Synthesis and characterization of water-soluble C₆₀–peptide conjugates

• Yue Ma,
• Lorenzo Persi and
• Yoko Yamakoshi

Beilstein J. Org. Chem. 2024, 20, 777–786, doi:10.3762/bjoc.20.71

• example, as a photosensitizer in photodynamic therapy. Keywords: biomaterial; fullerene; peptide; water-soluble; Introduction Since the seminal discovery in 1985 by Kroto, Smalley, Curl, and co-workers [1], fullerenes, specifically buckminsterfullerene C60, have intrigued the scientific community. The

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

• Luke O. Jones,
• Leah Williams,
• Tasmin Boam,
• Martin Kalmet,
• Chidubem Oguike and
• Fiona L. Hatton

Beilstein J. Org. Chem. 2021, 17, 2553–2569, doi:10.3762/bjoc.17.171

• used are implantable biomaterials or polymeric hydrogels [18]. The issue with implantable biomaterials is that the implantation process requires the fabrication of the biomaterial component, trained physicians, post-operation patient distress, potential scarring, risk of infection, and often causes

• leaking from the implant site to other tissues, and posing difficulties in generating the desired implant geometry [73]. An alternative proposal is the use of cryogels. This process typically results in a biomaterial with a unique macroporous network, shape-memory properties, and exceptional flexibility

• ]. Additional to the work done by Bauleth-Ramos et al., a biomaterial-based vaccination system has been developed by Bencherif et al. [27]. It used minimal extracorporeal manipulation to provide in situ enhancement of dendritic cell (DC) numbers, a physical space where DCs interface with transplanted tumour

Preparation of Pickering emulsions through interfacial adsorption by soft cyclodextrin nanogels

• Shintaro Kawano,
• Toshiyuki Kida,
• Mitsuru Akashi,
• Hirofumi Sato,
• Motohiro Shizuma and
• Daisuke Ono

Beilstein J. Org. Chem. 2015, 11, 2355–2364, doi:10.3762/bjoc.11.257

• Shintaro Kawano Toshiyuki Kida Mitsuru Akashi Hirofumi Sato Motohiro Shizuma Daisuke Ono Biomaterial and Commodity Chemicals Research Division, Osaka Municipal Technical Research Institute, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Japan Department of Applied Chemistry, Graduate School of

Regulation of integrin and growth factor signaling in biomaterials for osteodifferentiation

• Qiang Wei,
• Theresa L. M. Pohl,
• Anja Seckinger,
• Joachim P. Spatz and
• Elisabetta A. Cavalcanti-Adam

Beilstein J. Org. Chem. 2015, 11, 773–783, doi:10.3762/bjoc.11.87

• unexpected directions. Therefore, the appropriate extracellular environment must be carefully considered in biomaterial science to employ stem cells for cell therapies. Integrin ligands and growth factors are two of the most important parameters in the stem cell niche to determine the cell fate. In this

Detonation nanodiamonds biofunctionalization and immobilization to titanium alloy surfaces as first steps towards medical application

• Juliana P. L. Gonçalves,
• Afnan Q. Shaikh,
• Manuela Reitzig,
• Daria A. Kovalenko,
• Jan Michael,
• René Beutner,
• Gianaurelio Cuniberti,
• Dieter Scharnweber and
• Jörg Opitz

Beilstein J. Org. Chem. 2014, 10, 2765–2773, doi:10.3762/bjoc.10.293

• on chemical modification of the nanodiamond surface with phosphate groups and their electrochemically assisted immobilization on titanium-based materials to increase adhesion at biomaterial surfaces. The starting material is detonation nanodiamond, which exhibits a heterogeneous surface due to the

Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment

• Christiane E. Kupper,
• Ruben R. Rosencrantz,
• Birgit Henßen,
• Helena Pelantová,
• Stephan Thönes,
• Anna Drozdová,
• Vladimir Křen and
• Lothar Elling

Beilstein J. Org. Chem. 2012, 8, 712–725, doi:10.3762/bjoc.8.80

• synthesised products could be valuable tools to follow glycan immobilisation on biomaterial surfaces. Preliminary results already demonstrate that biotinylated poly-LacNAc oligosaccharides (with deprotected NH2-linker) are detectable by streptavidin-peroxidase-detection after immobilisation on amine-reactive