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Search for "continuous process" in Full Text gives 35 result(s) in Beilstein Journal of Organic Chemistry.
Flow synthesis of a versatile fructosamine mimic and quenching studies of a fructose transport probe
Beilstein J. Org. Chem. 2013, 9, 2022–2027, doi:10.3762/bjoc.9.238
- , a dilute aqueous solution of 1 resulted and overnight lyophilisation was required to isolate the product. Because the conditions are not easily integrated into a continuous process, we sought alternative approaches. Our initial approach was to continue using a resin (Amberlite IRA-900) supporting
One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor
Beilstein J. Org. Chem. 2013, 9, 1957–1968, doi:10.3762/bjoc.9.232
- . [47] have demonstrated that ethynyl ketones can be generated in flow by the palladium-catalysed acylation of terminal alkynes and further transformed in a continuous process to pyrazoles by cyclocondensation with hydrazines using a commercially available conductive heating modular flow reactor. Given
Integrating reaction and analysis: investigation of higher-order reactions by cryogenic trapping
Beilstein J. Org. Chem. 2013, 9, 1837–1842, doi:10.3762/bjoc.9.214
- direct analytical information about a reaction is obtained, including the formation of by-products and eventually even the reaction kinetics [1][2][3][4]. This information is important to design efficient flow-through experiments and to scale-up a reaction in a continuous process [5][6][7][8][9], which
Photochemistry with laser radiation in condensed phase using miniaturized photoreactors
Beilstein J. Org. Chem. 2012, 8, 1213–1218, doi:10.3762/bjoc.8.135
- was shown that a largely better selectivity can be achieved, compared to the one obtained in a standard UV irradiation setup (Figure 2). Experiments were performed in batch as well as flow-injection configuration. The continuous process used allowed us to vary the residence time in the reactor by
Continuous proline catalysis via leaching of solid proline
Beilstein J. Org. Chem. 2011, 7, 1671–1679, doi:10.3762/bjoc.7.197
- commonly used chloroform. We have a long standing interest in the conversion of the reaction into a continuous process, but recognized that the solubility of proline would hinder its use in flow. To circumvent this problem, we envisioned using a cartridge of solid proline as a precatalyst source, whereby
Coupled chemo(enzymatic) reactions in continuous flow
Beilstein J. Org. Chem. 2011, 7, 1449–1467, doi:10.3762/bjoc.7.169
- classified as first-generation enzymatic processes (Figure 2, I), which historically were the first to be applied in the chemical industry and till now remain the most abundant among industrial biotransformations. The second biological principle states that cell metabolism is a continuous process. Every
- the productivity of the second reactor at a constant level, which otherwise would drop down due to substrate-promoted cell inactivation and consequent cell wash-out. In the continuous process the productivity of yeast cells was improved compared to batch operation, giving a yield of 64.8% of the
Continuous preparation of carbon-nanotube-supported platinum catalysts in a flow reactor directly heated by electric current
Beilstein J. Org. Chem. 2011, 7, 1412–1420, doi:10.3762/bjoc.7.165
- Pt·cm−2. Both samples show a nearly equal open circuit voltage (OCV) of 660 mV. The current densities at 0.4 V were found to be 203 mA·cm−2 for Pt/CNT (tubular reactor) and 139 mA·cm−2 for Pt/CNT (oil bath). The cell containing the electrocatalyst synthesized in the continuous process exhibits a maximum
- oil-bath sample (12.65%). DMFC performance tests reveal excellent catalytic activity of the catalyst prepared in the continuous process, resulting in a measured maximum power density of 103 mW·cm−2 in comparison to 64 mW·cm−2 for the reference sample. This improvement in fuel cell performance can be
- Alicja Schlange Antonio Rodolfo dos Santos Ulrich Kunz Thomas Turek Institute of Chemical Process Engineering, Clausthal University of Technology, Leibnizstr.17, D-38678 Clausthal-Zellerfeld, Germany 10.3762/bjoc.7.165 Abstract In this contribution we present for the first time a continuous
Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids
Beilstein J. Org. Chem. 2011, 7, 1347–1359, doi:10.3762/bjoc.7.159
- potential of biphasic ILs–scCO2 systems. Indeed, this system was further implemented by the same authors to obtain a fully continuous process [20]. In this context, a simple approach to implement biphasic ILs–scCO2 systems into continuous flow processes is to absorb the ILs on a porous support material
Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
Beilstein J. Org. Chem. 2011, 7, 1048–1054, doi:10.3762/bjoc.7.120
- conditions that would convert all of the diketone substrate to a fluorodiketone in the first stage of the continuous process. Subsequent separation of fluoropyrazole (4a) from the corresponding non-fluorinated pyrazole, formed by the coupling of not reacted pentane-2,4-dione and hydrazine, was difficult to
The development and evaluation of a continuous flow process for the lipase- mediated oxidation of alkenes
Beilstein J. Org. Chem. 2009, 5, No. 27, doi:10.3762/bjoc.5.27
- synthetically useful alkenes, whilst increasing the biocatalyst’s lifetime. With this in mind, our initial investigation into the development of a continuous process for the synthesis of epoxides focussed on the incorporation of immobilised Candida antarctica lipase B, Novozym® 435 (4), into a flow reactor and
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