Search results

Search for "electrospray" in Full Text gives 183 result(s) in Beilstein Journal of Organic Chemistry.

Characterization of a new fusicoccane-type diterpene synthase and an associated P450 enzyme

  • Jia-Hua Huang,
  • Jian-Ming Lv,
  • Liang-Yan Xiao,
  • Qian Xu,
  • Fu-Long Lin,
  • Gao-Qian Wang,
  • Guo-Dong Chen,
  • Sheng-Ying Qin,
  • Dan Hu and
  • Hao Gao

Beilstein J. Org. Chem. 2022, 18, 1396–1402, doi:10.3762/bjoc.18.144

Graphical Abstract
  • , production of 1 was increased by five-fold (Figure 3A, line iii). Finally, we isolated 1 and 2 through large-scale fermentation. On the basis of the quasi-molecular ion at m/z 273.2599 [M + H]+ (calcd. for C20H33, 273.2582) (Supporting Information File 1, Figure S2) detected by high-resolution electrospray
PDF
Album
Supp Info
Full Research Paper
Published 05 Oct 2022

Cyclodextrin-based Schiff base pro-fragrances: Synthesis and release studies

  • Attila Palágyi,
  • Jindřich Jindřich,
  • Juraj Dian and
  • Sophie Fourmentin

Beilstein J. Org. Chem. 2022, 18, 1346–1354, doi:10.3762/bjoc.18.140

Graphical Abstract
  • 5-methylfurfural (2j) and 3.1 min for heptanal (2h). The mass spectra were measured by the Bruker ESQUIRE 3000 ES-ion trap and the samples were ionized using an electrospray technique (ESI). The samples were dissolved in methanol. Specific optical rotation was measured by the Rudolph Research
PDF
Supp Info
Full Research Paper
Published 28 Sep 2022

Experimental and theoretical studies on the synthesis of 1,4,5-trisubstituted pyrrolidine-2,3-diones

  • Nguyen Tran Nguyen,
  • Vo Viet Dai,
  • Nguyen Ngoc Tri,
  • Luc Van Meervelt,
  • Nguyen Tien Trung and
  • Wim Dehaen

Beilstein J. Org. Chem. 2022, 18, 1140–1153, doi:10.3762/bjoc.18.118

Graphical Abstract
  • electrospray ionization (ESI) source in a positive mode. The temperatures of the source were set at 300 °C. Curtain gas (25 psi) chambers were filled with high-purity nitrogen. The capillary voltage was constantly kept at 5500 V. Collision energies was set at 10 V and zero collision energy spread. IDA mode was
PDF
Album
Supp Info
Full Research Paper
Published 31 Aug 2022

Synthesis of N-phenyl- and N-thiazolyl-1H-indazoles by copper-catalyzed intramolecular N-arylation of ortho-chlorinated arylhydrazones

  • Yara Cristina Marchioro Barbosa,
  • Guilherme Caneppele Paveglio,
  • Claudio Martin Pereira de Pereira,
  • Sidnei Moura,
  • Cristiane Storck Schwalm,
  • Gleison Antonio Casagrande and
  • Lucas Pizzuti

Beilstein J. Org. Chem. 2022, 18, 1079–1087, doi:10.3762/bjoc.18.110

Graphical Abstract
  • electrospray ionization (ESI) source (MicrOTOF-QII, Bruker Scientific) in positive mode. The compounds were individually dissolved in a solution of 50% chromatographic grade MeCN and 50% deionized H2O + 0.1% formic acid. General experimental procedure for the synthesis of hydrazones 1a–i In a 100 mL round
PDF
Album
Supp Info
Full Research Paper
Published 23 Aug 2022

On Reuben G. Jones synthesis of 2-hydroxypyrazines

  • Pierre Legrand and
  • Yves L. Janin

Beilstein J. Org. Chem. 2022, 18, 935–943, doi:10.3762/bjoc.18.93

Graphical Abstract
  • description of the experimental set up is provided in Supporting Information File 1. The low-resolution mass spectra were obtained on an Agilent 1200 series LC/MSD system using an Agilent Jet-Stream atmospheric electrospray ionization system and the high-resolution mass spectra (HRMS) were obtained using a
PDF
Album
Supp Info
Full Research Paper
Published 29 Jul 2022

