OligArch: A software tool to allow artificially expanded genetic information systems (AEGIS) to guide the autonomous self-assembly of long DNA constructs from multiple DNA single strands

• Kevin M. Bradley and
• Steven A. Benner

Beilstein J. Org. Chem. 2014, 10, 1826–1833, doi:10.3762/bjoc.10.192

• of these fragments. Such engineered L-DNA might encode new and useful functions, including the manufacturing of biofuels, the synthesis of pharmaceuticals, and the development of new materials. As it is taught to non-chemists, DNA appears to be an ideal molecule for such “hands-off” self-assembly. In

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

• Sebastian Reinelt,
• Monir Tabatabai,
• Urs Karl Fischer,
• Norbert Moszner,
• Andreas Utterodt and
• Helmut Ritter

Beilstein J. Org. Chem. 2014, 10, 1733–1740, doi:10.3762/bjoc.10.180

• [13][14], siloranes [15] or spiroorthocarbonates [16] are worth to be mentioned. Since Sharpless et al. published their concept of click chemistry in 2001, these reactions gained growing impact on the design of new materials [17]. Besides the alkyne–azide reaction, especially thiol–ene reactions were

Aryl substitution of pentacenes

• Andreas R. Waterloo,
• Anna-Chiara Sale,
• Dan Lehnherr,
• Frank Hampel and
• Rik R. Tykwinski

Beilstein J. Org. Chem. 2014, 10, 1692–1705, doi:10.3762/bjoc.10.178

• to chemically assemble small organic molecules for such applications, clever design and synthesis have rapidly offered new materials for the nascent era of molecular electronic [4][5][6][7][8][9][10][11]. Prominent p-type organic semiconductors include substituted acenes in general [12][13][14][15

Reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithiethane with N-vinyl compounds

• Viacheslav A. Petrov and
• Will Marshall

Beilstein J. Org. Chem. 2013, 9, 2615–2619, doi:10.3762/bjoc.9.295

• reported in [12] and was used without further purification. Due to the high ratio of sulfur to fluorine, the elemental analysis of new materials was not attempted. The purity of all new compounds established by GC and NMR spectroscopy was at least 98%. Crystallography X-ray data for 3b, 3e and 5a were

Studies on the photodegradation of red, green and blue phosphorescent OLED emitters

• Susanna Schmidbauer,
• Andreas Hohenleutner and
• Burkhard König

Beilstein J. Org. Chem. 2013, 9, 2088–2096, doi:10.3762/bjoc.9.245

• development of highly stable phosphorescent dopants is therefore a topic of high interest. Thus, investigating the mechanisms and pathways responsible for the degradation of these materials is of high importance as the insights from these studies can guide the development of new materials with enhanced

The first example of the Fischer–Hepp type rearrangement in pyrimidines

• Inga Cikotiene,
• Mantas Jonusis and
• Virginija Jakubkiene

Beilstein J. Org. Chem. 2013, 9, 1819–1825, doi:10.3762/bjoc.9.212

• group transfer reactions in 6,-N-disubstituted-N-nitrosopyrimidin-4-amines. Data on the one-pot nucleophilic substitution/nitroso group transfer reactions in 6-chloro-N-disubstituted-N-nitrosopyrimidin-4-amines. Supporting Information Supporting Information File 316: Detailed data of all new materials

Highly stereocontrolled synthesis of trans-enediynes via carbocupration of fluoroalkylated diynes

• Tsutomu Konno,
• Misato Kishi and
• Takashi Ishihara

Beilstein J. Org. Chem. 2012, 8, 2207–2213, doi:10.3762/bjoc.8.249

• -enediynes [4][5][6][7], although the introduction of fluorine atom(s) into organic molecules very often changes their physical as well as chemical characteristics significantly, resulting in the discovery of new materials with unique physical properties [8][9][10][11][12][13][14]. In this paper we report a

