the Godavari mangrove Ceriops decandra
- Hui Wang,
- Min-Yi Li,
- Félix Zongwe Katele,
- Tirumani Satyanandamurty,
- Jun Wu and
- Gerhard Bringmann
Beilstein J. Org. Chem. 2014, 10, 276–281, doi:10.3762/bjoc.10.23
Total synthesis and cytotoxicity of the marine natural product malevamide D and a photoreactive analog
- Werner Telle,
- Gerhard Kelter,
- Heinz-Herbert Fiebig,
- Peter G. Jones and
- Thomas Lindel
Beilstein J. Org. Chem. 2014, 10, 316–322, doi:10.3762/bjoc.10.29
Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding
- Wolfgang Hüttel,
- Jonathan B. Spencer and
- Peter F. Leadlay
Beilstein J. Org. Chem. 2014, 10, 361–368, doi:10.3762/bjoc.10.34
Concise, stereodivergent and highly stereoselective synthesis of cis- and trans-2-substituted 3-hydroxypiperidines – development of a phosphite-driven cyclodehydration
- Peter H. Huy,
- Julia C. Westphal and
- Ari M. P. Koskinen
Beilstein J. Org. Chem. 2014, 10, 369–383, doi:10.3762/bjoc.10.35
Preparation of new alkyne-modified ansamitocins by mutasynthesis
- Kirsten Harmrolfs,
- Lena Mancuso,
- Binia Drung,
- Florenz Sasse and
- Andreas Kirschning
Beilstein J. Org. Chem. 2014, 10, 535–543, doi:10.3762/bjoc.10.49
New sesquiterpene hydroquinones from the Caribbean sponge Aka coralliphagum
- Qun Göthel and
- Matthias Köck
Beilstein J. Org. Chem. 2014, 10, 613–621, doi:10.3762/bjoc.10.52
Synthesis of complex intermediates for the study of a dehydratase from borrelidin biosynthesis
- Frank Hahn,
- Nadine Kandziora,
- Steffen Friedrich and
- Peter F. Leadlay
Beilstein J. Org. Chem. 2014, 10, 634–640, doi:10.3762/bjoc.10.55
Synthesis of (2S,3R)-3-amino-2-hydroxydecanoic acid and its enantiomer: a non-proteinogenic amino acid segment of the linear pentapeptide microginin
- Rajendra S. Rohokale and
- Dilip D. Dhavale
Beilstein J. Org. Chem. 2014, 10, 667–671, doi:10.3762/bjoc.10.59
Asymmetric total synthesis of a putative sex pheromone component from the parasitoid wasp Trichogramma turkestanica
- Danny Geerdink,
- Jeffrey Buter,
- Teris A. van Beek and
- Adriaan J. Minnaard
Beilstein J. Org. Chem. 2014, 10, 761–766, doi:10.3762/bjoc.10.71
Structure elucidation of female-specific volatiles released by the parasitoid wasp Trichogramma turkestanica (Hymenoptera: Trichogrammatidae)
- Armin Tröger,
- Teris A. van Beek,
- Martinus E. Huigens,
- Isabel M. M. S. Silva,
- Maarten A. Posthumus and
- Wittko Francke
Beilstein J. Org. Chem. 2014, 10, 767–773, doi:10.3762/bjoc.10.72
Amino acid motifs in natural products: synthesis of O-acylated derivatives of (2S,3S)-3-hydroxyleucine
- Oliver Ries,
- Martin Büschleb,
- Markus Granitzka,
- Dietmar Stalke and
- Christian Ducho
Beilstein J. Org. Chem. 2014, 10, 1135–1142, doi:10.3762/bjoc.10.113
Heronapyrrole D: A case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery
- Jens Schmidt,
- Zeinab Khalil,
- Robert J. Capon and
- Christian B. W. Stark
Beilstein J. Org. Chem. 2014, 10, 1228–1232, doi:10.3762/bjoc.10.121
Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from Thermobifida fusca YX
- Anna M. Bogazkaya,
- Clemens J. von Bühler,
- Sebastian Kriening,
- Alexandrine Busch,
- Alexander Seifert,
- Jürgen Pleiss,
- Sabine Laschat and
- Vlada B. Urlacher
Beilstein J. Org. Chem. 2014, 10, 1347–1353, doi:10.3762/bjoc.10.137
Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5
- Ulrike Groenhagen,
- Michael Maczka,
- Jeroen S. Dickschat and
- Stefan Schulz
Beilstein J. Org. Chem. 2014, 10, 1421–1432, doi:10.3762/bjoc.10.146
C–H-Functionalization logic guides the synthesis of a carbacyclopamine analog
- Sebastian Rabe,
- Johann Moschner,
- Marina Bantzi,
- Philipp Heretsch and
- Athanassios Giannis
Beilstein J. Org. Chem. 2014, 10, 1564–1569, doi:10.3762/bjoc.10.161
Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid
- Patrick Rabe,
- Tim A. Klapschinski,
- Nelson L. Brock,
- Christian A. Citron,
- Paul D’Alvise,
- Lone Gram and
- Jeroen S. Dickschat
Beilstein J. Org. Chem. 2014, 10, 1796–1801, doi:10.3762/bjoc.10.188
Sacrolide A, a new antimicrobial and cytotoxic oxylipin macrolide from the edible cyanobacterium Aphanothece sacrum
- Naoya Oku,
- Miyako Matsumoto,
- Kohsuke Yonejima,
- Keijiroh Tansei and
- Yasuhiro Igarashi
Beilstein J. Org. Chem. 2014, 10, 1808–1816, doi:10.3762/bjoc.10.190
