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Search for "diarylacetic acid" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

Efficient one-step synthesis of diarylacetic acids by electrochemical direct carboxylation of diarylmethanol compounds in DMSO

  • Hisanori Senboku and
  • Mizuki Hayama

Beilstein J. Org. Chem. 2024, 20, 2392–2400, doi:10.3762/bjoc.20.203

Graphical Abstract
  • diarylacetic acids from diarylmethanol species and carbon dioxide without transformation of the hydroxy group into appropriate leaving groups, such as halides and esters including carbonates. Keywords: C(sp3)–O bond cleavage; diarylacetic acid; diarylmethanol; electrochemical reduction; fixation of carbon
  • electrochemical and the second efficient example of diarylacetic acid 2 synthesis from diarylmethanol compounds 1 and carbon dioxide in one step. Results and Discussion Although we have previously obtained diphenylacetic acid (2a) in 81% yield by electrochemical carboxylation of diphenylmethanol (1a) [19
  • and then extracted with ethyl acetate (30 mL × 5). The combined ethyl acetate solution was washed with H2O (100 mL × 3) and dried over MgSO4. Evaporation of the solvent gave a diarylacetic acid 2. The organic layer, extracted by aqueous saturated NaHCO3, was washed with H2O (100 mL × 3) and dried over
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Published 20 Sep 2024
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