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Search for "fluorescent" in Full Text gives 427 result(s) in Beilstein Journal of Organic Chemistry. Showing first 200.
Microelectrode arrays, electrosynthesis, and the optimization of signaling on an inert, stable surface
Beilstein J. Org. Chem. 2022, 18, 1488–1498, doi:10.3762/bjoc.18.156
- peptides were placed on the array along with a fluorescent dye (LRSC, lissamine rhodamine) that was used to make sure the placement chemistry was working. The array used was coated with the borate ester diblock copolymer (Figure 2), and the peptides were attached to this polymer through a PEG-6 linker in
- . 4 cycles. Quantitative fluorescent study on variance of the polymer coating across the microelectrode surface. Purple represents blocks from the top region. Blue represents blocks from the center region. Orange represents blocks from the bottom region. An initial study and the comparison of an R6A
Mechanochemical synthesis of unsymmetrical salens for the preparation of Co–salen complexes and their evaluation as catalysts for the synthesis of α-aryloxy alcohols via asymmetric phenolic kinetic resolution of terminal epoxides
Beilstein J. Org. Chem. 2022, 18, 1416–1423, doi:10.3762/bjoc.18.147
- addition, a Lewis basic NEt2 (‒N(CH2CH3)2) group was introduced to the salen scaffold to facilitate purification, enhance catalytic efficiency, and improve the thermal stability, as was shown in the synthesis of fluorescent probes [41][42]. The chelating effect of salen compounds 1 with different metals
Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groups
Beilstein J. Org. Chem. 2022, 18, 1322–1331, doi:10.3762/bjoc.18.137
- overcome this issue is to use fluorescence emission as a read-out tool, such as an emission “on” or “off” behavior [15]. Selective and sensitive fluorescent ligands have been proven to be essential tools for the study of biological systems by biosensing and imaging [16]. There is an increasing demand for
Ionic multiresonant thermally activated delayed fluorescence emitters for light emitting electrochemical cells
Beilstein J. Org. Chem. 2022, 18, 1311–1321, doi:10.3762/bjoc.18.136
- ), Universidad de Valencia, C/Catedrático J. Beltrán 2, 46980 Paterna (Valencia), Spain School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, UK 10.3762/bjoc.18.136 Abstract We designed and synthesized two new ionic thermally activated delayed fluorescent (TADF) emitters that are charged analogues of
- in organic light-emitting diodes (OLEDs), relatively little attention has been devoted to the design of ionic small molecule (SM) [13] organic emitters for LEECs. The majority of the reported SM emitters for LEECs are fluorescent in nature and so the internal quantum efficiency (IQE) of the device is
- limited to 25% [13]. Thermally activated delayed fluorescent (TADF) emitters are one class of purely organic materials that can harvest triplet excitons in electroluminescent (EL) devices through a triplet to singlet reverse intersystem crossing (RISC) upconversion process [14]. Indeed, OLEDs using TADF
Polymer and small molecule mechanochemistry: closer than ever
Beilstein J. Org. Chem. 2022, 18, 1225–1235, doi:10.3762/bjoc.18.128
- fluorescent 9-fluorenone (3) via β-scission (Scheme 1b). To highlight the importance of the polymer network in the transduction of the mechanical stimulus to the mechanophore, the authors demonstrated that ball milling monomeric BMPF-OH at 30 Hz for 3 h only generated traces of 3 (1% after isolation
Synthesis, optical and electrochemical properties of (D–π)2-type and (D–π)2Ph-type fluorescent dyes
Beilstein J. Org. Chem. 2022, 18, 1047–1054, doi:10.3762/bjoc.18.106
- Kosuke Takemura Kazuki Ohira Taiki Higashino Keiichi Imato Yousuke Ooyama Applied Chemistry Program, Graduate School of Advanced Science and Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527, Japan 10.3762/bjoc.18.106 Abstract The (D–π)2-type fluorescent dye OTT-2
- with two (diphenylamino)carbazole-thiophene units as D (electron-donating group)–π (π-conjugated bridge) moiety and the (D–π)2Ph-type fluorescent dye OTK-2 with the two D–π moieties connected through a phenyl ring were derived by oxidative homocoupling of a stannyl D–π unit and Stille coupling of a