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity

  • Jamshid Amiri Moghaddam,
  • Huijuan Guo,
  • Karsten Willing,
  • Thomas Wichard and
  • Christine Beemelmanns

Beilstein J. Org. Chem. 2022, 18, 722–731, doi:10.3762/bjoc.18.72

Graphical Abstract
  • of the enzymatic products: UHPLC-HESI-HRMS measurement was performed on a Dionex Ultimate3000 system combined with a Q-Exactive Plus mass spectrometer (Thermo Scientific) with a heated electrospray ion source (HESI). Metabolite separation was carried out by reversed-phase liquid chromatography at 40
PDF
Album
Supp Info
Full Research Paper
Published 22 Jun 2022

Synthesis of a new water-soluble hexacarboxylated tribenzotriquinacene derivative and its competitive host–guest interaction for drug delivery

  • Man-Ping Li,
  • Nan Yang and
  • Wen-Rong Xu

Beilstein J. Org. Chem. 2022, 18, 539–548, doi:10.3762/bjoc.18.56

Graphical Abstract
  • recorded using either the ultrafleXtreme MALDI-TOF mass spectrometer (Bruker) with α-cyano-4-hydroxycinnamic acid (HCCA) as a matrix, or by electrospray ionization (ESI) on a Waters G2-XS QTOF instrument connected to a Waters H-class UPLC equipped with a Waters BEH C18 column using an eluent consisting of
PDF
Album
Supp Info
Full Research Paper
Published 12 May 2022

Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans-sialidase

  • Peterson de Andrade,
  • Sanaz Ahmadipour and
  • Robert A. Field

Beilstein J. Org. Chem. 2022, 18, 208–216, doi:10.3762/bjoc.18.24

Graphical Abstract
  • and 4.79 ppm in 1H NMR, respectively. High-resolution mass spectra were acquired using electrospray ionisation in a Waters Vion spectrometer with Waters Acquity LC–MS (positive mode). Fluorescence measurements were performed on a FLUOstar Omega Multi-Mode Microplate Reader. Expression and purification
PDF
Album
Supp Info
Full Research Paper
Published 17 Feb 2022

Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins

  • Jiang-Song Zhai and
  • Da-Ming Du

Beilstein J. Org. Chem. 2022, 18, 25–36, doi:10.3762/bjoc.18.3

Graphical Abstract
  • an Agilent 6520 Accurate-Mass Q-TOF MS system equipped with an electrospray ionization (ESI) source. Optical rotations were measured with a Krüss P8000 polarimeter at the indicated concentration with the units of g/100 mL. Enantiomeric excesses were determined by chiral HPLC analysis using an Agilent
PDF
Album
Supp Info
Full Research Paper
Published 04 Jan 2022

Synthesis of 1-indolyl-3,5,8-substituted γ-carbolines: one-pot solvent-free protocol and biological evaluation

  • Premansh Dudhe,
  • Mena Asha Krishnan,
  • Kratika Yadav,
  • Diptendu Roy,
  • Krishnan Venkatasubbaiah,
  • Biswarup Pathak and
  • Venkatesh Chelvam

Beilstein J. Org. Chem. 2021, 17, 1453–1463, doi:10.3762/bjoc.17.101

Graphical Abstract
  • -Performance LC-MS (electrospray ionization quadrupole time-of-flight) spectrometer. X-ray structure analysis was carried out at a Bruker KAPPA APEXII single crystal X-ray diffractometer. Melting points (mp) are uncorrected and were measured on a Veego melting point apparatus (capillary method). Analytical
PDF
Album
Supp Info
Letter
Published 17 Jun 2021

A new glance at the chemosphere of macroalgal–bacterial interactions: In situ profiling of metabolites in symbiosis by mass spectrometry

