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Beilstein J. Org. Chem. 2025, 21, 749–754, doi:10.3762/bjoc.21.58
Graphical Abstract
Scheme 1: Synthetic strategies for the construction of spirotetrahydroquinoline (STHQ) scaffolds.
Scheme 2: Substrate scope. General reaction conditions: aniline 1 (0.2 mmol), 2 (0.4 mmol), and Cu(TFA)2 (0.0...
Scheme 3: Scale-up reaction.a
Scheme 4: Proposed mechanism.