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Beilstein J. Org. Chem. 2024, 20, 2461–2468, doi:10.3762/bjoc.20.210
Graphical Abstract
Figure 1: A) Photoredox amidocyclization reaction. B) The strongly oxidizing Fukuzumi catalyst (I) used in th...
Figure 2: A) Access of clavam derivatives by intramolecular photoredox reaction of alkenes. B) Clavulanic aci...
Scheme 1: Preparation of alkenyl β-lactam derivatives for the intramolecular photoredox reaction.
Scheme 2: Photoredox-catalyzed intramolecular N-alkylation reactions of various β-lactams. The trans/cis dr w...
Scheme 3: Synthesis of the model substrate 14 and its photoredox-catalyzed intramolecular N-alkylation reacti...
Figure 3: Tentative mechanism for the photo-cyclization reaction.
Beilstein J. Org. Chem. 2023, 19, 1243–1250, doi:10.3762/bjoc.19.92
Scheme 1: Original triple organocatalytic cascade reaction developed by Enders.
Figure 1: Approaches based on the original Enders cascade reaction to access trisubstituted cyclohexene carba...
Scheme 2: Acetaldehyde dimethyl acetal (6) as an acetaldehyde surrogate to effect a triple organocatalytic ca...
Figure 2: Scope of the cascade reaction using 6 as an acetaldehyde equivalent. Reaction conditions: 3 (0.5 mm...