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Beilstein J. Org. Chem. 2025, 21, 533–540, doi:10.3762/bjoc.21.41
Graphical Abstract
Figure 1: Biologically active compounds featuring a trifluoromethyl carbinol motif.
Figure 2: Nucleophilic sites of 5-aminopyrazoles and 4-alkenyl-5-aminopyrazoles. Stereoselective synthesis of...
Scheme 1: Synthesis of the starting materials 3.
Scheme 2: Scope of the reaction. Reaction conditions A: 3 (0.2 mmol) and 4 (0.6 mmol) in 2 mL of toluene at 7...
Scheme 3: Plausible mechanism and X-ray structure of compound 5aca.