Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues

• Lucie Brulikova and
• Jan Hlavac

Beilstein J. Org. Chem. 2011, 7, 678–698, doi:10.3762/bjoc.7.80

• of 3',5'-dihydroxyl groups with the TBDMS group followed by a Pd-catalyzed coupling reaction with vinyl acetate to give the protected 5-vinyluridine 129 in 68% yield. Oxidation with OsO4 with subsequent acetylation with acetic anhydride in pyridine gave nucleoside 131. The target phosphoramidite 134

Synthesis of chiral mono(N-heterocyclic carbene) palladium and gold complexes with a 1,1'-biphenyl scaffold and their applications in catalysis

• Lian-jun Liu,
• Feijun Wang,
• Wenfeng Wang,
• Mei-xin Zhao and
• Min Shi

Beilstein J. Org. Chem. 2011, 7, 555–564, doi:10.3762/bjoc.7.64

• coupling reactions and a Au-catalyzed asymmetric reaction, respectively. Suzuki–Miyaura and Heck–Mizoroki coupling reactions catalyzed by NHC–Pd(II) complex The Pd-catalyzed coupling reaction is one of the most powerful methods for the formation of carbon–carbon bonds in organic synthesis [60][61][62][63

• reported NHC–Au complexes [57][58][59]. The NHC–metal complex [(NHC)Pd(allyl)I] complex 7 and NHC–Au(I) complex (S)-6a, are air and moisture stable both in the solid state and in solution, and can be used as catalysts. Therefore, the catalytic activities of these complexes were investigated in Pd-catalyzed

Conjugated polymers containing diketopyrrolopyrrole units in the main chain

• Bernd Tieke,
• A. Raman Rabindranath,
• Kai Zhang and
• Yu Zhu

Beilstein J. Org. Chem. 2010, 6, 830–845, doi:10.3762/bjoc.6.92

• monomer as well as conventional Pd-catalyzed coupling of M-1 and the 3,6-diphenyl(4,4´-bis(pinacolato)boron ester) derivative of DPP. The polymer exhibits a bordeaux-red colour in solution with absorption maxima of about 525 nm, and a purple luminescence with a maximum around 630 nm with a Stokes-shift of

• spectroelectrochemical plots of P-25 and P-26 as thin films on ITO glass. Scan rate: 100 mVs−1; potential vs. ferrocene (from [50]). Synthesis of DPP monomers. Pd-catalyzed coupling reactions for preparation of DPP-containing polymers. Thiophenyl-DPP-based polymers. List of diphenylDPP-based polymers prepared upon

Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: A new route to pyrano[4,3-c]pyrazol-4(1H)-ones

• Dhilli Rao Gorja,
• Venkateswara Rao Batchu,
• Ashok Ettam and
• Manojit Pal

Beilstein J. Org. Chem. 2009, 5, No. 64, doi:10.3762/bjoc.5.64

• conditions on the Pd-catalyzed coupling of 5-iodo-1-methyl-1H-pyrazole-4-carboxylic acid (1) with 1-hexyne (2a).a Pd/C-mediated synthesis of 6-substituted pyrano[4,3-c]pyrazol-4(1H)-onesa (3). Supporting Information Supporting Information File 84: General procedure for the preparation of 3 and spectral data

Shape- persistent macrocycle with intraannular alkyl groups: some structural limits of discotic liquid crystals with an inverted structure

• Sigurd Höger,
• Jill Weber,
• Andreas Leppert and
• Volker Enkelmann

Beilstein J. Org. Chem. 2008, 4, No. 1, doi:10.1186/1860-5397-4-1

• compared to macrocycle 1. 3,5-Diiodo-4-methylbenzene (2) was treated with trimethylsilyl(TMS)acetylene under standard Hagihara-Sonogashira coupling conditions and subsequently deprotected with K2CO3 in MeOH/THF. As expected, the Pd-catalyzed coupling reaction runs under milder conditions and with higher

• PAH substituents (Scheme 3). Pd-catalyzed coupling of the diiodo compound 14 with the mono protected bisacetylene 20, deprotection of the acetylenes with TBAF and subsequent coupling with an excess of the diiodo compound 5c gave the diiodide 23. Hagihara-Sonogashira coupling of 23 with an excess of