Ru-catalyzed dehydrogenative coupling of carboxylic acids and silanes - a new method for the preparation of silyl ester

• Guo-Bin Liu and
• Hong-Yun Zhao

Beilstein J. Org. Chem. 2008, 4, No. 27, doi:10.3762/bjoc.4.27

• )3Cl [46] and promoted by organocatalyst such as triphenylphosphine [47]. Generally, catalysts such as transition metals are expensive. [CuH(Ph3P)] requires a multiple-step synthetic approach and in-situ generation protocols. Results and Discussion In this communication, we wish to report the first

Towards practical biocatalytic Baeyer- Villiger reactions: applying a thermostable enzyme in the gram- scale synthesis of optically- active lactones in a two-liquid- phase system

• Frank Schulz,
• François Leca,
• Frank Hollmann and
• Manfred T. Reetz

Beilstein J. Org. Chem. 2005, 1, No. 10, doi:10.1186/1860-5397-1-10

• . We compared the system developed in this study to an analogous synthetic organocatalyst for the enantioselective BV-oxidation as described by Murahashi et al. in 2002.[13] The Murahashi system is related to PAMO because it also uses a flavin-derived catalyst within a chiral environment. Of course

• . Comparison of P3-PAMO with Murahashi's chiral bisflavin organocatalyst as a chemical model catalyst for enantioselective BV-oxidations. Supporting Information Supporting Information File 12: Experimental section. Acknowledgements We gratefully acknowledge a gift of the plasmid pADHB1M1-kan encoding 2°ADH