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Beilstein J. Org. Chem. 2024, 20, 1476–1485, doi:10.3762/bjoc.20.131
Graphical Abstract
Figure 1: (a) Domain compositions and the products of α-, β-, γ- and δ-modules in cis-AT PKSs. (b) Stereocont...
Figure 2: (a) Classification and distribution of the collected KR sequences according to host taxonomy, modul...
Figure 3: (a) The position of fingerprint motifs in the KR structure (AmpKR2, A1-type, PDB ID 5XWV) [29]. Fingerp...
Figure 4: Sequence logo comparation of γ- and δ-module KRC based on the classification of their products. Top...
Figure 5: Summary of the updated fingerprints sorted by the taxonomic origin and the module type. Percentage ...
Beilstein J. Org. Chem. 2022, 18, 1107–1115, doi:10.3762/bjoc.18.113
Figure 1: Structures of cattleyaisoflavones A (1), B (2), C (3), and daidzein (4).
Figure 2: a) The culture in ISP-2 liquid did not produce 1–3, while feeding with 4 restored the production (a...
Figure 3: CYP158C1 dimerizes 4 to form dimers 2 and 5 in vitro (analytical method B, 254 nm). Control conditi...
Scheme 1: a) Compatible and b) incompatible substrates of CYP158C1. Products were identified using analytical...
Scheme 2: Proposed mechanism of CYP158C1-mediated dimerization of isoflavones.