  • Marine Vallet,
  • Filip Kaftan,
  • Veit Grabe,
  • Fatemeh Ghaderiardakani,
  • Simona Fenizia,
  • Aleš Svatoš,
  • Georg Pohnert and
  • Thomas Wichard

Beilstein J. Org. Chem. 2021, 17, 1313–1322, doi:10.3762/bjoc.17.91

Graphical Abstract
  • algal surfaces and their metabolic activities can be monitored in situ or using an imprinting method by desorption electrospray ionisation mass spectrometry [17][18]. In U. mutabilis gametophytes, matrix-assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI) was used to identify cell
PDF
Album
Supp Info
Full Research Paper
Published 19 May 2021

Structural effects of meso-halogenation on porphyrins

  • Keith J. Flanagan,
  • Maximilian Paradiz Dominguez,
  • Zoi Melissari,
  • Hans-Georg Eckhardt,
  • René M. Williams,
  • Dáire Gibbons,
  • Caroline Prior,
  • Gemma M. Locke,
  • Alina Meindl,
  • Aoife A. Ryan and
  • Mathias O. Senge

Beilstein J. Org. Chem. 2021, 17, 1149–1170, doi:10.3762/bjoc.17.88

Graphical Abstract
  • quadrupole time-of-flight (Q-TOF) mass spectrometer equipped with Z-spray electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI) sources either in a positive or negative mode with DCTB (trans-2-[3-(4-tert-butylphenyl)-2-methyl-2-propenylidene]malononitrile) as the matrix. UV
PDF
Album
Supp Info
Full Research Paper
Published 14 May 2021

DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies

  • Yongdong Su,
  • Maitsetseg Bayarjargal,
  • Tracy K. Hale and
  • Vyacheslav V. Filichev

Beilstein J. Org. Chem. 2021, 17, 749–761, doi:10.3762/bjoc.17.65

Graphical Abstract
  • was confirmed by electrospray ionization mass spectrometry (ESIMS) in the negative mode (Table 1). For clarity, we introduced the following nomenclature of the ONs synthesised. The prefix 5ʼ- or 3ʼ- with either N+ or Ts- means that the first phosphate at the 5ʼ- or 3ʼ-end was modified; m-N+ or m-Ts
PDF
Album
Supp Info
Full Research Paper
Published 29 Mar 2021

19F NMR as a tool in chemical biology

  • Diana Gimenez,
  • Aoife Phelan,
  • Cormac D. Murphy and
  • Steven L. Cobb

Beilstein J. Org. Chem. 2021, 17, 293–318, doi:10.3762/bjoc.17.28

Graphical Abstract
  • ). Each independent intermediate was characterized on the basis of its 19F NMR chemical shift and the kinetics by which each species formed or decayed were evaluated in real-time. By combining the 19F NMR data with that provided by complementary analytical techniques, mass spectrometry (electrospray
PDF
Album
Review
Published 28 Jan 2021

Control over size, shape, and photonics of self-assembled organic nanocrystals

  • Chen Shahar,
  • Yaron Tidhar,
  • Yunmin Jung,
  • Haim Weissman,
  • Sidney R. Cohen,
  • Ronit Bitton,
  • Iddo Pinkas,
  • Gilad Haran and
  • Boris Rybtchinski

Beilstein J. Org. Chem. 2021, 17, 42–51, doi:10.3762/bjoc.17.5

Graphical Abstract
  • applicability of organic nanocrystals. Experimental General information The 1H and 13C NMR spectra were recorded at 20 °C on a 300 MHz NMR spectrometer (Bruker). Electrospray ionization (ESI) mass spectrometry was performed using a Micromass Platform instrument. UV–vis absorption and fluorescence measurements
PDF
Album
Supp Info
Full Research Paper
Published 06 Jan 2021

Naphthalonitriles featuring efficient emission in solution and in the solid state

  • Sidharth Thulaseedharan Nair Sailaja,
  • Iván Maisuls,
  • Jutta Kösters,
  • Alexander Hepp,
  • Andreas Faust,
  • Jens Voskuhl and
  • Cristian A. Strassert

