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1 article(s) from Molander, Gary A

Photocatalyzed elaboration of antibody-based bioconjugates

Marine Le Stum,
Eugénie Romero and
Gary A. Molander

Beilstein J. Org. Chem. 2025, 21, 616–629, doi:10.3762/bjoc.21.49

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Graphical Abstract

Figure 1: Representation of an antibody–drug conjugate. The antibody shown in this figure is from https://www...

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Figure 2: a. Photoredox catalytic cycles; b. absorption spectrum of photosensitizers. Therapeutic window indi...

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Figure 3: Graph representing the average number of publications focusing on photoredox chemistry applied to p...

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Figure 4: Schematic procedure developed by Sato et al. on histidine photoinduced modification. The antibody s...

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Figure 5: Schematic procedure of the divergent method developed by Sato et al. on histidine/tyrosine photoind...

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Figure 6: Schematic procedure developed by Bräse et al. on photoinduced disulfide rebridging method.

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Figure 7: Schematic procedure developed by Lang et al. on a photoinduced dual nickel photoredox-catalyzed app...

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Figure 8: Schematic of the procedure developed by Chang et al. on photoinduced high affinity IgG Fc-binding s...

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Figure 9: Potential advantages of photoredox chemistry for bioconjugation applied to antibodies. The antibody...

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Figure 10: Representation of the photoinduced control of the DAR. The antibody shown in this figure is from ht...

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Figure 11: Representation of a photoinduced control of multi-payloads ADC strategy. The antibody shown in this...

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Published 18 Mar 2025

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