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Beilstein J. Org. Chem. 2024, 20, 1462–1467, doi:10.3762/bjoc.20.129
Graphical Abstract
Figure 1: Organofluorine derived drugs.
Scheme 1: Oxyfluorination of benzonorbornadien (1a) with Selectfluor and alcohols. All reactions were carried...
Scheme 2: Oxyfluorination of (+)-camphene (1b) with selectfluor and alcohols. All reactions were carried out ...
Scheme 3: Scale-up experiments. Reaction conditions: (+)-Camphene (1b) (1.0 g, 7.34 mmol), selectfluor (3.12 ...
Scheme 4: Proposed mechanism for fluoroalkoxylation of (+)-camphene by Wagner–Meerwein rearrangement.