Thematic series on supramolecular chemistry

• Christoph A. Schalley

Beilstein J. Org. Chem. 2009, 5, No. 76, doi:10.3762/bjoc.5.76

• successfully transferred to neutral and anionic hosts. Nowadays, multivalent interactions start to play a significant role for host-guest chemistry. But supramolecular chemistry is much more than molecular recognition. Concepts such as templated synthesis, (hierarchical) self-assembly, and self-sorting have

• Christoph A. Schalley Institut für Chemie und Biochemie der Freien Universität Berlin, Takustr. 3, D-14195 Berlin, Germany 10.3762/bjoc.5.76 “Some might say that supramolecular systems rescued physical organic chemistry. The discovery of crown ethers gave the field new recognition: molecular

• recognition.” [1] As the above citation from a paper by Julius Rebek and his coworkers indicates, supramolecular chemistry at its beginning gave new impetus to physical organic chemistry, which at that time had got trapped in ever more detailed kinetic studies. Early on, the nature of non-covalent

Chiral amplification in a cyanobiphenyl nematic liquid crystal doped with helicene-like derivatives

• Alberta Ferrarini,
• Silvia Pieraccini,
• Stefano Masiero and
• Gian Piero Spada

Beilstein J. Org. Chem. 2009, 5, No. 50, doi:10.3762/bjoc.5.50

• (as, for instance, the widely used commercial mixture E7 from BDH) [33][34][35][36][37][38][39][40][41][42][43][44][45] and this has been viewed as a consequence of their structural analogy and molecular recognition via core–core interactions with the host molecules [46][47]. To avoid confusion with

Structural studies on encapsulation of tetrahedral and octahedral anions by a protonated octaaminocryptand cage

• I. Ravikumar,
• P. S. Lakshminarayanan,
• E. Suresh and
• Pradyut Ghosh

Beilstein J. Org. Chem. 2009, 5, No. 41, doi:10.3762/bjoc.5.41

• . Keywords: anion receptor; cryptand; molecular recognition; proton cage; Introduction In recent years considerable efforts have been made in elucidating the coordination chemistry of anions because of their vital roles in biological systems [1], medicine [2], catalysis [3], and environmental issues [4

Quinoline based receptor in fluorometric discrimination of carboxylic acids

• Kumaresh Ghosh,
• Suman Adhikari,
• Asoke P. Chattopadhyay and
• Purnendu Roy Chowdhury

Beilstein J. Org. Chem. 2008, 4, No. 52, doi:10.3762/bjoc.4.52

• ions and molecules by designed synthetic receptors is currently of major interest in the area of molecular recognition [1][2][3]. Among various sensing techniques available for clinical, biological and environmental analyses, fluorescence sensing is unique because of high sensitivity and compatibility

• probes close enough to function as an excimer, are proved to be useful to read out the molecular recognition process more conveniently [8][9]. The recognition and sensing of carboxylic acids has attracted considerable attention owing to their important role in biology [10]. The recognition of both mono

Synthesis of deep- cavity fluorous calix[4]arenes as molecular recognition scaffolds

• Maksim Osipov,
• Qianli Chu,
• Steven J. Geib,
• Dennis P. Curran and
• Stephen G. Weber

Beilstein J. Org. Chem. 2008, 4, No. 36, doi:10.3762/bjoc.4.36

• ; organofluorine; (perfluoroalkyl)alkyl aryl ethers; Introduction Calixarenes [1] are one of the most useful types of macrocyclic scaffolds. Since first reported by Zinke and Ziegler [2], calix[4]arenes have been used for a variety of molecular recognition, nanotechnology, and supramolecular applications. These

• enhance the formation of a single conformer [12]. Of the four possible conformations, the cone is the most desirable for molecular recognition and sensing applications because it has the largest available surface area for host-guest interactions [10]. With appropriate functionality and conformation, the

• extraction of organic substrates into a fluorous liquid phase via hydrogen bonding [21]. Combining the selective nature of fluorous chemistry with the extensive molecular recognition capabilities of calixarenes should generate a scaffold for selective molecular receptors, yet few reports exist that detail

A hydrogen- bonded channel structure formed by a complex of uracil and melamine

• Reji Thomas and
• G. U. Kulkarni

Beilstein J. Org. Chem. 2007, 3, No. 17, doi:10.1186/1860-5397-3-17

• expectation that the structure may involve channels as in the reported structure of the 1:1 molecular complex of cyanuric acid and melamine. In this article, we describe the structure of the hydrogen bonded adduct of uracil and melamine, and bring out the role of uracil in molecular recognition. Rod-shaped

• different, in shape and dimension. This clearly indicates the role of the uracil molecule in directing the shape of the channel structure. In conclusion, we have illustrated the molecular recognition process of melamine with nucleobase uracil. We have also established the presence of channels, in the three

Molecular recognition. 1. Crystal structures of hexaazamacrocyclic amines containing p-xylylene spacers and their adducts with acids

• Teresa Borowiak,
• Grzegorz Dutkiewicz,
• Maciej Kubicki,
• Marek Pietraszkiewicz,
• Agnieszka Gil and
• Rainer Mattes

Beilstein J. Org. Chem. 2005, 1, No. 16, doi:10.1186/1860-5397-1-16

• adduct of; Hydrogen bonding; Molecular recognition; Two-dimensional supramolecular frameworks; Introduction Macrocyclic polyamines are well-known to participate in molecular recognition phenomena with different kinds of substrates such as organic and inorganic anions or neutral molecules[1] that give