Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids

• M. Isabel Burguete,
• Eduardo García-Verdugo and
• Santiago V. Luis

Beilstein J. Org. Chem. 2011, 7, 1347–1359, doi:10.3762/bjoc.7.159

• to a limited number of fields, a significant development in this area can be envisaged for the near future due to the clear advantages of these systems over the conventional ones. Keywords: biphasic systems; continuous flow processes; enantioselective catalysis; immobilized catalysts; polymer

Gold catalysis for organic synthesis

• F. Dean Toste

Beilstein J. Org. Chem. 2011, 7, 553–554, doi:10.3762/bjoc.7.63

• , cycloaddition and cycloisomerization reactions, to applications in enantioselective catalysis, oxidative coupling and the total synthesis of natural products, and transformations of alkynes, allenes, alkenes and even C–H bonds. A true treasure chest of reactivity! I am grateful to all of the authors that have

A superior P-H phosphonite: Asymmetric allylic substitutions with fenchol- based palladium catalysts

• Bernd Goldfuss,
• Thomas Löschmann,
• Tina Kop-Weiershausen,
• Jörg Neudörfl and
• Frank Rominger

Beilstein J. Org. Chem. 2006, 2, No. 7, doi:10.1186/1860-5397-2-7

• 29% ee, Table 1). To our knowledge, this is the first successful application of halogen phosphites as ligands in enantioselective catalysis [26]. The highest enantioselectivity however is achieved with the P-H phosphonite BIFOP-H (65% ee, Table 1). As in copper-catalyzed 1,4-additions of diethylzinc

An exceptional P-H phosphonite: Biphenyl- 2,2'-bisfenchylchlorophosphite and derived ligands (BIFOPs) in enantioselective copper- catalyzed 1,4-additions

• T. Kop-Weiershausen,
• J. Lex,
• J.-M. Neudörfl and
• B. Goldfuss

Beilstein J. Org. Chem. 2005, 1, No. 6, doi:10.1186/1860-5397-1-6

• the phosphorus atoms in biphenyl-2,2'-bisfenchylphosphites (BIFOPs) founds the special suitability for BIFOP-H (3) as P-H phosphonite ligand in transition metal catalysis. This points to promising applications of 3 or analogue P-H ligands in enantioselective catalysis. X-ray crystal structure of BIFOP