- band, but also intense fluorescence emission both in solution and the solid state. Keywords: (D–π)2 structure; fluorescence; fluorescent dyes; photoabsorption; redox properties; Introduction The design and development of a new type of organic fluorescent dyes have been of considerable scientific and
Electrochemical and spectroscopic properties of twisted dibenzo[g,p]chrysene derivatives
Beilstein J. Org. Chem. 2022, 18, 963–971, doi:10.3762/bjoc.18.96
- , a strong photoluminescence was observed for DBC-H and DBC-Si. Keywords: DFT calculation; dibenzo[g,p]chrysenes; fluorescent compounds; oxidation; polycyclic aromatic hydrocarbon (PAH); twisted acenes; Introduction Polycyclic aromatic hydrocarbons (PAHs) have attracted interest as potential
Introducing a new 7-ring fused diindenone-dithieno[3,2-b:2',3'-d]thiophene unit as a promising component for organic semiconductor materials
Beilstein J. Org. Chem. 2022, 18, 944–955, doi:10.3762/bjoc.18.94
- (the basic unit of processors) [6], solar cells, and LEDs [7]. Inorganic compounds, e.g. III-V type inorganics are widely used, however, in recent years, organic molecules with semiconducting and fluorescent properties have emerged as an alternative with advantages such as solution processing [8][9][10
Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products
Beilstein J. Org. Chem. 2022, 18, 926–934, doi:10.3762/bjoc.18.92
- . The present work is a step towards this and assimilates the results related to the exploration of 3-formyl-9H-β-carbolines for the synthesis of β-carboline C-3 substituted MBH adducts followed by evaluation of their fluorescent characteristic. The effect of contact time, solvent system, concentration
- relationships were concluded which are outlined in Figure 6. It was concluded from the structure–fluorescence activity relationships of C-3-substituted pyrido[3,4-b]indole derivatives that the products with o-bromophenyl substituent at R1 position (7cB and 7cE) were the most fluorescent derivatives among all
- . Also, substituted phenyl derivatives were more fluorescent than the dimethoxymethyl substituted derivatives 7aA–7aE. Further, it was observed that an ethyl substituent at N-9 position of β-carboline decreased the fluorescence intensity in 10eA–10eB than 7eD which is a N-unsubstituted derivative while
Post-synthesis from Lewis acid–base interaction: an alternative way to generate light and harvest triplet excitons
Beilstein J. Org. Chem. 2022, 18, 825–836, doi:10.3762/bjoc.18.83
- Guangdong Province, Shantou University, Shantou 518060, People’s Republic of China Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, People’s Republic of China 10.3762/bjoc.18.83 Abstract The changes in absorption and emission of fluorescent
- fluorescent materials containing Lewis basic nitrogen heterocycles are more likely to provide the feasible band gap modulation. The essence of such phenomenon originates from Lewis acid–base coordination and adducts, which highly depends on the electron-accepting property of the Lewis acids. This
- are fluorescent compounds. Based on the spin statistics, the fluorescent emitters can only use singlet excitons for light generation [5]. In contrast, phosphorescent materials based on metal complexes could achieve a high internal quantum efficiency (IQE) up to 100% through intersystem crossing (ISC
Syntheses of novel pyridine-based low-molecular-weight luminogens possessing aggregation-induced emission enhancement (AIEE) properties
Beilstein J. Org. Chem. 2022, 18, 580–587, doi:10.3762/bjoc.18.60
- the electronic nature of the compounds with and without AIEE properties. Keywords: acceptor–donor–acceptor; AIEE; low molecular weight; one-pot reaction; ((pyridin-2-yl)amino)maleimide; TD-DFT calculation; Introduction Fluorescent compounds have attracted considerable attention as functional
- -concentration solutions, and their emission efficiency, chromogenic properties, and light sensitivity decrease rapidly [5][6]. In recent years, contrary to conventional fluorescent compounds, aggregation-induced emission enhancement (AIEE)-based compounds that exhibit strong fluorescence in aggregate structures
- have been reported [7][8][9][10]. Because the aggregated state of AIEE-based compounds is affected by the external environment, these compounds have found use in clinical applications as chemical sensors or fluorescent probes [7][8][9][10]. Pyridine is a nitrogen-containing heterocyclic compound found
