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Search for "C–H bond activation" in Full Text gives 55 result(s) in Beilstein Journal of Organic Chemistry.

N-Heterocyclic carbene–palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides

  • Ismail Özdemir,
  • Nevin Gürbüz,
  • Nazan Kaloğlu,
  • Öznur Doğan,
  • Murat Kaloğlu,
  • Christian Bruneau and
  • Henri Doucet

Beilstein J. Org. Chem. 2013, 9, 303–312, doi:10.3762/bjoc.9.35

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  • with heteroarenes. Keywords: aryl chlorides; atom-economy; CH bond activation; C–H functionalization; carbenes; palladium; pyrroles; Introduction N-Heterocyclic carbenes (NHC) have emerged as an important class of ligands in the development of homogeneous catalysis [1][2][3][4][5][6][7][8][9]. Such
  • palladium-catalyzed direct arylation of various heteroaromatics including pyrroles by a CH bond activation using aryl halides has met great success in recent years, allowing the synthesis of a wide variety of arylated heteroaromatics in only one step [20][21][22][23][24][25]. However, there are still
  • the palladium-catalyzed coupling of heteroarenes with aryl halides through a CH bond activation has been largely explored. On the other hand, the influence of carbene ligands for such couplings remains largely unexplored [40][41][42][43][44][45][46][47]. Quite congested N-heterocyclic carbene
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Published 12 Feb 2013

Synthesis of conformationally restricted glutamate and glutamine derivatives from carbonylation of orthopalladated phenylglycine derivatives

  • Esteban P. Urriolabeitia,
  • Eduardo Laga and
  • Carlos Cativiela

Beilstein J. Org. Chem. 2012, 8, 1569–1575, doi:10.3762/bjoc.8.179

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  • -amino acids [11][12][13], due to the extraordinary interest in these delicate molecules as building blocks of peptides and proteins, and because of their relevant biological activity. In this context, we have recently reported CH bond activation processes on a variety of arylglycines substituted at the
  • mild reaction conditions (1 atm CO, 25 °C) and, mainly, because it occurs through CH bond activation processes without the need to use prefunctionalized substrates. Typical aminocarbonylations catalysed by Pd usually start from the corresponding iodides or bromides, and require high CO pressures and
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Published 18 Sep 2012

C2-Alkylation of N-pyrimidylindole with vinylsilane via cobalt-catalyzed C–H bond activation

  • Zhenhua Ding and
  • Naohiko Yoshikai

Beilstein J. Org. Chem. 2012, 8, 1536–1542, doi:10.3762/bjoc.8.174

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Letter
Published 14 Sep 2012

Organocatalytic C–H activation reactions

  • Subhas Chandra Pan

Beilstein J. Org. Chem. 2012, 8, 1374–1384, doi:10.3762/bjoc.8.159

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  • transformations will not be covered in this review. Review Organocatalytic sp3 CH bond activation reactions Non-asymmetric variants tert-Amino effect: The “tert-amino effect” refers to the ring-closure reactions that proceed by redox processes for C–C and C–X bond formation within conjugated systems [7][8][9
  • enantioselectivity for their reaction [25]. Organocatalytic sp2 CH bond activation reactions The catalytic cross-coupling of arenes and aryl halides to construct biaryl compounds is an important area in synthetic organic chemistry. Transition-metal-catalyzed biaryl synthesis from unactivated arenes by C–H
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Published 27 Aug 2012

Efficient synthesis of 1,3-diaryl-4-halo-1H-pyrazoles from 3-arylsydnones and 2-aryl-1,1-dihalo-1-alkenes

  • Yiwen Yang,
  • Chunxiang Kuang,
  • Hui Jin,
  • Qing Yang and
  • Zhongkui Zhang

Beilstein J. Org. Chem. 2011, 7, 1656–1662, doi:10.3762/bjoc.7.195

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  • moderate to excellent yields. 1,3-Diaryl-4-halo-1H-pyrazoles are found to be important intermediates that can easily be converted into 1,2,5-triaryl-substituted pyrazoles via Pd-catalyzed CH bond activation. Keywords: CH bond activation; cycloaddition; dihaloalkenes; pyrazole; sydnones; Introduction
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Published 12 Dec 2011
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