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Search for "chiral amines" in Full Text gives 33 result(s) in Beilstein Journal of Organic Chemistry.

Efficient synthesis of β’-amino-α,β-unsaturated ketones

  • Isabelle Abrunhosa-Thomas,
  • Aurélie Plas,
  • Nishanth Kandepedu,
  • Pierre Chalard and
  • Yves Troin

Beilstein J. Org. Chem. 2013, 9, 486–495, doi:10.3762/bjoc.9.52

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  • under different protocols in which the stereoselectivity of the reaction can be introduced through the use of a chiral catalyst [9][10] (Lewis acid, Brønsted acids, L-proline, Cinchona alkaloids derivatives, thioureas, etc.), or by the addition of chiral amines to α,β-unsaturated esters [11][12] or the
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Published 06 Mar 2013

Rh(III)-catalyzed directed C–H bond amidation of ferrocenes with isocyanates

  • Satoshi Takebayashi,
  • Tsubasa Shizuno,
  • Takashi Otani and
  • Takanori Shibata

Beilstein J. Org. Chem. 2012, 8, 1844–1848, doi:10.3762/bjoc.8.212

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  • ]. Planar chiral 1,2-disubstituted ferrocene derivatives are usually synthesized by using diastereoselective ortho-lithiation of monosubstituted ferrocenes with an appropriate chiral ortho-directing substituent such as chiral amines, sulfoxides, and oxazolines [3]. However, this method suffers from low atom
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Published 29 Oct 2012

Automated three-component synthesis of a library of γ-lactams

  • Erik Fenster,
  • David Hill,
  • Oliver Reiser and
  • Jeffrey Aubé

Beilstein J. Org. Chem. 2012, 8, 1804–1813, doi:10.3762/bjoc.8.206

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  • protocol, we explored the use of various chiral amines in the conjugate addition reaction of propionaldehyde (2{1}) to N-phenylmaleimide (1{1}) (Table 1). Although the achiral pyrrolidine was found to be an efficient catalyst in the reaction [12], this led to a ~1:1 mixture of racemic succinimide
  • diastereomers 3{1,1}, even at lowered temperatures (Table 1, entries 1 and 2). While a number of chiral amines failed to produce any significant amounts of the desired succinimide product (Table 1, entries 3–9), we were pleased to find that the use of protected diphenylprolinol catalyst I at room temperature
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Published 19 Oct 2012

Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines

  • Chittaranjan Bhanja,
  • Satyaban Jena,
  • Sabita Nayak and
  • Seetaram Mohapatra

Beilstein J. Org. Chem. 2012, 8, 1668–1694, doi:10.3762/bjoc.8.191

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  • points of view: The conjugate addition of hetero-centered nucleophiles to α,β-unsaturated compounds; in a more complex approach through tandem/domino/cascade-Michael reactions; and by using chiral amines as organocatalysts for the enantioselective synthesis of functionalized chiral chromenes
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Published 04 Oct 2012

Highly enantioselective access to cannabinoid-type tricyles by organocatalytic Diels–Alder reactions

  • Stefan Bräse,
  • Nicole Volz,
  • Franziska Gläser and
  • Martin Nieger

Beilstein J. Org. Chem. 2012, 8, 1385–1392, doi:10.3762/bjoc.8.160

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  • )phenyl)thiourea, which gave a satisfying 60% yield. In order to optimize the yield and to introduce chiral elements, we screened a number of analogues. These thiourea catalysts 9a–l were easy to obtain from the corresponding isothiocyanates 7a,b and chiral amines 8a–f in a one-step synthesis (Scheme 1
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Published 28 Aug 2012

Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines

  • Luca Banfi,
  • Andrea Basso,
  • Valentina Cerulli,
  • Valeria Rocca and
  • Renata Riva

Beilstein J. Org. Chem. 2011, 7, 976–979, doi:10.3762/bjoc.7.109

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  • with chiral amines as auxiliaries [6], or with chiral cyclic imines. The use of cyclic imines (three-component Ugi–Joullié reaction) [7][8] is particularly useful, because the resulting Ugi products are necessarily nitrogen heterocycles. However, good diastereoselectivity has been obtained so far only
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Published 13 Jul 2011

Development of dynamic kinetic resolution on large scale for (±)-1-phenylethylamine

  • Lisa K. Thalén and
  • Jan-E. Bäckvall

Beilstein J. Org. Chem. 2010, 6, 823–829, doi:10.3762/bjoc.6.97

Graphical Abstract
  • donor. Keywords: dynamic kinetic resolution; kinetic resolution; racemization; Shvo; Candida antartica lipase B; Introduction Chiral amines are important building blocks in the synthesis of many pharmaceuticals, fragrances, and agricultural products, and it is therefore important to develop methods
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Published 13 Sep 2010

Molecular recognition of organic ammonium ions in solution using synthetic receptors

  • Andreas Späth and
  • Burkhard König

Beilstein J. Org. Chem. 2010, 6, No. 32, doi:10.3762/bjoc.6.32

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Published 06 Apr 2010
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