Cyclodextrin-based nanosponges as drug carriers

• Francesco Trotta,
• Marco Zanetti and
• Roberta Cavalli

Beilstein J. Org. Chem. 2012, 8, 2091–2099, doi:10.3762/bjoc.8.235

• . After incubation with nanosponges no cytotoxicity was observed. The percentage of cell viability did not change from untreated cells. Other in vitro methods for evaluating the toxicity of new materials include the determination of its haemolytic properties. When nanosponges were incubated with human

Cyclodextrin nanosponge-sensitized enantiodifferentiating photoisomerization of cyclooctene and 1,3-cyclooctadiene

• Wenting Liang,
• Cheng Yang,
• Masaki Nishijima,
• Gaku Fukuhara,
• Tadashi Mori,
• Andrea Mele,
• Franca Castiglione,
• Fabrizio Caldera,
• Francesco Trotta and
• Yoshihisa Inoue

Beilstein J. Org. Chem. 2012, 8, 1305–1311, doi:10.3762/bjoc.8.149

• spectra shifting to higher wavenumbers. On the other hand, the stiffness of the polymeric network of CDNSs is more affected by the PMA/CD ratio, rather than the type of CD used. The adsorption, absorption and inclusion properties of these new materials have been demonstrated for a large variety of

Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of “super-trifluoromethyl” arene chemistry and its industry

• Teruo Umemoto,
• Lloyd M. Garrick and
• Norimichi Saito

Beilstein J. Org. Chem. 2012, 8, 461–471, doi:10.3762/bjoc.8.53

• attracted considerable interest in many areas such as medicines, agrochemicals, and other new materials, since the highly stable SF5 group is considered a “super-trifluoromethyl group” due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for

Perhydroazulene-based liquid-crystalline materials with smectic phases

• Zakir Hussain,
• Henning Hopf and
• S. Holger Eichhorn

Beilstein J. Org. Chem. 2012, 8, 403–410, doi:10.3762/bjoc.8.44

• narrow temperature ranges. The dependence of the mesogenic behavior of the new materials on the stereochemistry of the core system was also investigated. All newly synthesized compounds were fully characterized by the usual spectroscopic and analytical methods. Keywords: hydroazulenes; liquid crystals

Liquid-crystalline nanoparticles: Hybrid design and mesophase structures

• Gareth L. Nealon,
• Romain Greget,
• Cristina Dominguez,
• Zsuzsanna T. Nagy,
• Daniel Guillon,
• Jean-Louis Gallani and
• Bertrand Donnio

Beilstein J. Org. Chem. 2012, 8, 349–370, doi:10.3762/bjoc.8.39

• .8.39 Abstract Liquid-crystalline nanoparticles represent an exciting class of new materials for a variety of potential applications. By combining supramolecular ordering with the fluid properties of the liquid-crystalline state, these materials offer the possibility to organise nanoparticles into

• new materials, and to appreciate some of the early trends that are appearing in this relatively young and exciting field of endeavour. Review Design considerations In order for a nanoparticle sample to exhibit a thermotropic liquid-crystalline phase, it is necessary to first coat the NPs with a

• information storage applications, and could lead to the development of new materials with novel magnetic properties. In another report in which a similar approach was utilised [85] the synthesis and functionalisation of pseudospherical magnetic ferrite NPs [87] with pro-mesogenic ligands was described. The

Laterally substituted symmetric and nonsymmetric salicylideneimine-based bent-core mesogens

• Sonja Findeisen-Tandel,
• Wolfgang Weissflog,
• Ute Baumeister,
• Gerhard Pelzl,
• H. N. Shreenivasa Murthy and
• Channabasaveshwar V. Yelamaggad

Beilstein J. Org. Chem. 2012, 8, 129–154, doi:10.3762/bjoc.8.15

• and OH 4b and 4d are new materials. As seen from Table 4, the nature of the mesophase changes upon introduction of the hydroxy groups, from a crystal-like BX phase to a SmCP phase (H 4c to OH 4c) and from a nematic phase to an undulated SmCP phase (H 4b to OH 4b). In the case of the 5-methoxy

Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D

• Charles Dylan Turner and
• Marco A. Ciufolini

Beilstein J. Org. Chem. 2011, 7, 1475–1485, doi:10.3762/bjoc.7.171

• revolutionized the business of producing elaborate aromatic compounds, both in the academic laboratory and in the industrial plant, and that continue to produce countless benefits to society in the form of new medicines and new materials. Structure of nothapodytine B. Structures of topopyrones. Structure and

Syntheses and properties of thienyl-substituted dithienophenazines

• Annemarie Meyer,
• Eva Sigmund,
• Friedhelm Luppertz,
• Gregor Schnakenburg,
• Immanuel Gadaczek,
• Thomas Bredow,
• Stefan-S. Jester and
• Sigurd Höger

Beilstein J. Org. Chem. 2010, 6, 1180–1187, doi:10.3762/bjoc.6.135

• -acceptor (DA) approach), thereby red-shifting the absorption edge. This is of special importance, as there is still a need for new materials (exhibiting additionally the above mentioned processability criteria) absorbing the longer wavelength region (> 600 nm) of the sunlight spectrum, being required for

Ring-alkyl connecting group effect on mesogenic properties of p-carborane derivatives and their hydrocarbon analogues

• Aleksandra Jankowiak,
• Piotr Kaszynski,
• William R. Tilford,
• Kiminori Ohta,
• Adam Januszko,
• Takashi Nagamine and
• Yasuyuki Endo

Beilstein J. Org. Chem. 2009, 5, No. 83, doi:10.3762/bjoc.5.83

• -carboranes A and B (Figure 1) in the context of fundamental and applied studies of liquid crystals and development of new materials for electrooptical applications [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. p-Carboranes belong to an extensive family of closo-boranes

• fluorination [18][19] on mesophase stability, and also the effectiveness of shielding of a lateral substituent [8][16][20] and chirality transfer phenomena [17]. Results of these studies are important for the design of new materials and optimizing of their properties for applications. During our investigation

Low temperature enantiotropic nematic phases from V-shaped, shape-persistent molecules

• Matthias Lehmann and
• Jens Seltmann

Beilstein J. Org. Chem. 2009, 5, No. 73, doi:10.3762/bjoc.5.73

• ]. This has been recently confirmed by various other methods [11][12][13][14]. Since then several new materials have been designed and reported to be biaxial, among others tetrapodes [15][16][17] and banana-shaped oligoesters [18][19]. However, there is still a controversial discussion about the phase

Gold film- catalysed benzannulation by Microwave- Assisted, Continuous Flow Organic Synthesis (MACOS)

• Gjergji Shore,
• Michael Tsimerman and
• Michael G. Organ

Beilstein J. Org. Chem. 2009, 5, No. 35, doi:10.3762/bjoc.5.35

• and suitable physical robustness to prepare quantities of product suitable, for example, for biological or material science evaluation purposes (up to ~700 mg). The reaction showed wide functional group tolerance and good to excellent regioselectivity in the cycloaddition. We are now evaluating new

• materials to replace the glass tube with the plan of making the process more sustainable. Experimental Microwave irradiation experiments All MACOS experiments were performed in 1700 μm (ID) borosilicate capillaries, using a single mode Biotage Smith Creator Synthesizer, operating at a frequency of 2.45 GHz

Synthesis of 2,3,6,7-tetrabromoanthracene

• Christian Schäfer,
• Friederike Herrmann and
• Jochen Mattay

Beilstein J. Org. Chem. 2008, 4, No. 41, doi:10.3762/bjoc.4.41

• cyclization. This tetrabromide constitutes an excellent precursor for 2,3,6,7-tetrasubstituted anthracenes due to the bromine groups and it is also a candidate precursor to 2,3,6,7,9,10-hexabromoanthracene because of the high reactivity of the 9,10-positions. In addition, new materials may also be accessible