Beilstein J. Org. Chem. 2020, 16, 2960–2970, doi:10.3762/bjoc.16.246

Graphical Abstract
  • characterized by nuclear magnetic resonance spectroscopy (NMR, Supporting Information File 1, Figures S1–S24) as well as exact electrospray mass spectrometry (EM–ESIMS, Supporting Information File 1, Figures S25–S30) and appear as white to faint yellow solids. Only the dimethylamino-substituted product shows a
PDF
Album
Supp Info
Full Research Paper
Published 02 Dec 2020

Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes

  • Dmitrii A. Aksenov,
  • Nikolai A. Arutiunov,
  • Vladimir V. Maliuga,
  • Alexander V. Aksenov and
  • Michael Rubin

Beilstein J. Org. Chem. 2020, 16, 2903–2910, doi:10.3762/bjoc.16.239

Graphical Abstract
  • DMSO-d6, using TMS as an internal standard. High-resolution mass spectra were obtained using a Bruker Maxis spectrometer (electrospray ionization, MeCN solution, using HCO2Na/HCO2H for calibration). Melting points were measured with a Stuart smp30 apparatus. All reactions were performed in oven-dried
PDF
Album
Supp Info
Full Research Paper
Published 26 Nov 2020

A heterobimetallic tetrahedron from a linear platinum(II)-bis(acetylide) metalloligand

  • Matthias Hardy,
  • Marianne Engeser and
  • Arne Lützen

Beilstein J. Org. Chem. 2020, 16, 2701–2708, doi:10.3762/bjoc.16.220

Graphical Abstract
  • , correlation of the proton. Low- and high-resolution electrospray ionization mass spectrometry (ESIMS) spectra were recorded on a Bruker Daltonic LTQ Orbitrap XL. The UV–vis spectrum was recorded on a Specord 200 spectrometer (Analytik Jena AG) at ambient temperature. 4-Ethynylaniline (1) [50], trans-[Pt(PBu3
PDF
Album
Supp Info
Full Research Paper
Published 03 Nov 2020

Water-soluble host–guest complexes between fullerenes and a sugar-functionalized tribenzotriquinacene assembling to microspheres

  • Si-Yuan Liu,
  • Xin-Rui Wang,
  • Man-Ping Li,
  • Wen-Rong Xu and
  • Dietmar Kuck

Beilstein J. Org. Chem. 2020, 16, 2551–2561, doi:10.3762/bjoc.16.207

Graphical Abstract
  • ppm in the 13C NMR spectrum were attributed to the acetylene protons and carbons, respectively. The electrospray ionization (ESI) mass spectrum showed the most intense peak at m/z 641.1923, which corresponds to the [M + Na]+ molecular adduct ion and matches well with the calculated value (m/z 641.1935
  • Instruments Co., Ltd, Shanghai, China). Mass spectra were recorded using either electrospray ionization (ESI) on a LCMS-IT-TOF instrument (Shimadzu, Kyoto, Japan) or a matrix-assisted laser desorption/ionization (MALDI) on a RapifleX MALDI Tissuetyper system (Bruker Daltonik GmbH, Bremen, Germany). Raman
PDF
Album
Supp Info
Full Research Paper
Published 14 Oct 2020

Leveraging glycomics data in glycoprotein 3D structure validation with Privateer

  • Haroldas Bagdonas,
  • Daniel Ungar and
  • Jon Agirre

Beilstein J. Org. Chem. 2020, 16, 2523–2533, doi:10.3762/bjoc.16.204

Graphical Abstract
  • ]. Typically, these analyses are based on mass spectrometry techniques, such as electrospray ionization mass spectrometry (ESIMS) and matrix-assisted laser desorption ionization MS (MALDIMS) [43]. Mass spectrometry techniques are best suited for the determination of the composition of monosaccharide classes
PDF
Album
Full Research Paper
Published 09 Oct 2020