Comparative study of thermally activated delayed fluorescent properties of donor–acceptor and donor–acceptor–donor architectures based on phenoxazine and dibenzo[a,j]phenazine
Beilstein J. Org. Chem. 2022, 18, 459–468, doi:10.3762/bjoc.18.48
- efficiency (EQE) exceeds the theoretical maximum of those with prompt fluorescent emitters. Most importantly, comparative study of the D–A molecule and its D–A–D counterpart from the viewpoints of the experiments and theoretical calculations revealed the effect of the number of the electron donor on the
- thermally activated delayed fluorescent behavior. Keywords: charge-transfer; dibenzophenazine; donor–acceptor; organic light-emitting diodes; thermally activated delayed fluorescence; Introduction Thermally activated delayed fluorescence (TADF), which was firstly reported in 1961 by Parker and Hatchard [1
- achieved a good EQE up to 11%, which exceeds the theoretical maximum (ca. 5%) of prompt fluorescent emitter-based OLEDs. The additional donor gave a better EQE of the OLED device than that fabricated with the D–A compound, due to a less efficient TADF process. Taken together the experimental and
Menadione: a platform and a target to valuable compounds synthesis
Beilstein J. Org. Chem. 2022, 18, 381–419, doi:10.3762/bjoc.18.43
- source was made after preliminary studies demonstrated the occurrence of reactions with benzoquinones using the compact fluorescent lamp (Scheme 18). Reduction and acylation reactions Menadione reduction reactions are one of the most important types of reactions and are directly related to some of its
Four bioactive new steroids from the soft coral Lobophytum pauciflorum collected in South China Sea
Beilstein J. Org. Chem. 2022, 18, 374–380, doi:10.3762/bjoc.18.42
- value of 19.03 μM. The investigation of anti-inflammatory activities of lobophysterols E–H with classic transgenic fluorescent zebrafish models (Figure 5) showed that compound 1 exhibited moderate activity, with an inhibition rate of 32% (20 μM). Conclusion In conclusion, four new steroids
- were cultivated by Qilu University of Technology (Jinan, China). Transgenic zebrafish [Tg: zlyz-EGFP and Tg (vegfr2: GFP)] expressing enhanced green fluorescent protein (EGFP) was used in this article. The conditions of the maintenance complied with guidelines of the Organization for Economic Co
Recent developments and trends in the iron- and cobalt-catalyzed Sonogashira reactions
Beilstein J. Org. Chem. 2022, 18, 262–285, doi:10.3762/bjoc.18.31
- ) moiety since it can easily undergo aggregation-induced emission enhancement (AIEE). The self-assembly of the HPB derivative resulted in the formation of fluorescent aggregates, which can act as a stabilizer or as a reactor for the development of α-Fe2O3 nanoparticles at room temperature. The catalytic
- , Balla and co-workers discussed the scope of the reaction by the utilization of in-situ generated α-Fe2O3 nanoparticles with several activated and unactivated halides (Scheme 13) [30]. They also examined the effect of concentration of fluorescent aggregates of HPB, i.e., the size of the generated
Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans-sialidase
Beilstein J. Org. Chem. 2022, 18, 208–216, doi:10.3762/bjoc.18.24
- , followed by addition of 0.5 mM MUNANA (20 μL, 0.1 mM final concentration) and incubated at 37 °C for 15 min. The fluorescent product released (MU) was measured with excitation and emission wavelengths of 360 and 460 nm, respectively. Neuraminidase (10 mU) assay was performed as described above without
First total synthesis of hoshinoamide A
Beilstein J. Org. Chem. 2021, 17, 2924–2931, doi:10.3762/bjoc.17.201
- hoshinoamide A and other highly methylated polypeptide analogues. Our strategy was also helpful to further study its antimalarial activity. Structure-and-activity and functional studies with the fluorescent-labeled analogs are currently under investigation in our lab. Experimental General experimental
Synthesis of a novel aminobenzene-containing hemicucurbituril and its fluorescence spectral properties with ions
Beilstein J. Org. Chem. 2021, 17, 2840–2847, doi:10.3762/bjoc.17.195
- produced the desired amidobenzene-containing hemicucurbituril. As an original fluorescent chemosensor, it exhibited strong interactions with Fe3+ over other metal cations. The experimental evidence of fluorescence spectra suggested that a 1:1 complex was formed between this macrocycle and Fe3+ with an
