Sordarin, an antifungal agent with a unique mode of action

• Huan Liang

Beilstein J. Org. Chem. 2008, 4, No. 31, doi:10.3762/bjoc.4.31

• , formation of an enol triflate using phenyl triflimide and installation of the isopropyl group by an addition-elimination sequence using a thienylcuprate reagent. Removal of the MOM groups and selective oxidation of the allylic alcohol by MnO2 led to the cycloaddition substrate 33, heating of which at 40 °C