Synthesis and glycosidase inhibitory activity of new hexa- substituted C8-glycomimetics

• Olivia Andriuzzi,
• Christine Gravier-Pelletier,
• Gildas Bertho,
• Thierry Prangé and
• Yves Le Merrer

Beilstein J. Org. Chem. 2005, 1, No. 12, doi:10.1186/1860-5397-1-12

• afforded the corresponding azido-alcohols 11 and 12, isolated as single stereoisomers in excellent yield (95–98%). No other isomer of 11 or 12 was detected by NMR analysis, indicating that the ring-opening reaction is highly regioselective and results in the anti addition of the azido group on the opposite