Synthesis of phenanthridines via a novel photochemically-mediated cyclization and application to the synthesis of triphaeridine
Beilstein J. Org. Chem. 2021, 17, 2340–2347, doi:10.3762/bjoc.17.152
- captivated synthetic chemists and biologists alike since the 1960s due to their efficient DNA binding, antitumour and antiparasitic activities [1]. Such compounds include the DNA and RNA-fluorescent marker ethidium bromide (1), the cell viability probe propidium iodide (2) and the naturally occurring
Post-functionalization of drug-loaded nanoparticles prepared by polymerization-induced self-assembly (PISA) with mitochondria targeting ligands
Beilstein J. Org. Chem. 2021, 17, 2302–2314, doi:10.3762/bjoc.17.148
- -((phenylcarbonothioyl)thio)pentanoic acid, but it was modified with ethylene glycol. During the polymerization of the water-soluble polymers, fluorescein O-methacrylate was added at a ratio of CTA to fluorescent monomer of 1:0.3. This means more that three out of ten polymer chains will be labelled, which is sufficient
Transition-metal-free intramolecular Friedel–Crafts reaction by alkene activation: A method for the synthesis of some novel xanthene derivatives
Beilstein J. Org. Chem. 2021, 17, 2203–2208, doi:10.3762/bjoc.17.142
- used in pH-sensitive fluorescent materials [10] and laser technologies [11][12][13][14]. Moreover, xanthenes are present in some natural sources, such as santalin pigments found in many varieties of plants [15][16]. There have been many studies on the synthesis of xanthene derivatives to date because
- of their important biological and fluorescent uses. To summarize the main syntheses of these studies: in particular, transition metal-catalyzed cascade benzylation–cyclization [17], cyclization of polycyclic aryl triflate esters [18], reaction of β-naphthol and aldehydes [19][20] or inter- or
Chemical syntheses and salient features of azulene-containing homo- and copolymers
Beilstein J. Org. Chem. 2021, 17, 2164–2185, doi:10.3762/bjoc.17.139
- , respectively. The UV–vis absorption features of polymers 115 and 116 were altered upon protonation due to the formation of azulenium cations in the polymer backbone and they displayed a significant color change on protonation. None of these polymers were fluorescent in the neutral form, however, 115 and 116
Recent advances in the syntheses of anthracene derivatives
Beilstein J. Org. Chem. 2021, 17, 2028–2050, doi:10.3762/bjoc.17.131
- [11][12], the 2,2’-bianthracene derivative 3 provides a green and fluorescent OLED [13], 2,2’-bianthracenyl (4) has been employed as an organic semiconductor in an OFET device [14], and di-n-alkoxyanthracenes have gelling properties with diverse solvents, mainly alkanes and alcohols [4]. Furthermore
- activity for iodoethynyl groups [63]. Intramolecular cyclization In 2009, Swager’s research group published the synthesis of fluorescent macrocycles based on 1,3-butadiyne-bridged dibenzo[a,j]anthracene subunits via a multistep route (Scheme 30) [64]. They synthesized substituted dibenzo[a,j]anthracenes
Asymmetric organocatalyzed synthesis of coumarin derivatives
Beilstein J. Org. Chem. 2021, 17, 1952–1980, doi:10.3762/bjoc.17.128
- acetylcholinesterase inhibitors [11][12][13], being LSPN223 the most potent compound (Figure 2). Furthermore, coumarin derivatives have been used as fluorescent probes, laser dyes, fluorescent chemosensors, light absorbers for solar cells, optical brighteners, and organic light emitting diodes (OLEDs) [14][15]. From a
Sustainable manganese catalysis for late-stage C–H functionalization of bioactive structural motifs
Beilstein J. Org. Chem. 2021, 17, 1733–1751, doi:10.3762/bjoc.17.122
- adjacent directing group (see 31h). This manganese(I)-catalyzed late-stage glycosylation provides hexaglycopeptide conjugate 31m without epimerization. Moreover, the late-stage C–H diversification process enabled bioorthogonal access to glycosylated peptides, such as a fluorescent BODIPY-labeled tryptophan
- , fluorinations, allylations, alkynylations, alkenylations, and fluorescent labeling with BODIPY. Moreover, manganese catalysis exhibits excellent functional group tolerance in late-stage C–H functionalization, indicating a robust and versatile catalytic system. Several challenges still remain since there are
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