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Beilstein J. Org. Chem. 2024, 20, 3198–3204, doi:10.3762/bjoc.20.265
Graphical Abstract
Scheme 1: The CuAAC reaction and installation of functional groups for product diversification.
Scheme 2: Scope of germanyl acetylene CuAAC. Alkyne (1.0 equiv), azide (1.1 equiv), CuSO4·5H2O (5.0 mol %), N...
Scheme 3: (a) Application of Ge-alkyne CuAAC to functional molecules. (b) Functionalisation of germylated tri...
Beilstein J. Org. Chem. 2016, 12, 2005–2011, doi:10.3762/bjoc.12.187
Scheme 1: The Sonogashira reaction.
Figure 1: Cyrene vs. DMF – selected physical properties [31,32].
Figure 2: Aldol products 4a and 4b and single crystal X-ray structure of 4b.
Scheme 2: Cyrene-based Sonogashira cross-coupling: Substrate scope. Isolated yields. aYield using DMF as solv...
Scheme 3: Cacchi-type annulation of o-amino/hydroxy iodoarenes. Isolated yields. aYield using DMF as solvent.