One-pot synthesis of ethylmaltol from maltol

• Immanuel Plangger,
• Marcel Jenny,
• Gregor Plangger and
• Thomas Magauer

Beilstein J. Org. Chem. 2025, 21, 2755–2760, doi:10.3762/bjoc.21.212

• synthesis of ethylmaltol from a renewable precursor. Keywords: ethylmaltol; flavor enhancer; maltol; methylation; 4-pyrones; Introduction In 1969, a Pfizer patent first disclosed ethylmaltol (1) as a powerful, purely synthetic flavor and aroma enhancer (Scheme 1a) [1]. It has been found to have a 6-times