Muyocopronones A and B: azaphilones from the endophytic fungus Muyocopron laterale

  • Ken-ichi Nakashima,
  • Junko Tomida,
  • Tomoe Tsuboi,
  • Yoshiaki Kawamura and
  • Makoto Inoue

Beilstein J. Org. Chem. 2020, 16, 2100–2107, doi:10.3762/bjoc.16.177

Graphical Abstract
  • . NMR spectra were acquired on a JEOL JNM-ECZ 400S spectrometer with tetramethylsilane as the internal standard. ESIMS data were obtained using an Agilent 6230B TOF LC/MS system equipped with an electrospray ion source (Agilent Technologies, CA, USA) and an Agilent 1260 infinity II LC (Agilent
PDF
Album
Supp Info
Full Research Paper
Published 28 Aug 2020

Clustering and curation of electropherograms: an efficient method for analyzing large cohorts of capillary electrophoresis glycomic profiles for bioprocessing operations

  • Ian Walsh,
  • Matthew S. F. Choo,
  • Sim Lyn Chiin,
  • Amelia Mak,
  • Shi Jie Tay,
  • Pauline M. Rudd,
  • Yang Yuansheng,
  • Andre Choo,
  • Ho Ying Swan and
  • Terry Nguyen-Khuong

Beilstein J. Org. Chem. 2020, 16, 2087–2099, doi:10.3762/bjoc.16.176

Graphical Abstract
  • of m/z 400–2000 was used, with an acquisition speed of 1 Hz, and the mass spectrometry was set at the following conditions: 2.75 kV electrospray ionization capillary voltage, 15 V cone voltage, 120 °C ion source temperature, 300 °C desolvation temperature, 800 L/h desolvation gas flow. A lockspray
PDF
Album
Supp Info
Full Research Paper
Published 27 Aug 2020

Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents

  • Paola Vitale,
  • Luciana Cicco,
  • Ilaria Cellamare,
  • Filippo M. Perna,
  • Antonio Salomone and
  • Vito Capriati

Beilstein J. Org. Chem. 2020, 16, 1915–1923, doi:10.3762/bjoc.16.158

Graphical Abstract
  • mass spectrometer equipped with an electrospray ion source (ESI). NaN3, 2-haloketones, and all other reagents, unless otherwise specified, were purchased from Sigma-Aldrich (Sigma-Aldrich, St. Louis, MO, USA), and used without any further purification. Experimental procedures General procedure for the
PDF
Album
Supp Info
Full Research Paper
Published 05 Aug 2020

Five-component, one-pot synthesis of an electroactive rotaxane comprising a bisferrocene macrocycle

  • Natalie Lagesse,
  • Luca Pisciottani,
  • Maxime Douarre,
  • Pascale Godard,
  • Brice Kauffmann,
  • Vicente Martí-Centelles and
  • Nathan D. McClenaghan

Beilstein J. Org. Chem. 2020, 16, 1564–1571, doi:10.3762/bjoc.16.128

Graphical Abstract
  • an FD emitter with an emitter voltage of 10 kV. The sample (1–2 µL) was deposited on a 13 μm emitter wire. Electrospray spectra (ESI) were recorded on a Qexactive (Thermo) mass spectrometer. The instrument was equipped with an ESI source and spectra were recorded in the positive mode. The spray
PDF
Album
Supp Info
Full Research Paper
Published 30 Jun 2020

Heterogeneous photocatalysis in flow chemical reactors

  • Christopher G. Thomson,
  • Ai-Lan Lee and
  • Filipe Vilela

Beilstein J. Org. Chem. 2020, 16, 1495–1549, doi:10.3762/bjoc.16.125

Graphical Abstract
  • stable HPCat for reductive dehalogenations and cyclisations, and reported its enhanced photocatalytic activity relative to unmodified TiO2 [151]. Electrochemical deposition techniques, such as electrospray and electrospinning, can also be applied to form photocatalytic composite materials. This has been
PDF
Album
Review
Published 26 Jun 2020
Other Beilstein-Institut Open Science Activities