Recent advances in the electrochemical construction of heterocycles

• Robert Francke

Beilstein J. Org. Chem. 2014, 10, 2858–2873, doi:10.3762/bjoc.10.303

• approach proceeds reagent- and catalyst-free. Both electron-rich and electron-deficient olefins can be efficiently converted. The electrolysis is carried out under potentiostatic conditions in a divided cell at room temperature using a platinum working electrode. A mixture of triethylamine and glacial

A catalyst-free multicomponent domino sequence for the diastereoselective synthesis of (E)-3-[2-arylcarbonyl-3-(arylamino)allyl]chromen-4-ones

• Pitchaimani Prasanna,
• Pethaiah Gunasekaran,
• Subbu Perumal and
• J. Carlos Menéndez

Beilstein J. Org. Chem. 2014, 10, 459–465, doi:10.3762/bjoc.10.43

• Madrid, Spain 10.3762/bjoc.10.43 Abstract The three-component domino reactions of (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones, 3-formylchromone and anilines under catalyst-free conditions afforded a library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones in good to excellent yields

α-Bromodiazoacetamides – a new class of diazo compounds for catalyst-free, ambient temperature intramolecular C–H insertion reactions

• Åsmund Kaupang and
• Tore Bonge-Hansen

Beilstein J. Org. Chem. 2013, 9, 1407–1413, doi:10.3762/bjoc.9.157

• ]. In terms of their application in synthesis, the need for prolonged heating may have narrowed the substrate scope of thermolysis reactions considerably, contributing to the limited number of reports of catalyst-free thermolyses of diazo compounds in the literature. In comparison, the capability of the

A one-pot catalyst-free synthesis of functionalized pyrrolo[1,2-a]quinoxaline derivatives from benzene-1,2-diamine, acetylenedicarboxylates and ethyl bromopyruvate

• Mohammad Piltan,
• Loghman Moradi,
• Golaleh Abasi and
• Seyed Amir Zarei

Beilstein J. Org. Chem. 2013, 9, 510–515, doi:10.3762/bjoc.9.55

• Mohammad Piltan Loghman Moradi Golaleh Abasi Seyed Amir Zarei Department of Chemistry, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran Department of Chemistry, University of Kurdistan, Sanandaj, Iran 10.3762/bjoc.9.55 Abstract The catalyst-free multicomponent reaction of 1,2

• acetylenedicarboxylates in the presence of ethyl bromopyruvate provides a simple, catalyst-free one-pot entry to the synthesis of pyrrolo[1,2-a]quinoxaline derivatives having potential synthetic and pharmacological interest. The simplicity of the present procedure makes it an interesting alternative to other approaches

Iron-containing mesoporous aluminosilicate catalyzed direct alkenylation of phenols: Facile synthesis of 1,1-diarylalkenes

• Satyajit Haldar and
• Subratanath Koner

Beilstein J. Org. Chem. 2013, 9, 49–55, doi:10.3762/bjoc.9.6

• phenol and phenylacetylene was performed until 22% conversion was observed (monitored by GC analysis) and then the catalyst was separated by simple centrifugation under the hot conditions. No conversion in the “catalyst-free centrifugate” was observed upon further heating for 12 hours. Another most

Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

• Zong-Bo Xie,
• Na Wang,
• Ming-Yu Wu,
• Ting He,
• Zhang-Gao Le and
• Xiao-Qi Yu

Beilstein J. Org. Chem. 2012, 8, 534–538, doi:10.3762/bjoc.8.61

• yields by a grinding method under catalyst- and solvent-free conditions. Keywords: catalyst-free; grinding; Michael addition; solvent-free; Introduction Nowadays, chemists are vigorously taking on the challenge of developing green synthetic methodologies to meet the criteria of sustainable

• [22], a transition-metal-free process for the synthesis of substituted dihydrofurans [23] and a catalyst-free tandem reaction for the synthesis of 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones in aqueous medium [24]. Recently, when carrying out the reaction of β-nitrostyrene with 1,3-cyclopentanedione under